Khyber medical university bio informatics

1. KHYBER MEDICAL UNIVERSITY
BIOINFORMATICS
1.The 1st phase of mitosis is _____________
a) Meta phase b) Ana phase c) Prophase d) Telophase
2.Production of haploid cell occurs in
a) Mitosis b) Meta phase c) Meiosis d) None of these
3.Chromosomes are replicated before
a) Ana phase b) Telophase c) Meiosis d) cytokinesis
4.Production of diploid cell occurs in
a) Mitosis b) Meiosis c) cytokinesis d) Both a & b
5.Cell grows and prepares itself for division in.
a) G1 stage b) S stage c) G2 stage d) All of these
6.Interphase has _____ sub phases.
a) Three b) Four c) Five d) Six
7.The structural and functional unit of DNA is __________________.
a) Genome b) gene c) RNA d) All of them
8.A substantial part of most eukaryotic nuclear genome is made of ______________.
a) recombinant DNA b) repetitive DNA c) both a & b d) None of these
9.Introns are present in the genome of ___________.
a) Prokaryotes b) Eukaryotes c) Bacteria d) None of these
10. Introns are non-coding section of precursor of_____________________.
a) rRNA b) tRNA c) mRNA d) All of them
11.Many of the chromosomes where genes are absent are called ________________.
a) Urban center b) desert center c) Both a & b d) None of these
12.500 kb is equal to.
a) 50000 bytes b) 500000 bytes c) 5000 bytes d) 50 bytes
13.Human genome size spans length of about_________________.
a) 6 feet of DNA b) 7 feet of DNA c) 8 feet of DNA d) 3 feet of DNA
14.The human genome containing about _____________ genes.
a) 30000 to 40000 b) 20000 to 40000 c) 10000 t0 30000 d) 5000 to 10000

2. 15.Human genome project determine the sequence of ____________ bases.
a) 3 billion b) 6 billion base c) 2 billion base d) None of these
16.Human Genome project started in________________ .
a) 1980 b) 1986 c) 1990 d) 2003
17.Human genome project was completed in.
a) 2001 b) 2002 c) 2003 d) 2010
18.____________ part of human genome is repetitive DNA.
a) 50 % b) 60 % c) 55 % d) 20 %
19.Chromosome 1 has the most number of genes are.
a) 2968 b) 2978 c) 3968 d) 231
20.Y chromosome has ________ number of genes.
a) 231 b) 232 c) 233 d) 234
21.E.coli genome having length of about.
a) 4639 kb b) 4739 kb c) 4638 kb d) 6493 kb
22.E.coli genome consists of about _______________ genes.
a) 4266 b) 4288 c) 4388 d) 4488
23.Drosophila melanogaster has genome of about __________ in size.
a) 190Mb b) 180Mb c) 160Mb d) None of these
24.Fruit fly has __________________.
a) 4 chromosomes (2n) b) 4 chromosome (n) c) 6 chromosome (2n) d) None of these
25.Arabidopsis thaliana genome consists of ______________
a) 20 chromosome (2n) b)10 chromosomes (n) c) 10 chromosomes (2n) d) None of these
26.____________ is absent in Animal cells.
a) Cell wall b) cell membrane c) cytoplasm d) nucleus
27.Plants cell contains ____________________.
a) Cell wall b) cell membrane c) cytoplasm d) All of these
28.Nucleus contains __________________.
a) Nuclear envelop b) Chromatin & DNA c) Nucleolus d) All of these
29.Mitochondria consumes ____________.
a) Oxygen b) Carbon dioxide c) Ammonia d) Urea

