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Journal Reading
Presenter: FM R2盧敬文
Supervisor: VS 賴德聰
2020.01.31
• important factors associated with
stroke treatment and recovery
include race/ethnicity,
socioeconomic status,
and premorbid functional status.
• Females tend to be older
when they have their stroke
• more likely to have hypertension
and atrial fibrillation than men.
• During acute care,
• females are less likely to receive standard of care for stroke
management
including antiplatelets, statins, and tissue plasminogen activator (tPA) after an
ischemic stroke.
• Females tend to experience less functional gain during rehabilitation
• less likely to be discharged home
• less likely to report an identified caregiver.
• uses total Scores vs. individual rehabilitation Goals ?
 females are more likely to reach their clinician-identified
rehabilitation goals
• Purpose:
examine sex differences in
achieving a universally desired rehabilitation outcome—
functional independence at discharge
and the impact that social living situation
has in explaining those differences.
METHODS:
Data Source
Medicare data
from the Centers for Medicare and Medicaid Services
study was approved by the university’s
institutional review board
Study Population
• ICD-9 codes:
hemorrhagic stroke (430–432),
ischemic stroke (433–434),
acute cerebrovascular diseases
ischemic (436),
late effects of acute cerebrovascular diseases
(438)
Independent Variables
• sex (male vs. female)
• premorbid living arrangement
(lived alone, lived with family or spouse, lived
with a hired caregiver).
Dependent Variables
• FIM score at discharge from the IRF.
The FIM consists of 18 items in self-care,
motor, speech, and cognition categories
• Functional independence measure
score at discharge for each individual
FIM item was dichotomized as ≥5 or <5.
Clinical Covariates
• Rehabilitation length of stay (LOS) : 4 categories
(<10 days, 11–22 days, 23–35 days, >35 days)
• Elixhauser Comorbidity Index
• uses an extensive list of comorbidities that may interfere with an individual’s
progress during rehabilitation
(no comorbidities, 1–2 comorbidities, >3 comorbidities)
• type of stroke (hemorrhagic,ischemic, other)
• tPA treatment during their acute care admission for their stroke (yes/no)
• receiving disability payments before their stroke (yes/no)
Sociodemographic Covariates
• Age was categorized into five groups
(<70, 70–74, 75–79, 80–84, 85+ yrs)
• race/ethnicity
(non-Hispanic white, non-Hispanic black, Hispanic, other)
• Whether individuals were receiving coverage from
both Medicaid and Medicare (yes/no)
Higher odds
Lower odds
• In step 1,
• females had higher odds
of reaching an FIM score
of 5 or higher in 14 of 18
FIM items
• and lower odds in 2 of 18
FIM items
• Walking
• was the one FIM item
where the odds ratio
changed
• from favoring females to
not significant.
 Grooming???
Probability of reaching a supervision
level or greater (FIM ≥ 5)
at discharge by sex.
Adjusted values were calculated from
step 2 of the multivariable models
for each functional item.
DISCUSSION
after controlling for other
sociodemographic characteristics and
clinical factors,
females demonstrated greater likelihood
of achieving independence on most
functional items.
Upper limb dressing FIM item is a
harder task for females
• Donning a bra is one of the most
challenging dressing tasks,
• requires fine motor dexterity
• the material is typically elastic and
requires strength from both arms
Stairs is the most challenging lower
limb item on the FIM scale
• males may do better than females after
a stroke secondary to premorbid
strength differences.
• Being physically stronger before the
stroke
These results differ from many previous studies
suggesting that males have better functional outcomes and discharge
disposition than females.
• hospital-based studies tend to find significant sex differences
vs. population-based studies,
• Many studies did not adjust for key covariates, such as age and stroke Severity
• whether a total score or individual scores on a functional measure was used
• age is negatively associated with reaching a supervision level
• Females tend to be older and have more severe strokes.
• females consistently did better on the cognition and communication
FIM items.
Lesion location, which can impact communication and expression deficits,
was not controlled for in this investigation.
• The females and males included in this study had similar usage of
intravenous thrombolysis therapy.
• individuals who lived alone before their stroke did better
than those who lived with family/friends or a caregiver.
• support the importance of interventions that allow individuals to maintain
their physical and cognitive abilities and age in place.
LIMITATIONS
• The impact of sex and previous living arrangement on discharge
destination after rehabilitation was not considered in this investigation
• These results are limited to stroke survivors
• the number of individuals who received tPA could be underreported
• because this medication is typically given while the patient is still in the emergency
department
• not included in the Medicare claims data we used.
• not elucidate the level of involvement of the potential caregivers.
CONCLUSIONS
These results suggest that
maintaining physical and cognitive abilities during the aging process,
regardless of sex,
having the capability to live alone
 could prepare one for better recovery from a stroke.
Thank you for your attention.

