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Professional & Trade Relations Excellence:
                        Optimizing Group Structure & Operations




                                          Best Practices, LLC
                                   Strategic Benchmarking Research



Copyright © Best Practices®, LLC
TABLE OF CONTENTS

               I.     Executive Summary, p. 4-15

               II.    Operational Effectiveness, p. 16-28

               III. Measuring & Communicating Success, p. 29-36

               IV. Challenges & Hurdles for Professional Relations Leaders, p. 37-44

               V.     Organizational Structure, p. 45-51

               VI. Financial & Human Resources, p. 52-60

               VII. Pitfalls, Lessons Learned & Success Factors, p. 61-64

               VIII. About Best Practices, p. 65-66




Copyright © Best Practices®, LLC
Research Objective & Methodology
  Best Practices, LLC conducted this benchmarking research to identify successful industry
  practices and executive insights that biopharmaceutical companies can use to develop a
  strategic Professional and Trade Relations (PTR) function.

          Study Objectives & Methodology                            Key Topics Covered

      Objectives:
      Recognizing changing needs among                  • Professional Relations Operational
      professional and trade groups and a                 Effectiveness
      shifting health care landscape, this study
      seeks to identify PTR benchmark                   • Measuring & Communicating Success
      metrics, industry trends, pitfalls to avoid
      and success factors that lead to effective        • Challenges & Hurdles for Professional
      external collaborations with associations           Relations Leaders
      and societies.
                                                        • Organizational Structure
      Methodology:
      To collect quantitative data, Best                • Financial & Human Resources
      Practices, LLC used an online survey
      instrument. Analysts conducted in-depth           • Pitfalls, Lessons Learned & Success
      interviews to collect executive insights            Factors
      and harvest best practices and lessons
      learned.

Copyright © Best Practices®, LLC                    3
Universe of Learning: 25 Companies Engaged
  Research participants included 26 Professional and Trade Relations executives and
  managers from 25 biopharma and medical device companies across a wide variety of
  therapeutic areas and product classes. Six companies participated in interviews.




                                   Mid-Cap Pharmaceutical Co.




Copyright © Best Practices®, LLC                          4
Director-Level Respondents Dominate Benchmark Class
  Eighty-four percent of the research participants are at a director level. Professional and
  Trade Relations as a function resides in multiple departments and is combined with other
  roles depending on company size, organizational structure and headcount allocation.

                    Respondent Job Level                               Respondent Job Areas
                                                                      • Advocacy
                          Head, 4%    Manager, 4%                     • Advocacy & External Affairs
                                                 Senior
                                                                      • Advocacy & Professional Relations (2)
      Senior/                                  Manager, 8%
                                                                      • Business Analytics & Insights
    Executive
                                                                      • Business Unit Commercial Operations
   Director, 19%
                                                                      • Corporate Communications (2)
                                                        Associate
                                                      Director, 15%
                                                                      • Global Marketing
                                                                      • Government & External Affairs
                                                                      • Grant Management
                                                                      • Marketing (2)
                                                                      • Medical Affairs
                                                                      • Payer Market Development
                                                                      • Product Strategy
                                                                      • Professional Affairs
                                                                      • Professional Relations (4)
                                                                      • Strategic Partnerships
                                                                      • Trade & Distribution
                                                                      • Trade & Specialty
                             Director, 50%
     (n = 26)                                                         • Trade Relations (2)

Copyright © Best Practices®, LLC                         5
Key Insights: Informing Guidelines, Policy & Image
  Professional Trade Relations groups have the opportunity to inform and influence
  guidelines, policy and the company’s reputation to the professional public. This is often
  an advisory role rather than a command-and-control role.


