Today around 47 million people survive with dementia, globally. This number is projected to increase to more than 131 million by 2050. About 2.1 million Alzheimer's patients having age of 85 years or older were reported in year 2017.

1. ANTIBODIES FOR
ALZHEIMER’S DISEASE
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2. ABOUT
CREATIVE BIOLABS
Creative Biolabs is the leading antibody service provider with
extensive experience in a variety of antibody production and
engineering field for both basic science research and
pharmaceutic industries. We offer high quality ready-to-use
catalogue antibodies, as well as flexible and comprehensive
customized services for the antibody production. With high
level professional scientists and advanced antibody production
platform, we are dedicated to offering various antibodies for a
wide range of applications, and designing a specific antibody
project to tailor the best service to best fit your requirements.
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3. Introduction
Today around 47 million people survive with dementia, globally. This number is
projected to increase to more than 131 million by 2050. About 2.1 million
Alzheimer's patients having age of 85 years or older were reported in year
2017. Alzheimer's disease (AD) is one of the most common multifactorial
diseases, including a range of abnormal cellular/molecular processes occurring
in different regions of the brain. This disease is considered to be a major
contributor to dementia in the elderly people. The pathophysiology involves
accumulation of extracellular plaques containing the β-amyloid protein which
is generated by the breakdown of the β-amyloid precursor protein (APP) in the
brain. Another mechanism involves formation of intracellular neurofibrillary
tangles of hyperphosphorylated tau protein. The AD can be classified into two
types, familial AD (FAD) and sporadic AD (SAD) based on heritability apart from
this the early-onset AD (EOAD) and late-onset AD (LOAD) forms are based on
the age of onset. Some proteins, such as APOE, APP, BACE (b-amyloid cleaving
enzyme), secretases, PS1/2 and tau proteins are reported in AD brain and have
been correlated with disease. It is still unclear whether this disease comprises
genetic or environmental factors or both.
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4. Hypothetical model of AD pathophysiology
(Pathophysiological pathway and Amyloidgenic
pathway)
Pathophysiology and factors (Mutations,
NFT, Oxidative stress, mitochondrial
dysfunction) involved in AD
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5. Alzheimer's
Disease
Pathway
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6. Alzheimer’s Disease Therapeutic Targets
Name of target Source Functions
Amyloid protein precursor (APP) Hippocampus, olfactory bulb Formation of Aβ
Muscarinic acetylcholine receptor (mAchR) Hippocampus Hyperphosphorylation of tau protein
Nicotinergic acetylcholine receptor (nAChR) Cerebral cortex
Cognitive, memory function and also involve in progression
of sensory information
Triggering receptor expressed on myeloid cells 2 (TREM2) Myeloid cells amyloid pathology
Calcitonin gene- regulated peptide (CGRP)
Hypothalamus, ventromedial nucleus of the
thalamus, amygdala, grey matter, hippocampus
and denate gyrates
Neurotransmitter
C-C chemokine receptor type-5 (CCR5) Cortical neurons, hippocampal Recruitment of leukocytes to inflammatory sites
β-Secretase: Aspartyl Proteases(BACE) Astrocyte Formation of Aβ
γ-Secretase: Presenilin I (PSEN1) Medial temporal lobe cortex Formation of Aβ
Protein tyrosine phosphatase 1B (PTP1B) Hippocampal, microglial
Learning, memory, endoplasmic reticulum, stress,
regulation of synapse dynamics and microglial mediated
Neuroinflammation.
Nuclear facto r E2 related factor-2 (Nrf2) Temporal lobe, microglia and astrocytes
Antioxidant
Maintaining redox balance and eliminate damage proteins
Butyrylcholinesterase (BCHE) Basal forebrain Neuritic plaques and neurofibrillary tangles
Phosphodisterase (PDE) Hippocampus, Cortex stratium Hydrolysis of CGMP
N-myc downstream-regulated gene 2 (NDRG2) Astrocytes, glia cells Differentiation, cell proliferation and cell apoptosis
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7. Alzheimer’s Disease Therapeutic Targets
Name of target Source Functions
Serotonin 5-HT6 receptor Cortical Improving cognition dysfunction, synaptic plasticity
Gama aminobutyric Acid A receptor (GABA)
Cerebral cortex, temporal lobes, frontal and
occipital lobes
Neurotransmitter in cerebral cortex
Monoamine oxidase B (MAO-B)
Astrogila, hippocampus, cerebral cortex and
astrocyte
Metabolism of monoamine neurotransmitter
NAD (P)H Quinone oxidoreductase 1 (NADPHQ1) Oxidative stress, abnormality in redox balance
Neurotrophic Receptor Tyrosine Kinase 1 (NRTK1) Basal forebrain Nucleus Basalis (NB) Development of CNS and PNS, promotion of cell survival
Gamma-secretase metabotropic glutamate receptor Cortical and Hippocampal Releasing of ca2+
Peroxisome proliferator activated receptor-γ (PPARs) Astrocytes and microglial cells
Lipid storage, adipocyte differentiation, and lipid storage and
glucose homeostasis
CP-AMPARs Hippocampi Boost synaptic Ca2+
Parkinson disease protein 7(DJ-1/PARK7) Hippocampus
Antioxidant, molecular chaperon, protein degeneration and
transcriptional regulation
Angiotensin receptor
Astrocyte, neurons, microlia and cerebrovascular
endothelial cells
Anti-inflammatory compounds
synaptic signalling
Non-amyloid-beta component precursor (NACP)
Neocortex, hippocampus, olfactory bulb,
Striatum, thalamus, and cerebellum
Amyloidogenesis and plaque formation
c-Jun N-terminal kinases (JNK) Cortex hippocampus and cerebellum Neuronal apoptosis, neural tube defects and oxidative stress
Dopamine 2 receptor Central nervous system Aβ plaques
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8. Amyloid protein
precursor (APP)
Amyloidgenic process of APP hypothesis and formation of Aβ-42. APP
protein can be processed by different enzymes like β-secretase, γ-
secretase and α- secretase. sAPPβ and sAPPα is produced with
peptides C83 and C99.
