This document discusses acute abdomen, defined as sudden abdominal pain that requires urgent treatment. It lists over 1000 potential causes organized by system, pathology, and area affected. Common causes include appendicitis, cholecystitis, diverticulitis, pancreatitis, bowel obstructions, ectopic pregnancy, and renal colic. A thorough history and physical exam are important for diagnosis, with symptoms varying depending on the specific condition. Factors like onset, location, radiation, aggravating/relieving factors, and associated symptoms provide clues to the underlying etiology.
2. "An acute abdomen" denotes any
sudden, spontaneous, nontraumatic
disorder whose chief manifestation is
in the abdominal area and for which
urgent operation may be necessary.
Because there is frequently a
progressive underlying intra-
abdominal disorder, undue delay in
diagnosis and treatment adversely
affects outcome
DefinitionDefinition
3. condition characterized by severe
abdominal pain which develops
over a period of 8 hrs. In pt who
have been previously well.
rapid and accurate diagnosis is
essential for morbidity and mortality
process.
11. Structures Nervous System
Pathways
Sensory Level
Liver, spleen,
and central
part of
diaphragm
Phrenic nerve C3–5
Peripheral
diaphragm,
stomach,
pancreas,
gallbladder,
and small
bowel
Celiac plexus
and greater
splanchnic
nerve
T6–9
Appendix,
colon, and
pelvic viscera
Mesenteric
plexus and
lesser
splanchnic
nerve
T10–11
14. MedicalMedical gynecologicalgynecological
Myocardial InfarctionMyocardial Infarction
GastritisGastritis
GastroenteritisGastroenteritis
HepatitisHepatitis
Urinary Tract InfectionUrinary Tract Infection
Ectopic pregnancyEctopic pregnancy
Ovarian cyst torsionOvarian cyst torsion
EndometriosisEndometriosis (endometrial(endometrial
cells are deposited in areas outside thecells are deposited in areas outside the
uterine cavity )uterine cavity )
15. Endocrine and Metabolic Causes
Uremia
Diabetic crisis
Addisonian crisis
Acute intermittent porphyria
Hereditary Mediterranean fever
Hematologic Causes
Sickle cell crisis
Acute leukemia
Other blood dyscrasias
Toxins and Drugs
Lead poisoning
Other heavy metal poisoning
Narcotic withdrawal
Black widow spider poisoning
Nonsurgical Causes of Acute Abdomen
16. WWW.SMSO.CCWWW.SMSO.CC
Visceral painVisceral pain
– Distention, inflammation or ischaemiaDistention, inflammation or ischaemia
in hollow viscous & solid organsin hollow viscous & solid organs
– Localisation depends on theLocalisation depends on the
embryologic origin of the organ:embryologic origin of the organ:
Forgut to epigastriumForgut to epigastrium
Midgut to umbilicusMidgut to umbilicus
Hindgut to the hypogastric regionHindgut to the hypogastric region
Parietal painParietal pain
– is localised to the dermatome aboveis localised to the dermatome above
the site of the stimulus.the site of the stimulus.
Referred painReferred pain
– produces symptoms, not signs e.g.produces symptoms, not signs e.g.