    Influencing and Informing Guidelines: PTR groups often assist in treatment and policy
   Influencing and Informing Guidelines: PTR groups often assist in treatment and policy
    guidelines development by linking product or therapy experts to advocacy
   guidelines development by linking product or therapy experts to advocacy
    organizations involved in the process.
   organizations involved in the process.
    Influencing Corp Brand & Reputation: Savvy PTR groups interact frequently (daily and
   Influencing Corp Brand & Reputation: Savvy PTR groups interact frequently (daily and
    weekly) with their counterparts on corporate branding, social responsibility and other
   weekly) with their counterparts on corporate branding, social responsibility and other
   reputational fronts to help forge positive corporate identities ––communicated to and
    reputational fronts to help forge positive corporate identities communicated to and
    through the professional communities.
   through the professional communities.
    Informing Media Investment for Scientific Branding: Almost half of the benchmark class
   Informing Media Investment for Scientific Branding: Almost half of the benchmark class
    represents the company’s full portfolio of products when communicating with
   represents the company’s full portfolio of products when communicating with
    association partners. PTR groups also advise on key journals and targets for media
   association partners. PTR groups also advise on key journals and targets for media
    investment that helps shape the company’s image among professional, payer and
   investment that helps shape the company’s image among professional, payer and
    patient groups.
   patient groups.
    Exposing Leaders to Leaders: A quarter of PTR groups actively and frequently engage
   Exposing Leaders to Leaders: A quarter of PTR groups actively and frequently engage
    corporate leadership with key association leadership. This represents an opportunity
   corporate leadership with key association leadership. This represents an opportunity
    front for learning, listening and communication at the executive level.
   front for learning, listening and communication at the executive level.


Copyright © Best Practices®, LLC              6
Ad Boards Are Top Activity for Informing Treatment Guidelines
  Professional and Trade Relations may assist in development of treatment guidelines by
  linking product or therapy experts to advocacy organizations involved in the process.
  Only one third of participant groups are not involved in informing treatment guidelines.

      Q23. Which activities does your PTR group do to inform treatment guidelines in your company’s
                          therapeutic focus areas? (Please choose all that apply.)
                                            Treatment Guidelines Activities

                                     Advisory boards                       42%


                       Health Outcomes analysis                           38%


                                   Unrestricted grants                    38%

              PTR group doesn’t take steps to
                                                                         33%
                inform treatment guidelines
                                                                                 Other:
                                        Expert panels               25%          • “Grants are independently
                                                                                   decided by our grant office. Only
                                                                                   medical interacts on clinical
                           Quality of Life analysis                21%             dialogue and for guidelines only in
                                                                                   response to inquiries.”
                                                                                 • “Product developments, e.g. new
                                                Other        13%                   indication”
                                                                                 • “To be determined”
       (n = 24)                                          % Responses

Copyright © Best Practices®, LLC                               7
PTR Aligns with Key Internal Groups through Frequent Interaction
  Frequent communication, at least monthly, with key internal stakeholders ensures
  alignment of goals and messages. Many companies have cross-functional teams that meet
  regularly to update priorities and targets. Respondents also noted daily communication
  with marketing, medical affairs, managed markets, sales, compliance, and finance.
    Q11. Please note the frequency with which you interact with other key internal colleagues/groups to
                                            share and learn.

                                      Daily     Weekly     Monthly    Quarterly   Annually       Never
       Corporate Communications
       – Internal
                                       12%        31%        23%        27%          8%           0%

       Corporate Brand &
       Reputation
                                        8%        38%        19%         8%          12%          15%

       Government Affairs (Federal,
       State or International)
                                        8%        31%        27%        23%          4%           8%

       Policy                           4%        35%        27%        19%          12%          4%
       Corporate Communications
       – External
                                        4%        27%        27%        27%          4%           12%

       Corporate Social
       Responsibility
                                        4%        27%        15%        12%          15%          27%
       (n = 26)
               “Organized interaction is monthly by conference call for professionals within a
               function and semi-annually in a physical meeting.”               - Respondent

Copyright © Best Practices®, LLC                      8
Integrated Portfolio Is Favored PTR Positioning Strategy
  Almost half of the benchmark class is representing the full portfolio of the company’s
  products in communicating with association partners. If a company focuses on a
  particular disease (e.g., diabetes), brand and therapeutic emphasis may intersect.

