Most children with cystic fibrosis have frequent lung infections and digestive difficulties. Some people have mild cases, with onset of minor respiratory problems in adulthood. Some men with cystic fibrosis only exhibit the symptom of infertility. Which exception to Mendelian laws of inheritance best explains these symptoms? 1.) incomplete dominance 2.) pleiotropy 3.) epistasis 4.) codominance 5.) overdominance Solution 2. Pleiotropy. Some genes influence not only the triats generally associated with them but also many other triats. The multiple effect of a gene is called pleiotropy and gene having multiple phenotypic effects is called pleiotropic gene. Pleiotropic genes may not have equal influecne on all triats they control and these genes may cause a very evident expression of its specific triat (major effect) and less evident effects of its other triat (secondsry effect).