2. Acute epiglottitis
Acute inflammatory condition confined to supraglottic
structures (epiglottis, aryepiglottic folds, and arytenoids)
The main causative organism is Haemophilus Influenzae type
B.
Clinical features:
◦ sore throat
◦ Dysphasia and drooling
◦ Odynophagia
◦ dyspnea & stridor
◦ fever ( up to 40 degree)
4. HOW DO YOU MANAGE A PATIENT
WITH ACUTE EPIGLOTTITIS ?
5. At initial presentation
Mask ventilation followed by intubation is
often the first choice.
Tracheotomy/ cricothyrotomy may be
performed in an emergency in patients
who cannot be safely intubated.
Secure airway + supplemental oxygen
6. Third-generation cephalosporins are
preferred as first-line agents because of
increasing resistance to ampicillin.
Ceftriaxone is the antibiotic of choice (DOC)
for epiglottitis.
Intravenous antibiotics
7. • Other antibiotics that can be used:
– Cefotaxime
– ampicillin/sulbactam
– Chloramphenicol
– Cefuroxime
– Vancomycin or clindamycin may be used
in penicillin-allergic patients
8. Dexamethasone: used to reduce supraglottic
inflammation
Used to decrease upper airway mucosal oedema
Corticosteroids
Racemic epinephrine
9. The airway may not be ready for extubation
after 72 hours and continued, prolonged
intubation until the patient meets criteria may be
warranted.
Prolonged Intubation
10. Once stable and extubated
Once the patient is not intubated and tolerating
orals, further antibiotics can be given to be
taken at home
amoxicillin/clavulanate
cefaclor
Oral antibiotics
Editor's Notes
There is marked edema of these structures which may obstruct the airway.