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CANCER

Zerin Ziaudeen
MBA (HM)
WHAT IS CANCER ?
TYPES OF TUMORS
TYPES OF CANCER
•
•
•
•
•
•
•
•
•

lung cancer
Breast cancer
Colon and rectal cancer
Endometrial cancer
Pancreatic cancer
...
KINDS OF CANCERS
NAMING OF CANCER
ETIOLOGY
CAUSES OF CANCER
Environmental factors

Genetic

•
•
•
•
•
•
•
•

Eg
• Retinoblastoma in Children
•
Leukemia in Mongols

T...
Factors Believed to Contribute to Global
Causes of Cancer
SIGNS AND SYMPTOMS
•
•
•
•
•

Early cancer no symptoms
Change in bowel habits or bladder functions
Sores that do not heal
...
DIAGNOSIS
•
•
•
•

Screening
Self examinations
Biopsy
X-rays, CT scans, MRI scans, PET scans, and
ultrasound scans
• Molec...
TREATMENTS
•
•
•
•
•
•
•

Surgery
Radiotherapy
Chemotherapy
Immunotherapy
Hormone therapy
Gene therapy
Cancer-specific imm...
EPIDEMOLOGY OF CANCER
2013 ESTIMATES
CANCER CAUSES IN DEVELOPED AND DEVELOPING
ECONOMIES
Cancer scenario in India

Year wise total cancer prevalence in India [ICMR, 2006; ICMR, 2009]
Statewise depiction of the most incident cancers in India [Koul, 2010; ICMR, 2001; Somdatta, 2008; Das, 2005; Sharma, 2009...
Cancer causes in India
o
o
o
o
o

Dietary habits
Tobacco
Alcohol
Radiation
Miscellaneous pollutants
ETIOLOGICAL FACTORS FOR DIFFERENT CANCERS IN INDIA
SMOKING & HOOKAH
BIDI & HOOKAH SMOKING

SMOKED MEAT,TOBACCO,
HOOKAH
BET...
COMPARISON OF CANCER
INDIA WITH GLOBAL SCENARIO
• 2020- 10 million deaths,70% in developing
countries ( Murray et al,1996)...
INDIAN SCENARIO WITH USA (2001)

Comparison of cancer; Indian scenario with USA [Fenley et al, 2001]
Preventive measures of cancer
o physical activities

o avoiding obesities
o healthy dietary practices
o reducing occupatio...
RECENT STUDIES
• Lifestyle changes reduce the risk of prostate
cancer( published in the journal Nutrition and Cancer,
was ...
Life style changes reduce the risk of prostate cancer
(Nutrition and Cancer" Lenore Arab, PhD, et al. Nutrition and Cancer...
Research aiming to suppress therapy resistance in
brain cancer (Helmholtz Association of German Research Centres. Medical ...
Fish oil reduces the risk of breast cancer (Nordqvist, Joseph.
"Fish Oils Reduce Risk Of Breast Cancer." Medical News Toda...
CONCLUSION
•
•
•
•

Increase in the no: of cancer patients every year
Factors responsible should be controlled
Create awar...
REFERENCE
• All about cancer
http://www.medicalnewstoday.com/info/cancer-oncology/

• Imran Ali,Waseem A. Wani and Kishwar...
THANK YOU
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Final cancer presentation