Human APP gene was first discovered in 1987 from β-amyloid and
the gene was mapped to chromosome 21. APP belongs to membrane
proteins containing extracellular domain and short cytoplasmic
region. APP releases Aβ by two cleavage processes, one in the
extracellular domain (β-secretase cleavage) and another one in the
transmembrane region (γ-secretase cleavage). Different types of APP
proteins can be formed by alternative splicing from the single gene.
APP695 is a major splice form in neurons. APP is cleaved by two
different proteolytic pathways, one is a non-Amyloidogenic and other
one is Amyloidogenic pathway. For this process, two main enzymes γ-
secretase and β-secretase are responsible.
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9. APP Antibodies
Target Cat Product Name Clone Host Species Reactivity Application
APP TAB-225 Anti-Human Abeta Antibody (Bapineuzumab) Bapineuzumab Mouse Human
WB, FuncS, IF, Neut,
ELISA, FC, IP
APP TAB-226 Anti-Human Abeta Antibody (Crenezumab) Crenezumab Mouse Human
WB, IF, IP, Neut, FuncS,
ELISA, FC
APP TAB-227 Anti-Human Abeta Antibody (Ponezumab) Ponezumab Mouse Human
WB, ELISA, IP, FC,
FuncS, Neut, IF
APP TAB-228 Anti-Human Abeta Antibody (Solanezumab) Solanezumab Mouse Human
WB, FuncS, IF, Neut,
ELISA, FC, IP
APP PABL-404
Recombinant Mouse Anti-APP Antibody
(WO2)
WO2 Mouse Human WB, ELISA, FuncS
APP TAB-229
Anti-Human Abeta Antibody
(Gantenerumab)
Gantenerumab Human Human
FuncS, IF, Neut, ELISA,
FC, IP, ICC
APP PABL-011
Recombinant Mouse Anti-APP Antibody
(3D6)
3D6 Mouse Human WB, ELISA, FuncS
APP PABL-012
Recombinant Human Anti-APP Antibody
(9TL)
9TL Human Human WB, FuncS
APP PABL-013
Recombinant Mouse Anti-APP Antibody
(C705)
C705 Mouse Human WB, ELISA, FuncS
APP PABL-401
Recombinant Mouse Anti-APP Antibody
(10D5)
10D5 Mouse Human WB
APP PABL-403
Recombinant Mouse Anti-APP Antibody
(c706)
c706 Mouse Human ELISA
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10. APP Antibodies
Target Cat Product Name Clone Host Species Reactivity Application
APP HPAB-0008-YJ
Recombinant Mouse Anti-APP Antibody
(508F)
508F Mouse Human ELISA
APP HPAB-0105-YJ
Recombinant Humanized Anti-APP
Antibody (hu5E3)
hu5E3 Human Human ELISA, WB
APP HPAB-0117CQ
Recombinant Human Anti-APP Antibody
(Hu15C11)
Hu15C11 Human Human ELISA, WB, IP, FuncS
APP HPAB-0118CQ
Recombinant Human Anti-APP Antibody
(Fv1E4)
Fv1E4 Human Human ELISA, Inhib
APP HPAB-0119CQ
Recombinant Human Anti-APP Antibody
(h12A11v1)
h12A11v1 Human Human ELISA, FuncS
APP HPAB-0121CQ
Recombinant Mouse Anti-APP Antibody
(MAB 2.1)
MAB 2.1 Mouse Human ELISA, IHC, FuncS
APP HPAB-0176-FY
Recombinant Mouse Anti-APP Antibody
(5C9)
5C9 Mouse Human AG
APP HPAB-0242-FY
Recombinant Human Anti-APP Antibody
(BBS3/F5.100)
BBS3/F5.10
0
Human Human WB
APP HPAB-0255-YJ
Recombinant Human Anti-APP Antibody
(CBA45YJ)
CBA45YJ Human Human ELISA, WB, Inhib, FuncS
APP PABW-009
Recombinant Mouse Anti-APP Antibody
(PFA1)
PFA1 Mouse Human ELISA
APP PABX-014
Recombinant Rabbit Anti-APP Antibody
(M204)
M204 Rabbit Human WB, ELISA, FuncS
APP PABL-404
Recombinant Mouse Anti-APP Antibody
(WO2)
WO2 Mouse Human WB, ELISA, FuncS
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11. Beta-amyloid Antibodies