     Q17. Which statement(s) best describes your corporate positioning strategy with professional and
                       trade relations organizations? (Please check all that apply.)
                                   PTR Corporate Positioning Strategy
              PTR group presents an integrated
                 portfolio of the company’s                             48%
                      brands/products.
          PTR group presents therapeutic area
                                                                32%
                 specific information.

             PTR group presents brand/product
                                                              28%
                   specific information.                              "Our interactions also stress
                                                                      the broader environment that
       PTR group presents information based
                                                                      patients, HCPs, and
         on a company characteristic (e.g.                  24%
                                                                      pharma/bio must operate in
       research-based, patient-focused, etc.).
                                                                      and the importance of
                 No formal corporate positioning                      ensuring HCP-industry
                                                    8%
                            strategy.                                 interactions can continue and
                                                                      that innovation can flourish
                                          Other    4%                 for unmet needs.”
      (n = 25)                                                                         - Respondent

Copyright © Best Practices®, LLC                    9
Portfolio Perspective Provides Benefits over Brand Positioning
  Professional Relations functions can position their companies more strategically with
  association partners when communicating for the full integrated portfolio rather than for
  brands. Representing the entire company allows PTR to “take it up a level.”


                                   Comments from the Field
        “Taking it up a level to the corporate or portfolio level
        allows us to address chronic disease, primary care,
        disparities and other healthcare issues when working
        with our association partners.”


        “When representing all brands, we can roll up lots of little
        grants into one large contribution and potentially become
        a higher level sponsor.”

        “Leverage across all the therapeutic areas if possible.
        Think what it means to work for the whole company not
        just a brand.”

        “Addressing associations at the corporate level instead
        of the brand level creates better long-term partnerships.”

Copyright © Best Practices®, LLC                        10
Only 24% Schedule Regular Meetings with Executive Partners
  PTR leaders touted the importance of executive partnerships but acknowledged the
  challenge of doing them consistently or effectively due to scheduling conflicts and
  executives’ priorities. Our research showed that effective communication can still take
  place in ad-hoc discussions and association gatherings.
     Q18. Which statement best describes your PTR group’s approach to executive level partnerships
    that enable your leadership to discuss policy issues, agendas, and common interests with external
                                           association leaders?

           Occasional meetings to bring VP and
           SVP or “C” Level leaders into contact                       44%
                 with association heads.

         Regularly scheduled meetings to bring
          VP and SVP or “C” Level leaders into               24%
            contact with association heads.

           Ad hoc or informal meetings to bring                    “Regular meetings at conferences
           VP and SVP or “C” Level leaders into          16%       and select regular meetings that
             contact with association heads.                       are quite infrequent (likely annual
                                                                   at best). Meetings can be a full
                                                                   time occupation for all involved
              No approach to such partnerships.          16%       without much specific result if not
                                                                   managed in disciplined way.”
      (n = 25)                                                                            - Respondent

Copyright © Best Practices®, LLC                    11
Executive Partnerships Are Important but Difficult to Engineer
  Although two-thirds of companies fund executive partnerships to build high-level
  relationships with associations, many find program success elusive. The most common
  problem is insufficient motivation/interest/time at the VP level within the corporation.
      Key Objectives of Executive Partner Meetings:
      •   Brief associations on key issues & interests of corporation
      •   Hear key issues & interests of association partners
      •   Identify new opportunities for partnering
      •   Use executive voice to highlight the importance of a key issue

      Failure Points:
      x Insufficient support at the C-suite/Presidential level
                                                                                “Everyone wants to be interacting
      x Not in VP job description/ not measured                                 at the highest levels. Managing
      x Executive schedules are too heavy                                       this is a real challenge.”
      x Not viewed as essential
                                                                                 – Interviewed Associate Director
      x Disconnect over expectations for additional funding
                                                                                “Execs who are high up are not
      Successful Strategies:                                                    looking to sit on an association
                                                                                subcommittee or help with a
          Identify places where the executive can participate with the
          organization and make it meaningful to both parties.                  newsletter. They want an equally
                                                                                high role in the association and
          Consider AVP or Director-level partnerships instead of VP
                                                                                not all of them have that kind of
          Match up corporate & association execs who share specific interests   opportunity.”
          Schedule executive partner meetings at association events
                                                                                           – Interviewed Director
          Invite association execs to corporate headquarters
Copyright © Best Practices®, LLC                            12
About Best Practices, LLC

