This chapter review focuses on infections of the skin and eyes, including characteristics, symptoms, and treatment of impetigo, rubella, acne, erysipelas, cutaneous anthrax, varicella-zoster, measles, smallpox, and shingles. It also discusses necrotizing fasciitis, sweat glands and bacteria, folliculitis, blackheads, staphylococcal abscesses, anthropods, trachoma, the differences between cutaneous and inhalation anthrax, candidiasis, and HSV-1.