Target Cat Product Name Clone Host Species Reactivity Application
Aβ1-40 + Aβ1-42 HPAB-0871-CN
Recombinant Mouse Anti-Aβ1-40 + Aβ1-42 Antibody
(AL-217)
AL-217 Mouse Human ELISA, Dot, Neut
Aβ1-40 + Aβ1-42 HPAB-0872-CN
Recombinant Mouse Anti-Aβ1-40 + Aβ1-42 Antibody
(AL-224)
AL-224 Mouse Human ELISA, Dot, Neut
Aβ1-40 + Aβ1-42 HPAB-0873-CN
Recombinant Mouse Anti-Aβ1-40 + Aβ1-42 Antibody
(AL-225)
AL-225 Mouse Human ELISA, Dot, Neut
Aβ42
FAMAB-
0023YC
Recombinant Mouse Anti-Aβ42 Antibody (AM 2.9) AM 2.9 Mouse Human ELISA
Aβ42
FAMAB-
0024YC
Recombinant Mouse Anti-Aβ42 Antibody (AM 3.26) AM 3.26 Mouse Human ELISA
Aβ42
FAMAB-0148-
CN
Recombinant Human Anti-Aβ42 Antibody (AS) AS Human Human WB
Aβ42
FAMAB-0160-
CN
Recombinant Human Anti-Aβ42 Antibody (scFv59) scFv59 Human Human
WB, ELISA, IF,
IHC
Aβ42 HPAB-0511-WJ
Recombinant Mouse Anti-Aβ42 peptide Antibody
(3F5)
3F5 Mouse Human ELISA, FC
Aβ42
HPAB-AP849-
YC
Recombinant Mouse Anti-Aβ 42 Antibody
(AP017/YC)
AP017/YC Mouse Human ELISA, Dot
Aβ 1-42
HPAB-M0417-
YC
Recombinant Human Anti-Aβ 1-42 Antibody
(Abet0369)
Abet0369 Human Human ELISA, Inhib
Aβ 1-42
HPAB-M0420-
YC
Recombinant Human Anti-Aβ 1-42 Antibody
(Abet0382)
Abet0382 Human Human ELISA, Inhib
Aβ 1-42
HPAB-M0421-
YC
Recombinant Human Anti-Aβ 1-42 Antibody
(Abet0380-GL)
Abet0380-
GL
Human Human ELISA, WB, Inhib
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12. Beta-amyloid Antibodies
Target Cat Product Name Clone Host Species Reactivity Application
Beta-amyloid HPAB-0339LY
Recombinant Humanized Anti-Beta-amyloid
Antibody (hC2)
hC2 Humanized Human ELISA, IHC
Beta-amyloid HPAB-0958WJ
Recombinant Human Anti-Beta-amyloid
Antibody (LP09027)
LP09027 Human Human ELISA
Amyloid HPAB-J0035-YC
Recombinant Mouse Anti-Amyloid Antibody
(A8)
A8 Mouse Human
ELISA, IHC, WB,
FuncS
Amyloid beta HPAB-0850LY
Recombinant Mouse Anti-Amyloid beta
Antibody (7E7)
7E7 Mouse Human ELISA
Amyloid beta HPAB-0851LY
Recombinant Mouse Anti-Amyloid beta
Antibody (6C2)
6C2 Mouse Human ELISA
Amyloid beta HPAB-1131WJ Recombinant Mouse Anti-Aβ Antibody (4396C) 4396C Mouse Human ELISA
Amyloid beta HPAB-1135WJ Recombinant Human Anti-Aβ Antibody (h10D5) h10D5 Human Human ELISA
Amyloid beta HPAB-1157WJ Recombinant Human Anti-Aβ Antibody (266) 266 Human Human ELISA
Aβ 4-40 HPAB-AP254-YC
Recombinant Mouse Anti-Aβ 4-40 Antibody
(NT4X-167)
NT4X-167 Mouse Human ELISA, Inhib
Aβ 4-40 HPAB-AP255-YC
Recombinant Mouse Anti-Aβ 4-40 Antibody
(NT4X-83)
NT4X-83 Mouse Human ELISA, Inhib
Aβ oligomer HPAB-1066WJ
Recombinant Human Anti-Aβ oligomer
Antibody (h4H5)
h4H5 Human Human ELISA
Aβ oligomer HPAB-0256-YJ
Recombinant Humanized Anti-Aβ oligomer
Antibody (6E4HV0LV0)
6E4HV0LV0 Human Human FuncS
Aβ42-CC
oligomer
HPAB-0100CQ
Recombinant Mouse Anti-Aβ42-CC oligomer
Antibody (mAb20)
mAb20 Mouse Human ELISA, IHC
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13. AChR Antibodies
Target Cat Product Name Clone Host Species Reactivity Application
AChR CBMAB-082CQ Mouse Anti-AChR Antibody (mAb192) mAb192 Mouse Human, Mouse, Rat ELISA, WB, BL
AChR MHH-33 Recombinant Human Anti-AChR Antibody Human Human
ELISA, WB, IP,
FuncS
AChR FAMAB-0224YC Recombinant Rat Anti-AChR Antibody (mAb195) mAb195 Rat Human FuncS
AChR PABC-007 Recombinant Rat Anti-AChR Antibody (mAb192) mAb192 Rat Human WB, FuncS
