This document discusses the use of progestogens in obstetrics, including their absorption, types (natural vs synthetic), and uses. It focuses on threatened miscarriage, recurrent miscarriage, and the prevention of preterm labor. For threatened miscarriage and recurrent miscarriage, oral or vaginal progestogens can reduce miscarriage rates. For preterm labor prevention in singletons, vaginal progesterone is recommended for those with a short cervix, while intramuscular progesterone is used for prior preterm birth history. The evidence for twins is mixed, but vaginal progesterone may help those with a short cervix.