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CANCER
Global Vision
Dr Madhuri
What Is Cancer?
What is ‘ Cancer’
Healthy Cells
• Cells represent the smallest,
functional unit of our existence
which contains cytoplasm and a
nucleus (i.e. metabolism,
reproduction, day to day
functions)
• Cells have a specialized function
depending on their location in
the body.
• Cells grow, replicate and repair
body organs.
• The genetic material (DNA/RNA)
and your immune system
regulate this process.
Different Types of Cells
• Blood cells
• Muscle cells (smooth,
striated, cardiac)
• Nerve cells
• Bone cells
• Cartilage cells
• Liver (hepa) cells
Define Cancer
• Cancer is a term used to describe a large
group of diseases that are characterized by a
cellular malfunction. Healthy cells are
programmed to “know what to do and when
to do it”. Cancerous cells do not have this
programming and therefore grow and
replicate out of control. They also serve no
physiological function. These cells are now
termed a neoplasm.
This neoplasmic mass often forms a
clumping of cells known as a tumor.
Loss of Normal Growth Control
Cancer
cell division
Fourth or
later mutation
Third
mutation
Second
mutation
First
mutation
Uncontrolled growth
Cell Suicide or Apoptosis
Cell damage—
no repair
Normal
cell division
Example of Normal Growth
Cell migration
Dermis
Dividing cells in
basal layer
Dead cells
shed from
outer surface
Epidermis
The Beginning of Cancerous Growth
Underlying tissue
Invasion and Metastasis
3
Cancer cells reinvade
and grow at new
location
1
Cancer cells invade
surrounding tissues and
blood vessels
2
Cancer cells are
transported by the
circulatory system to
distant sites
Malignant versus Benign Tumors
Malignant (cancer) cells
invade neighboring
tissues, enter blood
vessels, and metastasize
to different sites
Time
Benign (not cancer) tumor
cells grow
only locally and cannot
spread by invasion or
metastasis
Bladder Cancer
Bladder Cancer
Lung Cancer
Bladder Cancer
Lung Cancer
Breast Cancer
Bladder Cancer
Lung Cancer
Breast Cancer
Melanoma
Bladder Cancer
Lung Cancer
Breast Cancer
Melanoma
Colon and Rectal Cancer
Bladder Cancer
Lung Cancer
Breast Cancer
Melanoma
Colon and Rectal Cancer
Non-Hodgkin Lymphoma
Bladder Cancer
Lung Cancer
Breast Cancer
Melanoma
Colon and Rectal Cancer
Non-Hodgkin Lymphoma
Endometrial Cancer
Bladder Cancer
Lung Cancer
Breast Cancer
Melanoma
Colon and Rectal Cancer
Non-Hodgkin Lymphoma
Endometrial Cancer
Pancreatic Cancer
Bladder Cancer
Lung Cancer
Breast Cancer
Melanoma
Colon and Rectal Cancer
Non-Hodgkin Lymphoma
Endometrial Cancer
Pancreatic Cancer
Kidney (Renal Cell) Cancer
Bladder Cancer
Lung Cancer
Breast Cancer
Melanoma
Colon and Rectal Cancer
Non-Hodgkin Lymphoma
Endometrial Cancer
Pancreatic Cancer
Kidney (Renal Cell) Cancer
Prostate Cancer
Bladder Cancer
Lung Cancer
Breast Cancer
Melanoma
Colon and Rectal Cancer
Non-Hodgkin Lymphoma
Endometrial Cancer
Pancreatic Cancer
Kidney (Renal Cell) Cancer
Prostate Cancer
Thyroid Cancer
Leukemia
I helpyou to havecancer
Causes
Inherited
Risk Factors
Environmental Factors
Common environmental factors leading to cancer death include:
tobacco (25-30%)
Common environmental factors leading to cancer death include:
tobacco (25-30%)
diet and obesity (30-35%)
Common environmental factors leading to cancer death include:
tobacco (25-30%)
infections (15-20%)
diet and obesity (30-35%)
Common environmental factors leading to cancer death include:
tobacco (25-30%)
infections (15-20%)
diet and obesity (30-35%)
Radiation
Stress
lack of physical activity
environmental pollutants
62 TOXIC CHEMICALS ARE IN THE AVERAGE HOME!
‘RED ALERT’ Signs
&
Symptoms
Cancer Detection and Diagnosis
Early Cancer May Not Have Any Symptoms
DIAGNOSIS
• Self examinations
• Clinical examinations
• Screening
• Biopsy
• X-rays, CT scans, MRI scans, PET scans, and
ultrasound scans
• Molecular diagnostic test
Cervical Cancer Screening
Abnormal
Pap smear
Normal
Pap smear
Breast Cancer Screening
Prostate and Ovarian Cancer Screening
Thought of the Day
If you don’t ‘FIND’ time…
For Today’s Fitness…..!!