AChR PABZ-007 Recombinant Rat Anti-AChR Antibody (mAb198) mAb198 Rat Human WB, ELISA
AChR TAB-0636CLV Anti-Human AChR Antibody (P90-131) P90-131 Human Human WB, ELISA
AChR TAB-0637CLV Anti-Human AChR Antibody (P90-65) P90-65 Human Human WB, ELISA
AChR TAB-0638CLV Anti-Human AChR Antibody (IgG1-637) IgG1-637 Human Human WB, ELISA
AChR TAB-0639CLV Anti-Human AChR Antibody (IgG4-637) IgG4-637 Human Human WB, ELISA
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14. APOE Antibodies
Target Cat Product Name Clone Host Species Reactivity Application
APOE HPAB-0115CQ Recombinant Mouse Anti-APOE Antibody (2E8) 2E8 Mouse Human ELISA, BL
APOE HPAB-N0315-YC
Recombinant Mouse Anti-APOE Antibody
(HJ156)
HJ156 Mouse Human ELISA, WB
APOE HPAB-N0316-YC
Recombinant Mouse Anti-APOE Antibody
(HJ151)
HJ151 Mouse Human ELISA, WB
APOE HPAB-N0317-YC
Recombinant Mouse Anti-APOE Antibody
(HJ153)
HJ153 Mouse Human IP, ELISA, WB
APOE MOB-0669MZ
Recombinant Mouse Anti-Human APOE
Antibody (clone F7E8)
F7E8 Mouse Human
ELISA, IHC-Fr, IHC-P,
IP, WB
APOE MOR-0215
Hi-Affi™ Recombinant Rabbit Anti-APOE
Monoclonal Antibody (DS215AB)
DS215AB Rabbit Human FC, IHC-P, IP, WB
APOE MOR-4534
Hi-Affi™ Recombinant Rabbit Anti-APOE
Monoclonal Antibody (TH42DS)
TH42DS Rabbit
Human, Mouse,
Rat
WB, IF, ICC
APOE TAB-0963CLV Anti-Human APOE Antibody (807A-M0028-B02)
807A-M0028-
B02
Human Human ELISA
APOE TAB-0964CLV Anti-Human APOE Antibody (807B-M0004-A03)
807B-M0004-
A03
Human Human ELISA
APOE TAB-0965CLV Anti-Human APOE Antibody (807B-M0004-H03)
807B-M0004-
H03
Human Human ELISA
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15. Tau Antibodies
Target Cat Product Name Clone Host Species Reactivity Application
MAPT HPAB-0198-YJ
Recombinant Mouse Anti-MAPT Antibody
(13A6)
13A6 Mouse Human, Monkey Immunoassay, IP
MAPT HPAB-0485-FY
Recombinant Mouse Anti-MAPT Antibody
(6B2G12)
6B2G12 Mouse Human WB, IP
MAPT PABL-340 Recombinant Mouse Anti-TAU Antibody (AT8) AT8 Mouse Human ELISA, FuncS
MAPT PABC-456
Recombinant Mouse Anti-MAPT Antibody
(chCBTAU-22.1)
chCBTAU-22.1 Mouse Human ELISA, WB, IHC, FC
MAPT PABC-454
Recombinant Mouse Anti-MAPT Antibody
(chCBTAU-7.1)
chCBTAU-7.1 Mouse Human ELISA, WB, IHC, FC
MAPT PABC-452
Recombinant Human Anti-MAPT Antibody
(dmCBTAU-27.1)
dmCBTAU-27.1 Human Human ELISA, WB, IHC, Inhib
MAPT HPAB-0042-WJ
Recombinant Human Anti-MAPT Antibody
(hACI-36-2B6-Ab1)
hACI-36-2B6-Ab1 Human Human ELISA, WB
MAPT NS-090CN
Recombinant Mouse Anti-MAPT Antibody
(HJ8.5)
HJ8.5 Mouse Human WB, ELISA, IHC, IP
MAPT HPAB-N0171-YC
Recombinant Human Anti-MAPT Antibody
(hu37D3.v28.A4 hIgG4-S228P.YTE)
hu37D3.v28.A4
hIgG4-S228P.YTE
Human Human ELISA, FuncS
MAPT HPAB-0093-FY
Recombinant Human Anti-MAPT Antibody (NI-
105.4A3)
NI-105.4A3 Human Human WB, ELISA
MAPT HPAB-0099-WJ
Recombinant Human Anti-MAPT Antibody (NI-
105.6C5)
NI-105.6C5 Human Human ELISA, FC
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16. Tau Antibodies
Target Cat Product Name Clone Host Species Reactivity Application
MAPT HPAB-N0170-YC
Recombinant Humanized Anti-MAPT Antibody
(NOV018YC)
NOV018YC Human Human ELISA, Inhib
MAPT HPAB-0108-WJ
Recombinant Rabbit Anti-MAPT Antibody
(Otau(S400))
Otau(S400) Rabbit Human ELISA