3. 30.Rough endoplasmic reticulum contains _________________.
a) Ribosomes b) Centriole c) Golgi apparatus d) Co-enzyme
31.Cytosol is a _____________________.
a) Lipid bonded gel b) Protein bonded gel c) water bonded gel d) Carbohydrates bonded gel
32.Most complex and diverse macro-molecule in the cell are.
a) CHOs b) Lipids c) Proteins d) Vitamins
33.The structure of amino acid consists of ______________.
a) COOH group b) Amino group c) Alkyl group d) All of the above
34.Which of the following is purine base.
a) Adenine b) Cytosine c) Thymine d) None of these
35.Which of the following is pyrimidine base.
a) Adenine b) Guanine c) Thymine d) All of these
36.Polarity of H2O allows ______________.
a) H2 bonding b) Ionic bonding c) Covalent bonding d) None of these
37.Hydrophobic molecules are
a) Non-polar b) can't form H bond c) Insoluble d) All of these
38.The centromere is present at the end of ______________ type of chromosome.
a) Acrocentric b) Telocentric c) Sub metacentric d) Telomere
39._____________ is the arrangement of chromosomes from largest to smallest.
a) Karolysis b) Karyotyping c) Karyokinases d) All of these
40.Nucleosome core consists of _____________ histone molecules.
a) 4 b) 9 c) 8 d) 10
41.Chromosomes fragments lacking centromeres are lost in ___________________.
a) Meiosis b) Mitosis c) Both a & b d) None of these
42.Human genome consists of ________________ chromosomes.
a) 40 b) 42 c) 46 d) 48
43.Chimpanzee genome consists of ________________ chromosomes.
a) 46 b) 44 c) 48 d) 30
44.Maize genome consists of ________________ chromosomes.
a) 20 b) 40 c) 46 d) 48

4. 45.__________ are building blocks of proteins.
a) amino acid b) cell c) Tissue d) DNA and RNA
46. In protein amino acids are bound together by __________.
a) Covalent bond b) Peptide bond c) Ionic bond d) Hydrogen bond
47.There primary structure of proteins have ___________ bond.
a) Di-sulphide bond b) Peptide bond c) ionic bond d) Covalent bond
48.Messages are stored in _________ in the form of codons.
a) rRNA b) mRNA c) tRNA d) Smaller nuclear RNA
49.The level of protein in the cell at given time is controlled by ________________.
a) Rate of transcription of the gene b) The efficiency of translation of mRNA into protein
c) The rate of degradation of protein in the cell d) All of these
50.Trypsin break protein into ________.
a) Peptide b) amino acid c) RNA d) None of these
51.The term proteome was first used in.
a) 1999s b) 1990s c) 1996s d) 1991s
52.The study of heredity and variation is called _______.
a) Microbiology b) Anatomy c) Genetics d) Genomics
53.Genetic information is encoded in __________.
a) DNA b) RNA c) rRNA d) mRNA
54._______ has double helical structure.
a) RNA b) Protein c) DNA d) None of these
55.___________change its structure during cell cycle.
a) chromosomes b) Ribosome c)RNA d) All of these
56.Thymine and cytosine have _______ring structure.
a) single b) double c) triple d) None of these
57.Adenine and Guanine have _______ring structure.
a) single b) double c) triple d) None of these
58.James Watsan and Francis Crick proposed the model of _______.
a) RNA b) DNA c) Both a & b d) None of these
59.DNA replication produce ________daughter molecules.

5. a) one b) two c) three d) four
60. In eukaryotes Transcription occurs in ___________.
a) cytoplasm b) Nucleus c) Mitochondria
d) outside the
cell
61._________ occurs in cytoplasm.
a) Transcription b) Translation c) cell division d) all of these
62.During translation mRNA is read in its units of ______nucleotides called codons.
a) 3 b)4 c) 5 d) 6
63.Each codon codes for a specific _________.
a) protein b) amino acid c) carbohydrates d) fats
64.The diploid number is restored at ________.
a) metabolism b) fertilization c) reproduction d) all of these
65.DNA damage that is passed on to subsequent generation is called ______________.
a) Variation b) Mutation c) Radiation d) Both a & b
66.Head is disproportionally small in _________________ disease.
a) Ataxia b) Cockayne’s syndrome c)Bloom’s syndrome d) None of these
67.The longest phase of interphase is ______________.
a) G1 phase b) G2 phase c) S phase d) None of these
68.The study of fundamental relationship between genes proteins and metabolism.
a) Bioinformatics b) Biotechnology c) Biochemical genetics d) All of them
69.The condense form of chromatin is called___________________.
a) Chromosomes b) Genes c) Nucleus d) Ribosomes
70.Uracil is present in ____________________.
a) DNA b) RNA c) Protein d) all of these