THEN….
Probably You are ‘SAVING’ that time…
For Tomorrow’s Sickness………!!
Dietary and Lifestyle Changes
to Help Prevent Cancer
What Causes Cancer?
Non-modifiable
Genetics Environmental
Modifiable
Lifestyle Diet
Our Focus!
Modifiable Risk Factors
– Lifestyle
– Diet
Up to 1/3 of cancers can be avoided with a
nutritious diet, maintenance of a healthy
weight, and an active lifestyle
Optimize your diet!
1. Plant-based foods
2. Limit red and processed meats
3. Avoid grilling and frying foods
4. Limit alcohol
5. Avoid Tobacco
6. Limit exposure to carcinogen
Plant-based Diets
 High in fruits, vegetables, nuts, beans, etc.
 Dietary fiber
 Vitamins, minerals, phytonutrients, and antioxidants
 Low in total and saturated fat
Benefits of Dietary Fiber
 Speeds up digestion
 Eliminates cancer compounds from the body
 Changes the bacteria in the gut to good bacteria
 Getting enough fiber can reduce the risk of:
Colorectal cancer
Breast cancer
Some head/neck cancers
 Whole Grains
 Legumes
 Vegetables
 Fruits
 Recommendations:
 Men: 32g per day
 Women: 25g per day
 (14g of dietary fiber per 1,000
calories daily)
Sources of Fiber
Benefits of Vitamins and Phytonutrients
• Act as antioxidants in the body
 Antioxidants:
 Reduce cells that damage the body
 Control cell growth and death
 These compounds may be protective against:
 Breast cancer
 Prostate cancer
 Colon cancer
 Bladder cancer
 Lung cancer
 Esophageal cancer
Sources of Vitamins and Phytonutrients
• Vitamin A: liver, eggs, dairy
• ß-carotene: carrot, sweet-
potato, pumpkin, dark leafy
green vegetables
• Vitamin E: vegetable oils, nuts,
leafy green vegetables, sweet
potatoes, carrots, and tomatoes
• Vitamin C: citrus fruits, broccoli,
cabbage
• Recommendations:
– 2 cups of fruit daily
– 2.5 to 3 cups of vegetables daily
Benefits of Consuming a Low Diet
 Low intakes of saturated fat may prevent inflammation
 Inflammation is often associated with cancer development
 Increased waist
circumference and body
weight (obesity) may
increase the risk of
developing:
Colon cancer
Breast cancer
Multiple myeloma
Optimize your diet!
1. Plant-based foods
2. Limit red and processed meats
3. Avoid grilling and frying foods
4. Limit alcohol
Limit Red and Processed Meats
 Some processed
meats may contain
carcinogens
 Recommendations:
 Eat less than 18
ounces of red meat
a week to reduce
cancer risk
 Red meats:
Hamburgers, steak,
lamb roast, pork
chops
 Processed meats:
Smoked/cured/salted
meat, meat with
added preservatives
such as hotdogs,
bacon, salami,
sausage
Optimize your diet!
1. Plant-based foods
2. Limit red and processed meats
3. Avoid grilling and frying foods
4. Limit alcohol
Avoid Grilling and Frying Foods!
• Cancer causing compounds are
produced when animal products are
grilled or fried
• Chemicals formed when fat drips off
the meat into flames
• Try to replace grilling and frying with
baking, steaming, or boiling!
Optimize your diet!
1. Plant-based foods
2. Limit red and processed meats
3. Avoid grilling and frying foods
4. Limit alcohol
Limit Alcohol Consumption
• May damage DNA, increasing the risk of cancer
• High alcohol consumption is associated with:
– Head and neck cancer
– Mouth cancer
– Pharynx/Larynx cancer
• Recommendations:
• Men: 2 drinks per day
• Women 1 drink per day
 Esophagus cancer
 Breast cancer
 Liver cancer
Optimize your diet!