MAPT HPAB-0106-WJ
Recombinant Human Anti-MAPT Antibody (TAM-
1)
TAM-1 Human Human ELISA, WB
MAPT HPAB-0029-WJ Recombinant Mouse Anti-MAPT Antibody (PT3) PT3 Mouse Human ELISA, WB
MAPT HPAB-0484-FY
Recombinant Mouse Anti-MAPT Antibody
(scFv235)
scFv235 Mouse Human WB, IP
Tau TAB-524CT
Anti-Human Oligomeric tau Therapeutic Antibody
(F9T)
F9T Mouse Human WB, ELISA, IHC
Tau TAB-526CT
Anti-Human Oligomeric tau Therapeutic Antibody
(H2A)
H2A Mouse Human WB, ELISA, IHC
Tau TAB-538CT Anti-Human Tau Therapeutic Antibody (2.20.4) 2.20.4 Mouse Human ELISA, IF
Tau TAB-529CT Anti-Human Tau Therapeutic Antibody (2H9) 2H9 Mouse Human
WB, ELISA, IF,
IHC
Tau TAB-527CT Anti-Human Tau Therapeutic Antibody (16B5) 16B5 Humanized Human WB, ELISA, IHC
Tau TAB-519CT Anti-Human Tau Therapeutic Antibody (1F12C2) 1F12C2 Mouse Human WB, ELISA
Tau TAB-533CT Anti-Human Tau Therapeutic Antibody (DC8E8) DC8E8 Humanized Human
WB, ELISA, IP,
IHC, Neut
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17. Tau Antibodies
Target Cat Product Name Clone Host Species Reactivity Application
Tau TAB-521CT Anti-Human Tau Therapeutic Antibody (4E6E3) 4E6E3 Mouse Human WB, ELISA
Tau TAB-536CT Anti-Human Tau Therapeutic Antibody (ADx201) ADx201 Mouse Human WB, ELISA, IHC
Tau TAB-525CT
Anti-Human Oligomeric tau Therapeutic Antibody
(D11C)
D11C Mouse Human WB, ELISA, IHC
Tau TAB-532CT
Anti-Human Tau Therapeutic Antibody
(pS396/pS404_1)
pS396/pS404_1 Chicken Human WB, ELISA, IP, IHC
Tau TAB-531CT
Anti-Human Tau Therapeutic Antibody
(pT212/pS214_2)
pT212/pS214_2 Chicken Human WB, ELISA, IP, IHC
MAPT PABL-680
Recombinant Chicken Anti-phospho-tau Antibody
(pT231/pS235_1)
pT231/pS235_1 Chicken Human
WB, ELISA, FACS,
BL
MAPT
(pS396)
HPAB-N0175-
YC
Recombinant Human Anti-MAPT (pS396) Antibody
(hC10-2_N32S_A101T)
hC10-
2_N32S_A101T
Human Human Dot, WB, Inhib, IP
MAPT
(pS422)
HPAB-0300-YJ
Recombinant Humanized Anti-MAPT (pS422)
Antibody (hu 086)
hu 086 Human Human FC, ELISA, IF
Phosphoryla
ted Tau
TAB-0430CL
Anti-Human Phosphorylated Tau Therapeutic
Antibody (Ta1501)
Ta1501 Mouse Human ELISA, FuncS
Phosphoryla
ted Tau
TAB-0437CL
Anti-Human Phosphorylated Tau Therapeutic
Antibody (Ta9)
Ta9 Mouse Human ELISA, FuncS
Hyperphosp
horylated
Tau (pS396)
HPAB-2331LY
Recombinant Humanized Anti-
Hyperphosphorylated Tau (pS396) Antibody (D1.2)
D1.2 Humanized Human
Dot, WB, Inhib,
ELISA
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18. BACE1 Antibodies
Target Cat Product Name Clone Host Species Reactivity Application
BACE1 HPAB-0285-YC Recombinant Mouse Anti-BACE1 Antibody (5H10) 5H10 Mouse Human ELISA, FuncS
BACE1 HPAB-0672-CN Recombinant Mouse Anti-BACE1 Antibody (M2-1003) M2-1003 Mouse Human
ELISA, FC, IHC,
Neut
BACE1 HPAB-0673-CN Recombinant Mouse Anti-BACE1 Antibody (M2-1000) M2-1000 Mouse Human
ELISA, FC, IHC,
Neut
BACE1 MOR-0315
Hi-Affi™ Recombinant Rabbit Anti-BACE1
Monoclonal Antibody (DS315AB)
DS315AB Rabbit Human WB, IP
BACE1 NEUT-036CQ Recombinant Mouse Anti-BACE1 Antibody (CBL278) CBL278 Mouse Human, Mouse ELISA, IP, Neut
BACE1 NEUT-037CQ Recombinant Mouse Anti-BACE1 Antibody (CBL696) CBL696 Mouse Human, Mouse IP, Neut
BACE1 PABL-408
Recombinant Human Anti-BACE1 Antibody
(YW412.8.31)
YW412.8.31 Human Human ELISA, BL, Neut
