What is the importance of phosphoryl-transfer potential and what factors differentiate the stability of reactants vs. products? Solution Importance of phosphoryl-transfer potential:is defined as the ability of a compound to transfer its phosphoryl group across a membrane.The phosphoryl transfer potential is an important form of cellular energy transformation. 4 factors differentiate the stability of reactants and products: 1. Electrostatic (charge) repulsion. 2. Resonance stabilization. 3. Increase in Entropy. 4.Stabilization due to hydration..