tendernesstenderness
18. Abdominal Pain
visceral pain :is elicited by distention, by
inflammation or ischemia stimulating the
receptor neurons, or by direct involvement (e.g.,
malignant infiltration) of sensory nerves. The
centrally perceived sensation is generally slow in
onset, dull, poorly localized, and protracted
parietal pain : is mediated by both C and A
delta nerve fibers, the latter being responsible
for the transmission of more acute, sharper,
better-localized pain sensation. Direct irritation
of the somatically innervated parietal peritoneum
(especially the anterior and upper parts) by pus,
bile, urine, or gastrointestinal secretions leads to
19. Ref erred
Produces sympt oms not si gns
Based on devel opment al embryol ogy
- Uret eral obst ruct i on →
t est i cul ar pai n
- Subdi aphragmat i c i rri t at i on →
i psi l at eral shoul der or
supracl avi cul ar pai n
- Gynecol ogi c pat hol ogy back→
or proxi mal l ower ext remi t y
- Bi l i ary di sease ri ght→
i nf rascapul ar pai n
- MI epi gast ri c, neck, j aw or→
upper ext remi t y pai n
29. Acute cholecytitis
Constant moderate pain in RUQ
radiated to Rt shoulder tip +
nausea, bilious vomitus, low grade
fever & jaundice
30. Perforated peptic ulcer,
Sudden onset of pain in
midepigastrium that spreads and is
aggravated by movement; patient
appears acutely ill and is reluctant
to move; rigid abdomen; grunting
respiration; bowel sounds absent
31. Ectopic pregnancy,
Pain sudden, severe,persistent,following
a missed or abnormal period, typically
epigastric; associated with hypotension
and tachycardia
Ovarian cyst
Pain constant with sharp, sudden onset,
usually in ipsilateral hypogastrium; may
have nausea and vomiting following the
pain.
32. Pelvic inflammatory disease.
Pain at end of or after normal
menstrual period, bilateral lower
quadrant pain aggravated by
cervical manipulation; anorexia,
nausea, and vomiting rare; possible
cervical discharge; fever
33. Urinary stone,
Pain location changes with
movement of stone, may radiate to
testicle, groin of involved side, pain
very severe; patient cannot get
comfortable
34. Clinical evaluationClinical evaluation
HistoryHistory
AgeAge
Certain conditions occur in certain age groupsCertain conditions occur in certain age groups
E.g.E.g. diverticulitis in elderlydiverticulitis in elderly
Mesenteric adenitisMesenteric adenitis (inflammation of mesenteric lymph(inflammation of mesenteric lymph
nodes)nodes) in childrenin children
PainPain
– OnsetOnset
sudden perforationsudden perforation
gradual inflammatory causesgradual inflammatory causes
36. History, cont…History, cont…
– NatureNature
colicky obstruction (cramping pain)colicky obstruction (cramping pain)
dull inflammation e.g. pancreatitisdull inflammation e.g. pancreatitis
(constant pain)(constant pain)
– RadiationRadiation
to tip of the right shoulder in acuteto tip of the right shoulder in acute
cholecystitis (boa’s sign)cholecystitis (boa’s sign)
40. ExaminationExamination
Note: physical signs may be less obviousNote: physical signs may be less obvious
in elderly, obese patients, and those onin elderly, obese patients, and those on
steroidssteroids
General examinationGeneral examination
– Motionless peritonitisMotionless peritonitis
– in agony colicin agony colic
– Jaundice- obstructive jaundiceJaundice- obstructive jaundice
– dehydrationdehydration
41. Examination, cont…Examination, cont…
Vital signsVital signs
– PulsePulse
– Respiratory rateRespiratory rate
– Blood PressureBlood Pressure
High grade feverHigh grade fever Low grade feverLow grade fever
Acute cholangitisAcute cholangitis
(Fever,jaundice,abdominal pain due to(Fever,jaundice,abdominal pain due to
bacterial proliferation superimposed onbacterial proliferation superimposed on
obstruction of biliary tree due to gallobstruction of biliary tree due to gall
stones)stones)
PeritonitisPeritonitis
Acute cholecystitisAcute cholecystitis
AppendicitisAppendicitis
42. Abdominal examinationAbdominal examination
InspectionInspection
What you seeWhat you see What it meansWhat it means
DistensionDistension
RigidityRigidity
Decreased movementDecreased movement
ScarsScars
HerniaHernia
Visible peristalsisVisible peristalsis
Intestinal Obstruction , AscitisIntestinal Obstruction , Ascitis
PeritonitisPeritonitis
PeritonitisPeritonitis
AdhesionsAdhesions
Intestinal ObstructionIntestinal Obstruction