  1. 1. CANCER Zerin Ziaudeen MBA (HM)
  2. 2. WHAT IS CANCER ?
  3. 3. TYPES OF TUMORS
  4. 4. TYPES OF CANCER • • • • • • • • • lung cancer Breast cancer Colon and rectal cancer Endometrial cancer Pancreatic cancer Kidney cancer Prostrate cancer Thyroid cancer leukemia
  5. 5. KINDS OF CANCERS
  6. 6. NAMING OF CANCER
  7. 7. ETIOLOGY
  8. 8. CAUSES OF CANCER Environmental factors Genetic • • • • • • • • Eg • Retinoblastoma in Children • Leukemia in Mongols Tobacco Alcohol Dietary Factors Occupational exposures Viruses Parasites Customs ,habits, Lifestyles Others – sunlight, pollution, drugs
  9. 9. Factors Believed to Contribute to Global Causes of Cancer
  10. 10. SIGNS AND SYMPTOMS • • • • • Early cancer no symptoms Change in bowel habits or bladder functions Sores that do not heal Unusual bleeding or discharge Lumps or thickening of breast or other parts of the body • Indigestion or difficulty swallowing • Recent change in wart or mole • Persistent coughing or hoarseness
  11. 11. DIAGNOSIS • • • • Screening Self examinations Biopsy X-rays, CT scans, MRI scans, PET scans, and ultrasound scans • Molecular diagnostic test
  12. 12. TREATMENTS • • • • • • • Surgery Radiotherapy Chemotherapy Immunotherapy Hormone therapy Gene therapy Cancer-specific immune system cells to treat cancer
  13. 13. EPIDEMOLOGY OF CANCER
  14. 14. 2013 ESTIMATES
  15. 15. CANCER CAUSES IN DEVELOPED AND DEVELOPING ECONOMIES
  16. 16. Cancer scenario in India Year wise total cancer prevalence in India [ICMR, 2006; ICMR, 2009]
  17. 17. Statewise depiction of the most incident cancers in India [Koul, 2010; ICMR, 2001; Somdatta, 2008; Das, 2005; Sharma, 2009; Gaur, 2006; Prasad, 2005; Malothu, 2010; Sumath STATEWISE DEPICTION OF CANCER IN INDIA Statewise depiction of the most incident cancers in India [Koul, 2010; ICMR, 2001; Somdatta, 2008; Das, 2005; Sharma, 2009; Gaur, 2006; Prasad, 2005; Malothu, 2010; Sumathi, 2009; (b) http//]
  18. 18. Cancer causes in India o o o o o Dietary habits Tobacco Alcohol Radiation Miscellaneous pollutants
  19. 19. ETIOLOGICAL FACTORS FOR DIFFERENT CANCERS IN INDIA SMOKING & HOOKAH BIDI & HOOKAH SMOKING SMOKED MEAT,TOBACCO, HOOKAH BETEL NUT, PANMASALA, ALCOHOL BETEL CHEWING TOBACCO USE IN DIFFERENT FORM PAN MASALA AND ALCOHOL NUCLEAR POLLUTION TUIBUR AIR POLLUTION GALL STONES PAN MASALA & GUTKA Etiological factors for the prevalence of different cancers in India [Koul et al, 2010; ICMR, 2001; Somdatta et al, 2008; Sharma et al, 2009; Gaur et al, 2006; Prasad et al, 2005; Malothu et al, 2010; Sumathi et al, 2009; (b): http//
  20. 20. COMPARISON OF CANCER INDIA WITH GLOBAL SCENARIO • 2020- 10 million deaths,70% in developing countries ( Murray et al,1996) • Incidence in India less than developed countries (Fenley et al ,2001) • Lung cancer worldwide 14%,all of india 6.8%(Nandakumar,2001) • South east asian countries including India, lower rates of stomach cancer (Parkin et al,1999,WHO,2001),mizoram shows increased no cases ( Hadjiiski et al, 2006)
  21. 21. INDIAN SCENARIO WITH USA (2001) Comparison of cancer; Indian scenario with USA [Fenley et al, 2001]
  22. 22. Preventive measures of cancer o physical activities o avoiding obesities o healthy dietary practices o reducing occupational and environmental exposures o reducing alcohol uses o immunization against hepatitis B virus o safe sexual practices for avoiding cancer genesis
  23. 23. RECENT STUDIES • Lifestyle changes reduce the risk of prostate cancer( published in the journal Nutrition and Cancer, was carried out by researchers at UCLA's Jonsson Comprehensive Cancer Center (JCCC).) • Researchers Aiming To Suppress Therapy Resistance In Brain Cancer (http://www.medicalnewstoday.com/releases/262571.php) • Fish Oils Reduce Risk Of Breast Cancer (http://www.medicalnewstoday.com/articles/262612.php)
  24. 24. Life style changes reduce the risk of prostate cancer (Nutrition and Cancer" Lenore Arab, PhD, et al. Nutrition and Cancer Jun-2013) • Focuses on 8 new lifestyle recommendation by WCRF • Encouraged physical activity and consumption of food low in caloric density(under 125kcal/100 grams of food) • who followed less than 4 recommendation at higher risk(38%)
  25. 25. Research aiming to suppress therapy resistance in brain cancer (Helmholtz Association of German Research Centres. Medical News Today. MediLexicon, Intl., 29 Jun. 2013. Web) • Gliomas are malignant brain tumors, treatment combines radiotherapy with anticancer drug temozolomide • Some cases shows resistance , DNA repair mechanism aided by NAD+ molecule • QRTP enzyme break down quinolinic acid to NAD+ molecule • Agent directed against enzyme help suppress therapy resistance in brain
  26. 26. Fish oil reduces the risk of breast cancer (Nordqvist, Joseph. "Fish Oils Reduce Risk Of Breast Cancer." Medical News Today. MediLexicon, Intl., 28 Jun. 2013. Web.) • Links fish,n-3PUFA intake and risk of breast cancer • Marine n-3PUFA intake associated with 14% reduced risk of breast cancer • For every 0.1g/day increase in consumption ,risk reduced by 5%
  27. 27. CONCLUSION • • • • Increase in the no: of cancer patients every year Factors responsible should be controlled Create awareness about cancer and its prevention Careful about diet and lifestyle
  28. 28. REFERENCE • All about cancer http://www.medicalnewstoday.com/info/cancer-oncology/ • Imran Ali,Waseem A. Wani and Kishwar Saleem,( 2011)Cancer Scenario in India with Future Perspectives, Cancer Therapy Vol 8, 56-70 • National cancer institute, http://www.cancer.gov/ • Gobal cancer facts and figures, http://www.cancer.org/acs/groups/content/@epidemiology surveilance/documents/document/acspc-027766.pdf
  29. 29. THANK YOU
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