1. Plant-based foods
2. Limit red and processed meats
3. Avoid grilling and frying foods
4. Limit alcohol
5. Avoid Tobacco
6. Limit exposure to carcinogen
Optimize your diet!
1. Plant-based foods
2. Limit red and processed meats
3. Avoid grilling and frying foods
4. Limit alcohol
5. Avoid Tobacco
6. Limit exposure to carcinogen
Industrial Pollution
1930
Incidence of
Most Cancers
Year
199019701950
Protect Yourself From Excessive Sunlight
• Avoid CT Scans as they have been linked to progression of
cancer
• Avoid EMF’s (electromagnetic field)
– Electronics
– Power Lines
– Modems
– appliances
MINERAL OIL (LIQUID PETROLEUM)
IS A BY PRODUCT OF PETROLEUM AND IS KNOWN TO INCREASE THE RISK OF CANCER.
*THESE CHEMICALS SLOWLY POISON US THROUGH REPEATED USE!!!
Avoid COSMETICS
containing
• Formaldehyde
• Parabens
• phthalates (endocrin
disrupting preservatives)
*100 unique chemicals in every
day personal products .
Microwave Popcorn- Diaacetyl
Non-Organic Food- Pesticides
Canned Food- Bisphenol-A or BPA
Processed Meat- Numerous Chemicals
and preservatives
Potato Chips- Articial Flavors &
preservatives
Hydrogenated Oil
Sugars- High fructose corn syrup
Diet Food
Highly salted or fried or pickled food
Summary
•There are many causes of cancer
•Some causes can be changed
•Diet is a modifiable risk factor
•With these small steps, you can help reduce your risk
of cancer-causing agents!
THINK AGAIN
THANK YOU

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"Global Vision NGO" - Cancer awareness

  • 3. What is ‘ Cancer’
  • 4. Healthy Cells • Cells represent the smallest, functional unit of our existence which contains cytoplasm and a nucleus (i.e. metabolism, reproduction, day to day functions) • Cells have a specialized function depending on their location in the body. • Cells grow, replicate and repair body organs. • The genetic material (DNA/RNA) and your immune system regulate this process.
  • 5. Different Types of Cells • Blood cells • Muscle cells (smooth, striated, cardiac) • Nerve cells • Bone cells • Cartilage cells • Liver (hepa) cells
  • 6. Define Cancer • Cancer is a term used to describe a large group of diseases that are characterized by a cellular malfunction. Healthy cells are programmed to “know what to do and when to do it”. Cancerous cells do not have this programming and therefore grow and replicate out of control. They also serve no physiological function. These cells are now termed a neoplasm.
  • 7. This neoplasmic mass often forms a clumping of cells known as a tumor.
  • 8. Loss of Normal Growth Control Cancer cell division Fourth or later mutation Third mutation Second mutation First mutation Uncontrolled growth Cell Suicide or Apoptosis Cell damage— no repair Normal cell division
  • 9. Example of Normal Growth Cell migration Dermis Dividing cells in basal layer Dead cells shed from outer surface Epidermis
  • 10. The Beginning of Cancerous Growth Underlying tissue
  • 11. Invasion and Metastasis 3 Cancer cells reinvade and grow at new location 1 Cancer cells invade surrounding tissues and blood vessels 2 Cancer cells are transported by the circulatory system to distant sites
  • 12. Malignant versus Benign Tumors Malignant (cancer) cells invade neighboring tissues, enter blood vessels, and metastasize to different sites Time Benign (not cancer) tumor cells grow only locally and cannot spread by invasion or metastasis
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  • 18. Bladder Cancer Lung Cancer Breast Cancer Melanoma Colon and Rectal Cancer
  • 19. Bladder Cancer Lung Cancer Breast Cancer Melanoma Colon and Rectal Cancer Non-Hodgkin Lymphoma
  • 20. Bladder Cancer Lung Cancer Breast Cancer Melanoma Colon and Rectal Cancer Non-Hodgkin Lymphoma Endometrial Cancer
  • 21. Bladder Cancer Lung Cancer Breast Cancer Melanoma Colon and Rectal Cancer Non-Hodgkin Lymphoma Endometrial Cancer Pancreatic Cancer
  • 22. Bladder Cancer Lung Cancer Breast Cancer Melanoma Colon and Rectal Cancer Non-Hodgkin Lymphoma Endometrial Cancer Pancreatic Cancer Kidney (Renal Cell) Cancer
  • 23. Bladder Cancer Lung Cancer Breast Cancer Melanoma Colon and Rectal Cancer Non-Hodgkin Lymphoma Endometrial Cancer Pancreatic Cancer Kidney (Renal Cell) Cancer Prostate Cancer
  • 24. Bladder Cancer Lung Cancer Breast Cancer Melanoma Colon and Rectal Cancer Non-Hodgkin Lymphoma Endometrial Cancer Pancreatic Cancer Kidney (Renal Cell) Cancer Prostate Cancer Thyroid Cancer