Intestinal ObstructionIntestinal Obstruction
43. Abdominal examination,Abdominal examination,
cont…cont… Palpation-(to feel)Palpation-(to feel)
signsign significancesignificance
Tenderness,Tenderness,
guarding,guarding,
Rebound tendernessRebound tenderness
Rigidity (board like)Rigidity (board like)
Pulsatile massPulsatile mass
Succession splashSuccession splash
(splashing sound due to presence(splashing sound due to presence
Inflammation of parietalInflammation of parietal
peritoniumperitonium
peritonitisperitonitis
Aortic aneurysmAortic aneurysm
Gastric outlet obstructionGastric outlet obstruction
44. Abdominal examination,Abdominal examination,
cont…cont…
PercussionPercussion-(tapping on a surface)-(tapping on a surface)
signsign significancesignificance
ResonanceResonance
Loss of liver dullnessLoss of liver dullness
Shifting dullnessShifting dullness
Intestinal ObstructionIntestinal Obstruction
PerforationPerforation
Ascitis, free fluidAscitis, free fluid
45. Abdominal examination,Abdominal examination,
cont…cont…
AuscultationAuscultation
signsign significancesignificance
Absent bowel soundsAbsent bowel sounds
Increased sound,Increased sound,
BorborygmiBorborygmi (rumbling(rumbling
sound caused by gas moving)sound caused by gas moving)
BruitBruit (Abnormal sound over(Abnormal sound over
blood vessel)blood vessel)
Paralytic ileusParalytic ileus etcetc
Mechanical obstructionMechanical obstruction
Vascular diseaseVascular disease
51. Aaron sign
– Pain or pressure in epigastrium or anterior chest with persistent
firm pressure applied to McBurney's point for Acute appendicitis
Bassler sign
– Sharp pain created by compressing appendix between abdominal
wall and iliacus for Chronic appendicitis
Blumberg's sign
– Transient abdominal wall rebound tenderness Peritoneal
inflammation
Carnett's sign
– Loss of abdominal tenderness when abdominal wall muscles are
contracted Intra-abdominal source of abdominal pain
Chandelier sign
– Extreme lower abdominal and pelvic pain with movement of cervix
Pelvic inflammatory disease
Charcot's sign
– Intermittent right upper abdominal pain, jaundice, and fever
Choledocholithiasis
52. Claybrook sign
– Accentuation of breath and cardiac sounds through abdominal
wall Ruptured abdominal viscus
Courvoisier's
– sign Palpable gallbladder in presence of painless jaundice
Periampullary tumor
Cruveilhier sign
– Varicose veins at umbilicus (caput medusae) Portal hypertension
Cullen's sign
– Periumbilical bruising Hemoperitoneum
Danforth sign
– Shoulder pain on inspiration Hemoperitoneum
Fothergill's sign
– Abdominal wall mass that does not cross midline and remains
palpable when rectus contracted Rectus muscle hematomas
Grey Turner's sign
– Local areas of discoloration around umbilicus and flanks Acute
hemorrhagic pancreatitis
53. Iliopsoas sign Elevation and extension of leg against resistance
creates pain = Appendicitis with retrocecal abscess
Kehr's sign Left shoulder pain when supine and pressure placed
on left upper abdomen Hemoperitoneum (especially from splenic
origin)
Mannkopf's sign Increased pulse when painful abdomen palpated
Absent if malingering
Murphy's sign Pain caused by inspiration while applying pressure
to right upper abdomen Acute cholecystitis
Obturator sign Flexion and external rotation of right thigh while
supine creates hypogastric pain Pelvic abscess or inflammatory
mass in pelvis
Ransohoff sign Yellow discoloration of umbilical region Ruptured
common bile duct
Rovsing's sign Pain at McBurney's point when compressing the
left lower abdomen Acute appendicitis
Ten Horn sign Pain caused by gentle traction of right
testicle Acute appendicitis
54. InvestigationsInvestigations
To assess patients condition in generalTo assess patients condition in general
1.1. Complete Blood Count (Blood Routine)Complete Blood Count (Blood Routine)
2.2. Electrolytes-Na ,K ,ClElectrolytes-Na ,K ,Cl
3.3. Blood Urea Nitrogen (BUN) & CreatinineBlood Urea Nitrogen (BUN) & Creatinine
4.4. Arterial Blood Gas (ABG)Arterial Blood Gas (ABG)
5.5. UrinalysisUrinalysis
6.6. Liver Function Test (LFT)Liver Function Test (LFT)
7.7. Prothrombin Time (PT)11 to 13.5 sec,PTT –25Prothrombin Time (PT)11 to 13.5 sec,PTT –25
to 35 secto 35 sec(Partial thromboplastin time)(blood test that tells how long it(Partial thromboplastin time)(blood test that tells how long it
takes for plasma to clot?)takes for plasma to clot?)