                  Best Practices, LLC is a research and consulting firm that conducts
                  work based on the simple yet profound principle that organizations
                  can chart a course to superior economic performance by studying
                  the best business practices, operating tactics and winning
                                  strategies of world-class companies.




                                         Best Practices, LLC
                             6350 Quadrangle Drive, Suite 200, Chapel Hill, NC 27517
                                                 919-403-0251
                                           best@best-in-class.com
                                           www.best-in-class.com




Copyright © Best Practices®, LLC

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Professional and Trade Relations Excellence Report Summary

  • 1. Professional & Trade Relations Excellence: Optimizing Group Structure & Operations Best Practices, LLC Strategic Benchmarking Research Copyright © Best Practices®, LLC
  • 2. TABLE OF CONTENTS I. Executive Summary, p. 4-15 II. Operational Effectiveness, p. 16-28 III. Measuring & Communicating Success, p. 29-36 IV. Challenges & Hurdles for Professional Relations Leaders, p. 37-44 V. Organizational Structure, p. 45-51 VI. Financial & Human Resources, p. 52-60 VII. Pitfalls, Lessons Learned & Success Factors, p. 61-64 VIII. About Best Practices, p. 65-66 Copyright © Best Practices®, LLC
  • 3. Research Objective & Methodology Best Practices, LLC conducted this benchmarking research to identify successful industry practices and executive insights that biopharmaceutical companies can use to develop a strategic Professional and Trade Relations (PTR) function. Study Objectives & Methodology Key Topics Covered Objectives: Recognizing changing needs among • Professional Relations Operational professional and trade groups and a Effectiveness shifting health care landscape, this study seeks to identify PTR benchmark • Measuring & Communicating Success metrics, industry trends, pitfalls to avoid and success factors that lead to effective • Challenges & Hurdles for Professional external collaborations with associations Relations Leaders and societies. • Organizational Structure Methodology: To collect quantitative data, Best • Financial & Human Resources Practices, LLC used an online survey instrument. Analysts conducted in-depth • Pitfalls, Lessons Learned & Success interviews to collect executive insights Factors and harvest best practices and lessons learned. Copyright © Best Practices®, LLC 3
  • 4. Universe of Learning: 25 Companies Engaged Research participants included 26 Professional and Trade Relations executives and managers from 25 biopharma and medical device companies across a wide variety of therapeutic areas and product classes. Six companies participated in interviews. Mid-Cap Pharmaceutical Co. Copyright © Best Practices®, LLC 4
  • 5. Director-Level Respondents Dominate Benchmark Class Eighty-four percent of the research participants are at a director level. Professional and Trade Relations as a function resides in multiple departments and is combined with other roles depending on company size, organizational structure and headcount allocation. Respondent Job Level Respondent Job Areas • Advocacy Head, 4% Manager, 4% • Advocacy & External Affairs Senior • Advocacy & Professional Relations (2) Senior/ Manager, 8% • Business Analytics & Insights Executive • Business Unit Commercial Operations Director, 19% • Corporate Communications (2) Associate Director, 15% • Global Marketing • Government & External Affairs • Grant Management • Marketing (2) • Medical Affairs • Payer Market Development • Product Strategy • Professional Affairs • Professional Relations (4) • Strategic Partnerships • Trade & Distribution • Trade & Specialty Director, 50% (n = 26) • Trade Relations (2) Copyright © Best Practices®, LLC 5