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Reha. journal 20200131: The Impact of One’s Sex and Social Living Situation on Rehabilitation Outcomes After a Stroke

  • 1. Journal Reading Presenter: FM R2盧敬文 Supervisor: VS 賴德聰 2020.01.31
  • 2. • important factors associated with stroke treatment and recovery include race/ethnicity, socioeconomic status, and premorbid functional status. • Females tend to be older when they have their stroke • more likely to have hypertension and atrial fibrillation than men.
  • 3. • During acute care, • females are less likely to receive standard of care for stroke management including antiplatelets, statins, and tissue plasminogen activator (tPA) after an ischemic stroke. • Females tend to experience less functional gain during rehabilitation • less likely to be discharged home • less likely to report an identified caregiver.
  • 4. • uses total Scores vs. individual rehabilitation Goals ?  females are more likely to reach their clinician-identified rehabilitation goals • Purpose: examine sex differences in achieving a universally desired rehabilitation outcome— functional independence at discharge and the impact that social living situation has in explaining those differences.
  • 5. METHODS: Data Source Medicare data from the Centers for Medicare and Medicaid Services study was approved by the university’s institutional review board
  • 6. Study Population • ICD-9 codes: hemorrhagic stroke (430–432), ischemic stroke (433–434), acute cerebrovascular diseases ischemic (436), late effects of acute cerebrovascular diseases (438)
  • 7. Independent Variables • sex (male vs. female) • premorbid living arrangement (lived alone, lived with family or spouse, lived with a hired caregiver). Dependent Variables • FIM score at discharge from the IRF. The FIM consists of 18 items in self-care, motor, speech, and cognition categories • Functional independence measure score at discharge for each individual FIM item was dichotomized as ≥5 or <5.
  • 8. Clinical Covariates • Rehabilitation length of stay (LOS) : 4 categories (<10 days, 11–22 days, 23–35 days, >35 days) • Elixhauser Comorbidity Index • uses an extensive list of comorbidities that may interfere with an individual’s progress during rehabilitation (no comorbidities, 1–2 comorbidities, >3 comorbidities) • type of stroke (hemorrhagic,ischemic, other) • tPA treatment during their acute care admission for their stroke (yes/no) • receiving disability payments before their stroke (yes/no)
  • 9. Sociodemographic Covariates • Age was categorized into five groups (<70, 70–74, 75–79, 80–84, 85+ yrs) • race/ethnicity (non-Hispanic white, non-Hispanic black, Hispanic, other) • Whether individuals were receiving coverage from both Medicaid and Medicare (yes/no)
  • 10.
  • 11.
  • 12. Higher odds Lower odds • In step 1, • females had higher odds of reaching an FIM score of 5 or higher in 14 of 18 FIM items • and lower odds in 2 of 18 FIM items • Walking • was the one FIM item where the odds ratio changed • from favoring females to not significant.  Grooming???
  • 13. Probability of reaching a supervision level or greater (FIM ≥ 5) at discharge by sex. Adjusted values were calculated from step 2 of the multivariable models for each functional item.
  • 14. DISCUSSION after controlling for other sociodemographic characteristics and clinical factors, females demonstrated greater likelihood of achieving independence on most functional items.
  • 15. Upper limb dressing FIM item is a harder task for females • Donning a bra is one of the most challenging dressing tasks, • requires fine motor dexterity • the material is typically elastic and requires strength from both arms Stairs is the most challenging lower limb item on the FIM scale • males may do better than females after a stroke secondary to premorbid strength differences. • Being physically stronger before the stroke
  • 16. These results differ from many previous studies suggesting that males have better functional outcomes and discharge disposition than females. • hospital-based studies tend to find significant sex differences vs. population-based studies, • Many studies did not adjust for key covariates, such as age and stroke Severity • whether a total score or individual scores on a functional measure was used • age is negatively associated with reaching a supervision level • Females tend to be older and have more severe strokes.
  • 17. • females consistently did better on the cognition and communication FIM items. Lesion location, which can impact communication and expression deficits, was not controlled for in this investigation. • The females and males included in this study had similar usage of intravenous thrombolysis therapy. • individuals who lived alone before their stroke did better than those who lived with family/friends or a caregiver. • support the importance of interventions that allow individuals to maintain their physical and cognitive abilities and age in place.
  • 18. LIMITATIONS • The impact of sex and previous living arrangement on discharge destination after rehabilitation was not considered in this investigation • These results are limited to stroke survivors • the number of individuals who received tPA could be underreported • because this medication is typically given while the patient is still in the emergency department • not included in the Medicare claims data we used. • not elucidate the level of involvement of the potential caregivers.
  • 19. CONCLUSIONS These results suggest that maintaining physical and cognitive abilities during the aging process, regardless of sex, having the capability to live alone  could prepare one for better recovery from a stroke.
  • 20. Thank you for your attention.