how to calculate dose based on various methods!! the types of dose calculations along with some examples. also with some images

1. Prepared by: F.Y.B PHARMACY
•DEEPAK SHUKLA 51
Guided by: DR.SHWETA GUPTA

2. DOSE CALCULATION
• Calculation of adult dose quantity for the children based
on their age , weight or body surface area.
• Also referred as POSOLOGY
The study of dose quantity of a drug.

3. ADULT
Age = above 18 years

4. CLASSIFICATION OF DOSE:
 BASED ON AGE GROUP
 BASED ON WEIGHT
 BASED ON BODY SURFACE AREA(BSA)

5. DOSE BASED ON AGE GROUP
a)Young’s rule
For children having age between 1years –
12 years.
Dose quantity = Age of child in years adult’s
age of child + 12
dose

6. FOR EX:
Age=10 years
Adult’s dose = 150mg
Dose quantity = 10 150
10+12
= 10 150 = 68.2mg
22

7. b) Fried’s rule
It is use to calculate dose for INFANTS
(new born baby) 1-12 months.
Dose quantity = Age in months adult’s
150
dose

8. FOR EX:
Age in months = 10 months
Adult’s dose = 200mg
Dose quantity = 10 200
150
= 2000 = 13.34mg
150

9. c) Dilling’s rule
For the girl having age from 12years-
18years.
Dose quantity = age in years adult’s
20 dose

10. FOR EX:
Age of girl = 15
Adult’s dose = 200mg
Dose quantity = 15 200
20
= 3000 = 150mg
20

11. d) Cowling’s rule
If the age of child is given in years and month
then age at next birthday should be taken.
Dose quantity = age at next birthday adult’s
24
dose

12. FOR EX:
Age = 15 years 6 months = 16 years
Adult’s dose = 240mg
Dose quantity = 16 240
24
= 16 10 = 160mg

13. DOSE BASED ON WEIGHT
The dose quantity based on the weight of the child or
patient.
CLARK’S RULE
IN kg or POUNDS(lbs) 1kg = 2.2 lbs
Dose quantity = weight in kg adult’s dose
68.8kg
= weight in pounds adult’ dose
150 lbs

14. FOR EX:
Weight in kg = 50
Adult’s dose = 200mg
Dose quantity = 50 200
68.8
= 0.73 200
= 145.25mg
Weight in pounds=110lbs
Adult’s dose = 200mg
Dose quantity = 110 200
150
= 0.73 200
= 145.25mg

15. DOSE BASED ON BODY SURFACE
AREA
The dose based on the body surface of a patient i.e:height
and weight.
Dose quantity = patient’s BSA(m2) adult’s dose
1.73
BSA(m2)= height(cm) weight(kg) (m2)
3600

16. FOR EX:
Height = 150cm weight = 50kg
Adult’s dose = 250mg
BSA = 150 50 = 1.44
3600
Dose = 1.44 250 = 208.41mg
1.73
(m2)

17. THANK YOU FOR
YOUR KIND
ATTENTION