  • 6. Key Insights: Informing Guidelines, Policy & Image Professional Trade Relations groups have the opportunity to inform and influence guidelines, policy and the company’s reputation to the professional public. This is often an advisory role rather than a command-and-control role. Influencing and Informing Guidelines: PTR groups often assist in treatment and policy Influencing and Informing Guidelines: PTR groups often assist in treatment and policy guidelines development by linking product or therapy experts to advocacy guidelines development by linking product or therapy experts to advocacy organizations involved in the process. organizations involved in the process. Influencing Corp Brand & Reputation: Savvy PTR groups interact frequently (daily and Influencing Corp Brand & Reputation: Savvy PTR groups interact frequently (daily and weekly) with their counterparts on corporate branding, social responsibility and other weekly) with their counterparts on corporate branding, social responsibility and other reputational fronts to help forge positive corporate identities ––communicated to and reputational fronts to help forge positive corporate identities communicated to and through the professional communities. through the professional communities. Informing Media Investment for Scientific Branding: Almost half of the benchmark class Informing Media Investment for Scientific Branding: Almost half of the benchmark class represents the company’s full portfolio of products when communicating with represents the company’s full portfolio of products when communicating with association partners. PTR groups also advise on key journals and targets for media association partners. PTR groups also advise on key journals and targets for media investment that helps shape the company’s image among professional, payer and investment that helps shape the company’s image among professional, payer and patient groups. patient groups. Exposing Leaders to Leaders: A quarter of PTR groups actively and frequently engage Exposing Leaders to Leaders: A quarter of PTR groups actively and frequently engage corporate leadership with key association leadership. This represents an opportunity corporate leadership with key association leadership. This represents an opportunity front for learning, listening and communication at the executive level. front for learning, listening and communication at the executive level. Copyright © Best Practices®, LLC 6
  • 7. Ad Boards Are Top Activity for Informing Treatment Guidelines Professional and Trade Relations may assist in development of treatment guidelines by linking product or therapy experts to advocacy organizations involved in the process. Only one third of participant groups are not involved in informing treatment guidelines. Q23. Which activities does your PTR group do to inform treatment guidelines in your company’s therapeutic focus areas? (Please choose all that apply.) Treatment Guidelines Activities Advisory boards 42% Health Outcomes analysis 38% Unrestricted grants 38% PTR group doesn’t take steps to 33% inform treatment guidelines Other: Expert panels 25% • “Grants are independently decided by our grant office. Only medical interacts on clinical Quality of Life analysis 21% dialogue and for guidelines only in response to inquiries.” • “Product developments, e.g. new Other 13% indication” • “To be determined” (n = 24) % Responses Copyright © Best Practices®, LLC 7
  • 8. PTR Aligns with Key Internal Groups through Frequent Interaction Frequent communication, at least monthly, with key internal stakeholders ensures alignment of goals and messages. Many companies have cross-functional teams that meet regularly to update priorities and targets. Respondents also noted daily communication with marketing, medical affairs, managed markets, sales, compliance, and finance. Q11. Please note the frequency with which you interact with other key internal colleagues/groups to share and learn. Daily Weekly Monthly Quarterly Annually Never Corporate Communications – Internal 12% 31% 23% 27% 8% 0% Corporate Brand & Reputation 8% 38% 19% 8% 12% 15% Government Affairs (Federal, State or International) 8% 31% 27% 23% 4% 8% Policy 4% 35% 27% 19% 12% 4% Corporate Communications – External 4% 27% 27% 27% 4% 12% Corporate Social Responsibility 4% 27% 15% 12% 15% 27% (n = 26) “Organized interaction is monthly by conference call for professionals within a function and semi-annually in a physical meeting.” - Respondent Copyright © Best Practices®, LLC 8
  • 9. Integrated Portfolio Is Favored PTR Positioning Strategy Almost half of the benchmark class is representing the full portfolio of the company’s products in communicating with association partners. If a company focuses on a particular disease (e.g., diabetes), brand and therapeutic emphasis may intersect. Q17. Which statement(s) best describes your corporate positioning strategy with professional and trade relations organizations? (Please check all that apply.) PTR Corporate Positioning Strategy PTR group presents an integrated portfolio of the company’s 48% brands/products. PTR group presents therapeutic area 32% specific information. PTR group presents brand/product 28% specific information. "Our interactions also stress the broader environment that PTR group presents information based patients, HCPs, and on a company characteristic (e.g. 24% pharma/bio must operate in research-based, patient-focused, etc.). and the importance of No formal corporate positioning ensuring HCP-industry 8% strategy. interactions can continue and that innovation can flourish Other 4% for unmet needs.” (n = 25) - Respondent Copyright © Best Practices®, LLC 9