BACE1 TAB-1153CL Anti-Human BACE1 Antibody (2G3) 2G3 Mouse Human ELISA
BACE1 TAB-1154CL Anti-Human BACE1 Antibody (5G7) 5G7 Mouse Human ELISA
BACE1 TAB-1155CL Anti-Human BACE1 Antibody (14F10) 14F10 Mouse Human ELISA
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19. SNCA Antibodies
Target Cat Product Name Clone Host Species Reactivity Application
SNCA CBMAB-090LC
Recombinant Human Anti-SNCA
Therapeutic Antibody (aSynA)
aSynA Human Human ELISA, FuncS, WB
SNCA FAMAB-0260-CN
Recombinant Human Anti-SNCA Antibody
(D10)
D10 Human Human ELISA
SNCA FAMAB-0261-CN
Recombinant Human Anti-SNCA Antibody
(6E)
6E Human Human ELISA
SNCA FAMAB-0262-CN
Recombinant Human Anti-SNCA Antibody
(4B)
4B Human Human ELISA
SNCA FAMAB-0263-CN
Recombinant Human Anti-SNCA Antibody
(3E)
3E Human Human ELISA
SNCA HPAB-0023-FY
Recombinant Mouse Anti-SNCA Antibody
(49/G)
49/G Mouse Human ELISA
SNCA HPAB-0033-YC
Recombinant Human Anti-SNCA Antibody
(NI-202.12F4)
NI-202.12F4 Human Human
ELISA, WB, IHC,
FuncS
SNCA HPAB-0034-YC
Recombinant Human Anti-SNCA Antibody
(NI-202.3G12)
NI-202.3G12 Human Human ELISA, WB
SNCA HPAB-0035-YC
Recombinant Human Anti-SNCA Antibody
(NI-202.3D8)
NI-202.3D8 Human Human ELISA, WB
SNCA HPAB-0328-YJ
Recombinant Humanized Anti-SNCA
Antibody (h5C1)
h5C1 Human Human ELISA, WB
SNCA HPAB-0368LY
Recombinant Mouse Anti-SNCA Antibody
(9E4)
9E4 Mouse Human IP, WB
SNCA HPAB-653-FY
Recombinant Mouse Anti-SNCA Antibody
(38E2/7)
38E2/7 Mouse Human WB, IP, ELISA
SNCA HPAB-654-FY
Recombinant Mouse Anti-SNCA Antibody
(38Fll/2_8)
38Fll/2_8 Mouse Human ELISA
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20. SNCA Antibodies
Target Cat Product Name Clone Host
Species
Reactivity
Application
SNCA HPAB-AP186-YC
Recombinant Mouse Anti-SNCA Antibody
(m1H7)
m1H7 Mouse Human FuncS
SNCA HPAB-AP188-YC
Recombinant Humanized (Human/Mouse) Anti-
SNCA Antibody (1H7 H3L3)
1H7 H3L3 Human Human FuncS
SNCA HPAB-M0696-YC
Recombinant Mouse Anti-SNCA Antibody
(IGP101)
IGP101 Mouse Human ELISA, FuncS
SNCA HPAB-N0389-YC
Recombinant Humanized Anti-SNCA Antibody
(2E6-HDL1)
2E6-HDL1 Human Human ELISA, IP, FuncS
SNCA HPAB-N0390-YC
Recombinant Mouse Anti-SNCA Antibody
(m2E6)
m2E6 Mouse Human ELISA, IP, FuncS
SNCA MOB-0599MZ
Recombinant Mouse Anti-Human SNCA
Antibody (clone 20D4)
20D4 Mouse Human ELISA, WB
SNCA MOR-0154
Hi-Affi™ Recombinant Rabbit Anti-alpha + beta
Synuclein Monoclonal Antibody (DS154AB)
DS154AB Rabbit
Mouse, Rat,
Human
FC, WB, ICC/IF
SNCA MOR-3354
Hi-Affi™ Recombinant Rabbit Anti-SNCA
Monoclonal Antibody (DS3354AB)
DS3354AB Rabbit Human IHC, ICC, FC, IP
SNCA MOR-4530
Hi-Affi™ Recombinant Rabbit Anti-SNCA
Monoclonal Antibody (TH38DS)
TH38DS Rabbit Human WB, IF, ICC, IHC-P, FC
SNCA NEUT-1977CQ
Recombinant Human Anti-SNCA Antibody
(NAC32)
NAC32 Human Human IHC, WB, BL
SNCA NS-005CN Recombinant Mouse Anti-SNCA Antibody (13F3) 13F3 Mouse
Human,
Mouse
WB, ELISA, FC
SNCA NS-088CN Recombinant Mouse Anti-SNCA Antibody (1F7) 1F7 Mouse Human WB, ELISA, IHC
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21. TREM2 Antibodies
Target Cat Product Name Clone Host Species Reactivity Application
TREM2 HPAB-0152-CN
Recombinant Human Anti-TREM2 Antibody
(Pil.02.002)
Pil.02.002 Human Human, Mouse ELISA, FC
TREM2 HPAB-0153-CN
