Recommended
More Related Content
Similar to Genetic Mutations dieses A genetic mutation is a change that occurs in our DNA code
Similar to Genetic Mutations dieses A genetic mutation is a change that occurs in our DNA code (20)
Recently uploaded
Recently uploaded (20)
Genetic Mutations dieses A genetic mutation is a change that occurs in our DNA code
- 1. Supervisor: Dr/Asmaa Team leader: Fady Fayez Presenter: Abdalla Gamal Designer: Mohamed Ragab Data collector: Mohamed Nady Summarizer: Hassan
- 2. A genetic mutation is a change that occurs in our DNA code (sequence of nucleotides).
- 3. Internal causes: external causes: 1- Result from errors in DNA replication during cell division. 1- Exposure to mutagens or a viral invasion. 2- Exposed to certain chemicals or radiations.
- 4. deletion insertion inversion translocation
- 5. Deletions are mutations in which a section of DNA is lost, or deleted.
- 6. Insertions are mutations in which extra base pairs are inserted into a new place in the DNA.
- 7. occurs when a section of DNA breaks away from a chromosome during the reproduction and reattaches to the chromosome in reversed order.
- 8. A change in chromosome structure and content caused by translocation.
- 10. A substitution is a mutation that exchanges one base for another (point mutation) or one codon for another.
- 11. Transition Transversio n • Purine replace purine. • Pyrimidine replace. • Pyrimidine. •Purine replace pyrimidine. •Pyrimidine replace purine.
- 12. It is a mutation where one nucleotide is deleted so there is a shift in codon transcription.
- 13. It is a mutation where one nucleotide is inserted so there is a shift in codon transcription.
- 14. • When protein-coding DNA is divided into codons three bases long, insertions and deletions can alter a gene so that its message is no longer correctly parsed. • This usually generates truncated proteins that are useless.
- 15. Silent • mutated codon codes for the same amino acid. • CAA (glutamine) → CAG (glutamine). • Not dangerous. Missense • mutated codon codes for a different amino acid. • CAA (glutamine) → CCA (proline). • May cause diseases. Nonsense • mutated codon is a premature stop codon. • CAA (glutamine) - UAA (stop). • Usually serious.
- 17. • Occurs in gametes. These mutations are especially significant because they can be transmitted to offspring and every cell in the offspring will have the mutation. • Occurs in other cells of the body. These mutations may have little effect on the organism because they are confined to just one cell and its daughter cells. Somatic mutations cannot be passed on to offspring.