  • 10. Portfolio Perspective Provides Benefits over Brand Positioning Professional Relations functions can position their companies more strategically with association partners when communicating for the full integrated portfolio rather than for brands. Representing the entire company allows PTR to “take it up a level.” Comments from the Field “Taking it up a level to the corporate or portfolio level allows us to address chronic disease, primary care, disparities and other healthcare issues when working with our association partners.” “When representing all brands, we can roll up lots of little grants into one large contribution and potentially become a higher level sponsor.” “Leverage across all the therapeutic areas if possible. Think what it means to work for the whole company not just a brand.” “Addressing associations at the corporate level instead of the brand level creates better long-term partnerships.” Copyright © Best Practices®, LLC 10
  • 11. Only 24% Schedule Regular Meetings with Executive Partners PTR leaders touted the importance of executive partnerships but acknowledged the challenge of doing them consistently or effectively due to scheduling conflicts and executives’ priorities. Our research showed that effective communication can still take place in ad-hoc discussions and association gatherings. Q18. Which statement best describes your PTR group’s approach to executive level partnerships that enable your leadership to discuss policy issues, agendas, and common interests with external association leaders? Occasional meetings to bring VP and SVP or “C” Level leaders into contact 44% with association heads. Regularly scheduled meetings to bring VP and SVP or “C” Level leaders into 24% contact with association heads. Ad hoc or informal meetings to bring “Regular meetings at conferences VP and SVP or “C” Level leaders into 16% and select regular meetings that contact with association heads. are quite infrequent (likely annual at best). Meetings can be a full time occupation for all involved No approach to such partnerships. 16% without much specific result if not managed in disciplined way.” (n = 25) - Respondent Copyright © Best Practices®, LLC 11
  • 12. Executive Partnerships Are Important but Difficult to Engineer Although two-thirds of companies fund executive partnerships to build high-level relationships with associations, many find program success elusive. The most common problem is insufficient motivation/interest/time at the VP level within the corporation. Key Objectives of Executive Partner Meetings: • Brief associations on key issues & interests of corporation • Hear key issues & interests of association partners • Identify new opportunities for partnering • Use executive voice to highlight the importance of a key issue Failure Points: x Insufficient support at the C-suite/Presidential level “Everyone wants to be interacting x Not in VP job description/ not measured at the highest levels. Managing x Executive schedules are too heavy this is a real challenge.” x Not viewed as essential – Interviewed Associate Director x Disconnect over expectations for additional funding “Execs who are high up are not Successful Strategies: looking to sit on an association subcommittee or help with a Identify places where the executive can participate with the organization and make it meaningful to both parties. newsletter. They want an equally high role in the association and Consider AVP or Director-level partnerships instead of VP not all of them have that kind of Match up corporate & association execs who share specific interests opportunity.” Schedule executive partner meetings at association events – Interviewed Director Invite association execs to corporate headquarters Copyright © Best Practices®, LLC 12
  • 13. About Best Practices, LLC Best Practices, LLC is a research and consulting firm that conducts work based on the simple yet profound principle that organizations can chart a course to superior economic performance by studying the best business practices, operating tactics and winning strategies of world-class companies. Best Practices, LLC 6350 Quadrangle Drive, Suite 200, Chapel Hill, NC 27517 919-403-0251 best@best-in-class.com www.best-in-class.com Copyright © Best Practices®, LLC