  • 26. I helpyou to havecancer
  • 28. Common environmental factors leading to cancer death include: tobacco (25-30%)
  • 29. Common environmental factors leading to cancer death include: tobacco (25-30%) diet and obesity (30-35%)
  • 30. Common environmental factors leading to cancer death include: tobacco (25-30%) infections (15-20%) diet and obesity (30-35%)
  • 31. Common environmental factors leading to cancer death include: tobacco (25-30%) infections (15-20%) diet and obesity (30-35%) Radiation Stress lack of physical activity environmental pollutants
  • 32. 62 TOXIC CHEMICALS ARE IN THE AVERAGE HOME!
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  • 43. Cancer Detection and Diagnosis
  • 44. Early Cancer May Not Have Any Symptoms
  • 45. DIAGNOSIS • Self examinations • Clinical examinations • Screening • Biopsy • X-rays, CT scans, MRI scans, PET scans, and ultrasound scans • Molecular diagnostic test
  • 46. Cervical Cancer Screening Abnormal Pap smear Normal Pap smear
  • 48. Prostate and Ovarian Cancer Screening
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  • 50. Thought of the Day If you don’t ‘FIND’ time… For Today’s Fitness…..!! THEN…. Probably You are ‘SAVING’ that time… For Tomorrow’s Sickness………!!
  • 51. Dietary and Lifestyle Changes to Help Prevent Cancer
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  • 53. What Causes Cancer? Non-modifiable Genetics Environmental Modifiable Lifestyle Diet Our Focus!
  • 54. Modifiable Risk Factors – Lifestyle – Diet Up to 1/3 of cancers can be avoided with a nutritious diet, maintenance of a healthy weight, and an active lifestyle
  • 55. Optimize your diet! 1. Plant-based foods 2. Limit red and processed meats 3. Avoid grilling and frying foods 4. Limit alcohol 5. Avoid Tobacco 6. Limit exposure to carcinogen
  • 56. Plant-based Diets  High in fruits, vegetables, nuts, beans, etc.  Dietary fiber  Vitamins, minerals, phytonutrients, and antioxidants  Low in total and saturated fat
  • 57. Benefits of Dietary Fiber  Speeds up digestion  Eliminates cancer compounds from the body  Changes the bacteria in the gut to good bacteria  Getting enough fiber can reduce the risk of: Colorectal cancer Breast cancer Some head/neck cancers
  • 58.  Whole Grains  Legumes  Vegetables  Fruits  Recommendations:  Men: 32g per day  Women: 25g per day  (14g of dietary fiber per 1,000 calories daily) Sources of Fiber
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  • 60. Benefits of Vitamins and Phytonutrients • Act as antioxidants in the body  Antioxidants:  Reduce cells that damage the body  Control cell growth and death  These compounds may be protective against:  Breast cancer  Prostate cancer  Colon cancer  Bladder cancer  Lung cancer  Esophageal cancer
  • 61. Sources of Vitamins and Phytonutrients • Vitamin A: liver, eggs, dairy • ß-carotene: carrot, sweet- potato, pumpkin, dark leafy green vegetables • Vitamin E: vegetable oils, nuts, leafy green vegetables, sweet potatoes, carrots, and tomatoes • Vitamin C: citrus fruits, broccoli, cabbage • Recommendations: – 2 cups of fruit daily – 2.5 to 3 cups of vegetables daily
  • 62. Benefits of Consuming a Low Diet  Low intakes of saturated fat may prevent inflammation  Inflammation is often associated with cancer development  Increased waist circumference and body weight (obesity) may increase the risk of developing: Colon cancer Breast cancer Multiple myeloma
  • 63. Optimize your diet! 1. Plant-based foods 2. Limit red and processed meats 3. Avoid grilling and frying foods 4. Limit alcohol
  • 64. Limit Red and Processed Meats  Some processed meats may contain carcinogens  Recommendations:  Eat less than 18 ounces of red meat a week to reduce cancer risk  Red meats: Hamburgers, steak, lamb roast, pork chops  Processed meats: Smoked/cured/salted meat, meat with added preservatives such as hotdogs, bacon, salami, sausage
  • 65. Optimize your diet! 1. Plant-based foods 2. Limit red and processed meats 3. Avoid grilling and frying foods 4. Limit alcohol
  • 66. Avoid Grilling and Frying Foods! • Cancer causing compounds are produced when animal products are grilled or fried • Chemicals formed when fat drips off the meat into flames • Try to replace grilling and frying with baking, steaming, or boiling!