8.8. Blood grouping and cross matchingBlood grouping and cross matching
55. Investigations, cont…Investigations, cont…
2.2. Serum Beta HCGSerum Beta HCG (human chorionic(human chorionic
gonadotrophin hormone)gonadotrophin hormone)
– In female of child bearing ageIn female of child bearing age
– To rule out ectopic pregnancyTo rule out ectopic pregnancy
56. Investigations, cont…Investigations, cont…
Specific investigationsSpecific investigations
A. LabA. Lab
1.1. Amylase & lipaseAmylase & lipase
– Lipase elevation is specific for pancreatitisLipase elevation is specific for pancreatitis
– Amylase elevation confirms the diagnosisAmylase elevation confirms the diagnosis
of Pancreatitis, but also seen in:of Pancreatitis, but also seen in:
Perforated viscus (Internal organs)Perforated viscus (Internal organs)
Intestinal.ObstructionIntestinal.Obstruction
Acute cholecystitisAcute cholecystitis
57. Investigations, cont…Investigations, cont…
B. RadiologicalB. Radiological
1.1. Chest x-rayChest x-ray
Air under theAir under the
diaphragm indiaphragm in
perforated viscusperforated viscus
(duodenal perforation)(duodenal perforation)
Elevated diaphragm inElevated diaphragm in
abdominal distentionabdominal distention
58. Investigations, cont…Investigations, cont…
2.2. Abdominal x-rayAbdominal x-ray
air fluid levels in intestinal obstructionair fluid levels in intestinal obstruction
Stones (90% of kidney stones can be seenStones (90% of kidney stones can be seen
in x-ray and 10% can’t be seen but 10% ofin x-ray and 10% can’t be seen but 10% of
gallstones can be seen in x-ray but 90%gallstones can be seen in x-ray but 90%
can’t be seen) why ? Calcium .can’t be seen) why ? Calcium .