Recombinant Human Anti-TREM2 Antibody
(Pil.02.005)
Pil.02.005 Human Human, Mouse ELISA, FC
TREM2 HPAB-0155-CN
Recombinant Mouse Anti-TREM2 Antibody
(7E5)
7E5 Mouse
Human, other
Mammalian
WB, ELISA, FC, IHC, IF,
IP
TREM2 HPAB-0156-CN
Recombinant Mouse Anti-TREM2 Antibody
(10C1)
10C1 Mouse
Human, other
Mammalian
WB, ELISA, FC, IHC, IF,
IP
TREM2 HPAB-0157-CN
Recombinant Humanized Anti-TREM2
Antibody (hu9F5)
hu9F5 Human
Human, other
Mammalian
WB, ELISA, FC, IHC, IF,
IP
TREM2 HPAB-2960LY
Recombinant Human Anti-TREM2 Antibody
(Pi1.02.007)
Pi1.02.007 Human Human, Mouse ELISA, FC
TREM2 HPAB-3341LY
Recombinant Humanized Anti-TREM2
Antibody (4D11)
4D11 Humanized Human FC, WB, IP, ELISA, IHC
TREM2 HPAB-3342LY
Recombinant Humanized Anti-TREM2
Antibody (78C5)
78C5 Humanized Human FC, WB, IP, ELISA, IHC
TREM2 HPAB-3343LY
Recombinant Humanized Anti-TREM2
Antibody (6G12)
6G12 Humanized Human FC, WB, IP, ELISA, IHC
TREM2 HPAB-3344LY
Recombinant Humanized Anti-TREM2
Antibody (8F11)
8F11 Humanized Human FC, WB, IP, ELISA, IHC
TREM2 HPAB-3345LY
Recombinant Humanized Anti-TREM2
Antibody (8E10)
8E10 Humanized Human FC, WB, IP, ELISA, IHC
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22. TREM2 Antibodies
Target Cat Product Name Clone Host Species Reactivity Application
TREM2 HPAB-3374LY
Recombinant Humanized Anti-TREM2 Antibody
(40D5)
40D5 Humanized Human
FC, WB, IP, ELISA,
IHC
TREM2 HPAB-3375LY
Recombinant Humanized Anti-TREM2 Antibody
(43B9)
43B9 Humanized Human
FC, WB, IP, ELISA,
IHC
TREM2 HPAB-3376LY
Recombinant Humanized Anti-TREM2 Antibody
(44A8V1)
44A8V1 Humanized Human
FC, WB, IP, ELISA,
IHC
TREM2 HPAB-3377LY
Recombinant Humanized Anti-TREM2 Antibody
(44A8V2)
44A8V2 Humanized Human
FC, WB, IP, ELISA,
IHC
TREM2 HPAB-3378LY
Recombinant Humanized Anti-TREM2 Antibody
(44B4V1)
44B4V1 Humanized Human
FC, WB, IP, ELISA,
IHC
TREM2 HPAB-3379LY
Recombinant Humanized Anti-TREM2 Antibody
(44B4V2)
44B4V2 Humanized Human
FC, WB, IP, ELISA,
IHC
TREM2 HPAB-3380LY
Recombinant Humanized Anti-TREM2 Antibody
(29F7)
29F7 Humanized Human
FC, WB, IP, ELISA,
IHC
TREM2 HPAB-3381LY
Recombinant Humanized Anti-TREM2 Antibody
(32G1)
32G1 Humanized Human
FC, WB, IP, ELISA,
IHC
TREM2 HPAB-N0292-YC Recombinant Rat Anti-TREM2 Antibody (14D3) 14D3 Rat Human ELISA, Inhib
TREM2 TAB-168CQ Anti-Human TREM2 Antibody (Ab21) Ab21 Human Human, Mouse
ELISA, FC, WB,
FuncS
TREM2 TAB-169CQ Anti-Human TREM2 Antibody (Ab52) Ab52 Human Human, Mouse
ELISA, FC, WB,
FuncS
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23. CCR5 Antibodies
Target Cat Product Name Clone Host Species Reactivity Application
CCR5 HPAB-0047-YC
Recombinant Humanized Anti-CCR5 Antibody
(huPR0140)
huPR0140 Human Human Block
CCR5 HPAB-0131CQ
Recombinant Human Anti-CCR5 Antibody
(Pz02.1C11)
Pz02.1C11 Human Human ELISA, FC
CCR5 HPAB-1038-FY Recombinant Anti-CCR5 Antibody (36F11) 36F11 Human Human ELISA, FC
CCR5 HPAB-1659-FY
Recombinant Human Anti-CCR5 Antibody
(XF27/28.36F11)
XF27/28.36F11 Human Human ELISA
CCR5 HPAB-1660-FY
Recombinant Mouse Anti-CCR5 Antibody
(Pz01.F3)
Pz01.F3 Mouse Human ELISA
CCR5 HPAB-1662-FY
Recombinant Mouse Anti-CCR5 Antibody
(PzO3.1C5)
PzO3.1C5 Mouse Human ELISA
CCR5 MOB-0372CT
Recombinant Mouse anti-Human CCR5
Monoclonal antibody (56634.222)
