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Heterocyclic compounds -
Pyrrole
Lecture by
S.Mathivanan., M.Pharm
Assistant professor
Pharmacy
Introduction
Pyrrole is an important five membered
heterocyclic compound possessing a
nitrogen atom as hetero atom.
plays important role in the chemistry of
living organisms.
The essential structural feature of
chlorophyll and heme is porphyrin,
which consists of four Pyrrole rings
held together by bridges.
Heterocyclic compounds
Heterocyclic compounds
Properties of Pyrrole
Heterocyclic compounds
Resonance of Pyrrole
Heterocyclic compounds
Heterocyclic compounds
Acidic character
Heterocyclic compounds
 The acidic strength of pyrrole is very
weak, which is similar to acetylene.
Synthesis of Pyrrole
Heterocyclic compounds
Heterocyclic compounds
Mechanism
Heterocyclic compounds
Heterocyclic compounds
Mechanism
Heterocyclic compounds
Heterocyclic compounds
Heterocyclic compounds
5.Mixture of acetylene and ammonia
are passed through red-hot tube to
yield Pyrrole.
6.From distillation of Succinamide
Heterocyclic compounds
2C2H2 + NH3 C4H5N +
H2
Reactions of Pyrrole
Heterocyclic compounds
Heterocyclic compounds
Heterocyclic compounds
Heterocyclic compounds
Heterocyclic compounds
Grignard Reaction
Heterocyclic compounds
Heterocyclic compounds
 Obatoclax : It is used to treat
Leukaemia, Lymphoma, Myelofibrosis
and mastocytosis
Heterocyclic compounds
Browse to know more
Thank you dear students...!!!!
Heterocyclic compounds

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