  • 67. Optimize your diet! 1. Plant-based foods 2. Limit red and processed meats 3. Avoid grilling and frying foods 4. Limit alcohol
  • 68. Limit Alcohol Consumption • May damage DNA, increasing the risk of cancer • High alcohol consumption is associated with: – Head and neck cancer – Mouth cancer – Pharynx/Larynx cancer • Recommendations: • Men: 2 drinks per day • Women 1 drink per day  Esophagus cancer  Breast cancer  Liver cancer
  • 69. Optimize your diet! 1. Plant-based foods 2. Limit red and processed meats 3. Avoid grilling and frying foods 4. Limit alcohol 5. Avoid Tobacco 6. Limit exposure to carcinogen
  • 70. Optimize your diet! 1. Plant-based foods 2. Limit red and processed meats 3. Avoid grilling and frying foods 4. Limit alcohol 5. Avoid Tobacco 6. Limit exposure to carcinogen
  • 71. Industrial Pollution 1930 Incidence of Most Cancers Year 199019701950
  • 72. Protect Yourself From Excessive Sunlight
  • 73. • Avoid CT Scans as they have been linked to progression of cancer • Avoid EMF’s (electromagnetic field) – Electronics – Power Lines – Modems – appliances
  • 74. MINERAL OIL (LIQUID PETROLEUM) IS A BY PRODUCT OF PETROLEUM AND IS KNOWN TO INCREASE THE RISK OF CANCER. *THESE CHEMICALS SLOWLY POISON US THROUGH REPEATED USE!!! Avoid COSMETICS containing • Formaldehyde • Parabens • phthalates (endocrin disrupting preservatives) *100 unique chemicals in every day personal products .
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  • 80. Processed Meat- Numerous Chemicals and preservatives
  • 81. Potato Chips- Articial Flavors & preservatives
  • 83. Sugars- High fructose corn syrup
  • 85. Highly salted or fried or pickled food
  • 86. Summary •There are many causes of cancer •Some causes can be changed •Diet is a modifiable risk factor •With these small steps, you can help reduce your risk of cancer-causing agents!
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Editor's Notes

  1. NCI Web site: http://cancer.gov/cancertopics/understandingcancer
  2. NCI Web site: http://cancer.gov/cancertopics/understandingcancer
  3. NCI Web site: http://cancer.gov/cancertopics/understandingcancer
  4. NCI Web site: http://cancer.gov/cancertopics/understandingcancer
  5. NCI Web site: http://cancer.gov/cancertopics/understandingcancer
  6. NCI Web site: http://cancer.gov/cancertopics/understandingcancer
  7. NCI Web site: http://cancer.gov/cancertopics/understandingcancer
  8. NCI Web site: http://cancer.gov/cancertopics/understandingcancer
  9. NCI Web site: http://cancer.gov/cancertopics/understandingcancer
  10. NCI Web site: http://cancer.gov/cancertopics/understandingcancer
  11. NCI Web site: http://cancer.gov/cancertopics/understandingcancer
  12. NCI Web site: http://cancer.gov/cancertopics/understandingcancer
  13. NCI Web site: http://cancer.gov/cancertopics/understandingcancer