This document discusses how advances in genome sequencing and gene editing technologies will impact humans by 2020. Key points include: genomes can now be sequenced for $100, with the goal of sequencing 100,000 genomes by 2020; this data will provide opportunities to understand and construct the human genome; gene editing allows modifying genomes by targeting specific genes, though challenges remain around immune response and safety; gene editing could enhance human traits like strength and endurance through targeting genes like IGF-1 and myostatin.