65. Investigations, cont…Investigations, cont…
5.5. Duplex scan or angiographyDuplex scan or angiography
for superior mesenteric embolus orfor superior mesenteric embolus or
thrombosisthrombosis
6.6. ERCP (Endoscopic retrogradeERCP (Endoscopic retrograde
cholangio-pancreatography)cholangio-pancreatography)
66. Investigations, cont…Investigations, cont…
C. ParacentesisC. Paracentesis
– To assess Small Bowel Perforation inTo assess Small Bowel Perforation in
ascitisascitis
– Free blood, bile, bowel contents suggestFree blood, bile, bowel contents suggest
Bowel perforationBowel perforation
D. Endoscopy & laparoscopyD. Endoscopy & laparoscopy
E. Diagnostic peritoneal lavageE. Diagnostic peritoneal lavage
70. Management, cont…Management, cont…
– AntibioticsAntibiotics
BroadspectrumBroadspectrum
In case of sepsis or peritonititsIn case of sepsis or peritonitits
71. Management, cont…Management, cont…
Surgical managementSurgical management
– IndicationsIndications
1.1. Physical findingsPhysical findings
Localized peritoneal irritation with guardingLocalized peritoneal irritation with guarding
or rigidityor rigidity
Spreading tendernessSpreading tenderness
Tense or progressive distensionTense or progressive distension
Tender abdominal or rectal mass with highTender abdominal or rectal mass with high
fever or hypotensionfever or hypotension
72. Indications for surgery,Indications for surgery,
cont…cont…
Rectal bleeding with shock or acidosisRectal bleeding with shock or acidosis
Equivocal (uncertain)abdominal findings withEquivocal (uncertain)abdominal findings with
– Septicemia: high fever, leukocytosis,Septicemia: high fever, leukocytosis,
mental status changesmental status changes
– Bleeding: shock, acidosis, fallingBleeding: shock, acidosis, falling
hematocrithematocrit
– Suspected ischemia: acidosis, fever,Suspected ischemia: acidosis, fever,
tachycardiatachycardia
73. Indications for surgery,Indications for surgery,
cont…cont…
2.2. Radiological findingsRadiological findings
Pneumoperitonium –bowel perforationPneumoperitonium –bowel perforation
Gross or progressive bowel distension-bowelGross or progressive bowel distension-bowel
obstructionobstruction
Free extravasation of contrast media-bowelFree extravasation of contrast media-bowel
perforationperforation
Space occupying lesion –Mass or tumorSpace occupying lesion –Mass or tumor
Mesenteric occlusion-IschemiaMesenteric occlusion-Ischemia
76. The Acute Abdomen: Management OptionsThe Acute Abdomen: Management Options
Emergent (‘surgery now’)Emergent (‘surgery now’)
Urgent (‘surgery today’)Urgent (‘surgery today’)
Semi-urgent (‘surgery tomorrow’)Semi-urgent (‘surgery tomorrow’)
Non operativeNon operative
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- Act i ve observat i on
- Di scharge
77. Abdominal Pain ClinicalAbdominal Pain Clinical
PearlsPearls Significant abdominal tenderness should never be attributed toSignificant abdominal tenderness should never be attributed to
gastroenteritisgastroenteritis
Incidence of gastroenteritis in the elderly is very lowIncidence of gastroenteritis in the elderly is very low
Always perform genital examinations when lower abdominal painAlways perform genital examinations when lower abdominal pain
is present – in malesis present – in males andand females, infemales, in youngyoung andand oldold
In older patients with renal colic symptoms, exclude AAAIn older patients with renal colic symptoms, exclude AAA
Severe pain should be taken as an indicator of serious diseaseSevere pain should be taken as an indicator of serious disease
Pain awakening the patient from sleep should always bePain awakening the patient from sleep should always be
considered signficantconsidered signficant
Sudden, severe pain suggests serious diseaseSudden, severe pain suggests serious disease
Pain almost always precedes vomiting in surgical causes;Pain almost always precedes vomiting in surgical causes;
converse is true for most gastroenteritis and NSAPconverse is true for most gastroenteritis and NSAP
Acute cholecystitis is the most common surgical emergency inAcute cholecystitis is the most common surgical emergency in
the elderlythe elderly
A lack of free air on a chest xray does NOT rule out perforationA lack of free air on a chest xray does NOT rule out perforation
Signs and symptoms of PUD, gastritis, reflux and nonspecificSigns and symptoms of PUD, gastritis, reflux and nonspecific
dyspepsia have significant overlapdyspepsia have significant overlap
If the pain of biliary colic lasts more than 6 hours, suspect earlyIf the pain of biliary colic lasts more than 6 hours, suspect early
cholecystitischolecystitis
Editor's Notes
For free air – instill 500cc of air into stomach via NGT and repeat xray or do noncontrast CT scan