56634.222 Mouse Human FC, ICC
CCR5 MOR-0522
Hi-Affi™ Recombinant Rabbit Anti-CCR5
Monoclonal Antibody (DS522AB)
DS522AB Rabbit Human WB, FC
CCR5 NEUT-268CQ
Recombinant Mouse Anti-CCR5 Antibody
(CBL472)
CBL472 Mouse Human FC, CyTOF, ICC, Neut
CCR5 NS-017CN
Recombinant Mouse Anti-CCR5 Antibody
(PA14)
PA14 Mouse Human ELISA, WB, FC
CCR5 PABC-446
Recombinant Mouse Anti-CCR5 Antibody
(4B08)
4B08 Mouse Human ELISA
CCR5 PABL-345
Recombinant Mouse Anti-The extracellular
domain of CCR5 Antibody (RoAb13)
RoAb13 Mouse Human BL, ELISA, FACS
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24. CGRP Antibodies
Target Cat Product Name Clone Host Species Reactivity Application
CGRP HPAB-0099CQ Recombinant Human Anti-CGRP Antibody (G1) G1 Human Human, Rat ELISA, BL
CGRP HPAB-1075-FY Recombinant Anti-CGRP Antibody (G2) G2 Mouse Human, Rat ELISA
CGRP HPAB-2072LY
Recombinant Mouse Anti-CGRP Antibody
(CBL077)
CBL077 Mouse Human ELISA
CGRP HPAB-3104LY
Recombinant Humanized Anti-CGRP Antibody
(Ab1)
Ab1 Humanized Human ELISA
CGRP HPAB-3113LY
Recombinant Humanized Anti-CGRP Antibody
(Ab12)
Ab12 Humanized Human ELISA
CGRP HPAB-3114LY
Recombinant Humanized Anti-CGRP Antibody
(Ab13)
Ab13 Humanized Human ELISA
CGRP HPAB-3115LY
Recombinant Humanized Anti-CGRP Antibody
(Ab14)
Ab14 Humanized Human ELISA
CGRP TAB-163CL Anti-Human CGRP Antibody (ALD403) ALD403 Humanized Human ELISA
CGRP TAB-425CQ Anti-Human CGRP Antibody (Eptinezumab) Eptinezumab Human Human
ELISA, IHC, FC, IP,
IF, Inhib
CGRP TAB-428CQ Anti-Human CGRP Antibody (Fremanezumab) Fremanezumab Human Human
ELISA, IHC, FC, IP,
IF, Inhib
CGRP TAB-429CQ Anti-Human CGRP Antibody (Galcanezumab) Galcanezumab Human Human
ELISA, IHC, FC, IP,
IF, Inhib
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25. PSEN1/BPTF/CTNNB1/BCHE Antibodies
Target Cat Product Name Clone Host Species Reactivity Application
PSEN1 BRD-1139MZ Chicken Anti-Presenilin 1 Polyclonal IgY Chicken Human WB, ELISA
PSEN1 MOB-1686CT
Recombinant Mouse anti-Human PSEN1
Monoclonal antibody (45-5D4)
45-5D4 Mouse Human IP, WB
PSEN1 MOR-2883
Hi-Affi™ Recombinant Rabbit Anti-PSEN1
Monoclonal Antibody (DS2883AB)
DS2883AB Rabbit Human WB, IP, ICC, FC, IHC-P
PSEN1 TAB-714CL Anti-Human PSEN1 Therapeutical Antibody Rabbit Human ELISA
BPTF DrMAB-239
Recombinant Human Anti-Human BPTF Antibody,
clone D378
D378 Human Human ELISA, IP-MS
BPTF MOB-1471MZ
Recombinant Mouse Anti-Human BPTF Antibody
(clone 3454D4b)
3454D4b Mouse Human WB
CTNNB1 NS-008CN Recombinant Mouse Anti-CTNNB1 Antibody (13C6) 13C6 Mouse Human ELISA, IHC
CTNNB1 PABZ-140
Recombinant Mouse Anti-Rabbit CTNNB1 (residue
19-44) Antibody (BC-22)
BC-22 Mouse Rabbit ELISA, BL
BCHE FAMAB-0031CQ Recombinant Mouse Anti-BCHE Antibody (mAb2) mAb2 Mouse
Human, Rhesus
monkey, Horse, Cat,
Tiger, Pig, Bovine
ELISA
BCHE FAMAB-0028CQ Recombinant Mouse Anti-BCHE Antibody (11D8) 11D8 Mouse Human ELISA, WB
BCHE FAMAB-0029CQ Recombinant Mouse Anti-BCHE Antibody (B2 12-1) B2 12-1 Mouse Human ELISA
BCHE FAMAB-0030CQ Recombinant Mouse Anti-BCHE Antibody (B2 18-5) B2 18-5 Mouse
Human, Rhesus
monkey, Horse, Cat,
Tiger
ELISA
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26. ANTIBODIES
FOR
ALZHEIMER’S
DISEASE
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