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DR. ARCHANA DHAVALSHANKH
PROF & HEAD, DEPT. OF PHARMACOLOGY
D Y PATIL MEDICAL COLLEGE, KOLHAPUR
Comp 1.1
SYLLABUS FOR PHARMACOLOGY
Sr. No. Topics
1 General Pharmacology
2 Drugs acting on A.N.S (Autonomic Nervous System)
3 Drugs acting on C.V.S (Cardiovascular System)
4 Drugs acting on C.N.S (Central Nervous System)
5 Blood (Hematinic) , Diuretics
6 Drugs acting on R.S (Respiratory System)
7 Drugs acting on G.I. Tract
8 Drugs acting on Endocrine system
9 Drugs in Chemotherapy
10 Vitamins , Vaccines,
11 Autocoids
12 Pandemic Module
13 AETCOM
TEXT- BOOKS FOR PHARMACOLOGY
Sr.
No.
Text Book Author Edition
1 The
Pharmacological
Basis of
Therapeutics
Goodman Gillman 13 th Edition
2 Basic and
Clinical
Pharmacology
Bertram G Katzung 14 th Edition
3 Essentials of
Medical
Pharmacology
K. D. Tripathi 8 th edition
4 Pharmacology
and Pharmaco-
therapeutics
Satoskar and
Bhandarkar
26 th edition
5 Principles of
Pharmacology
KK Sharma 3 rd edition
OBJECTIVES
 Need to learn Pharmacology
 Definition & Terminology
 Braches of Pharmacology
 Sources of Drug
 Sources of Drug Information
WHY DO WE NEED TO STUDY PHARMACOLOGY?
Therapeutic methods- Ways to treat diseases
Most diseases requires a combination of therapeutic methods
for successful treatment.
1. Drug therapy – Txt with drugs
2. Diet therapy – Tx by diet – Low salt diet for cardio diseases
3. Physiotherapy – Tx with natural physical forces (water, light
& heat)
4. Psychological therapy – Identification of stressors and
methods to reduce or eliminate stress/use of drugs
DEFINITIONS
1. Pharmacology = The study or science of drugs.
Pharma = Drugs Logos = Knowledge
- derived from two Greek words:
Pharmakon (Greek word for drugs) and logos (the Greek word for
science) (a discourse or treatise)
It includes physical and chemical properties, biochemical and
physiological effects, mechanism of action, therapeutic uses and
adverse effects of drugs.
2. DRUG • French: Drogue – a dry herb
A single active chemical entity present in a medicine that is used for diagnosis,
prevention and treatment of diseases Broadly defined as how chemical agents
affect living processes:
- Hormones
- Neurotransmitters
- Growth factors
- Drugs (pharmaceuticals)
- Toxic agents in the environment
- NCE - The medicinal/organic chemists may create the candidate compound
(sometimes referred to as a new chemical entity, (NCE).
It is the pharmacologist who is responsible for testing it for pharmacological
activity.
Ultimately will lead to the discovery of novel drugs for therapeutic intervention.
WHO – in 1966 – “ Drug is any substance or product which is
used or intended to be used
to modify or explore physiological systems or pathological states
for the benefit of the recipient.”
Pharmacologist – is a scientist who
specializes in the study of pharmacodynamics
employing all kinds of biochemical, physiological
and other techniques.
Pharmacy- is a medical science concerned
with the safe & effective use of medicines
- The study of techniques involved in the
preparation, compounding, preservation & storage
of the drugs for medical use
Clinical Pharmacology – Study of
drugs in humans (patients or volunteers )
• Deals with ADME process.
• i.e. what the body drug does with the drug.
Pharmaco
Kinetics
• Deals with biological effects of drug, its mechanism of action of drug ,
relationship b/w plasma concentration & its response, duration of action,
• i.e. what the drug does with the body
Pharmaco
Dynamics
• Clinical applications of pharmacokinetics &
pharmacodynamic information to cure the disease.
Pharmaco
Therapeutics
• Deals with the comparative clinical evaluation of
new drug for its therapeutic efficacy & safety
Clinical
Pharmacology
• Deals with the toxicity & poisonous effects of the drugs
• Also with symptoms & treatment of poisoning.
Toxicology
Pharmacology -Subdivisions
Involves the study of Absorption,
Distribution,
Metabolism
(Biotransformation)
Excretion
Absorption
Distribution
Metabolism
Biotransformation
Excretion
Elimination
Site of action
Mechanism of action
Effects of drugs
Side/Adverse effects of drugs
Drug / Food interactions
Dose response / Efficacy/
potency
Pharmacotherapeutics
Pharmacogenetics
Toxicology
Sources of Drug
Plant Source Drug Use
Chinchona Bark Quinidine Malaria
Antiarrhythmic
Purple Foxglove Leaf Digitalis Cardiotonic
CHF
Poppy Plant
Opium
Fruit Morphine
Codeine
Analgesic
Antitussive
Antidiarrheal
Eserine Seed Anticholinesterase Myasthenia Gravis
Nicotinia Tabacum Flower Nicotine Ganglion blocker
Atropa Belladonna Anticholinergics OP Poisoning
Vinca Rosea Fruits Vinca alkaloids Anti cancer
Rauwolfia
Serpentina
Flower Risperidone Antihypertensive
Nature of Drug
1. Sources of drug
2. Nature of drug derived from plant
3. Sources of drug information
4. Drug categories
5. Definition:
Pharmacodynamics
Pharmacokinetics
Drug
Pharmacology
Pharmacotherapeutics
Pharmacogenetics
Clinical Pharmacology
ASSIGNMENT- 1
Name
Roll No
Subject
Index
Topic
Name of
Teacher
Assignment

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Introduction to pharmacology

  • 1. DR. ARCHANA DHAVALSHANKH PROF & HEAD, DEPT. OF PHARMACOLOGY D Y PATIL MEDICAL COLLEGE, KOLHAPUR Comp 1.1
  • 2. SYLLABUS FOR PHARMACOLOGY Sr. No. Topics 1 General Pharmacology 2 Drugs acting on A.N.S (Autonomic Nervous System) 3 Drugs acting on C.V.S (Cardiovascular System) 4 Drugs acting on C.N.S (Central Nervous System) 5 Blood (Hematinic) , Diuretics 6 Drugs acting on R.S (Respiratory System) 7 Drugs acting on G.I. Tract 8 Drugs acting on Endocrine system 9 Drugs in Chemotherapy 10 Vitamins , Vaccines, 11 Autocoids 12 Pandemic Module 13 AETCOM
  • 3. TEXT- BOOKS FOR PHARMACOLOGY Sr. No. Text Book Author Edition 1 The Pharmacological Basis of Therapeutics Goodman Gillman 13 th Edition 2 Basic and Clinical Pharmacology Bertram G Katzung 14 th Edition 3 Essentials of Medical Pharmacology K. D. Tripathi 8 th edition 4 Pharmacology and Pharmaco- therapeutics Satoskar and Bhandarkar 26 th edition 5 Principles of Pharmacology KK Sharma 3 rd edition
  • 4. OBJECTIVES  Need to learn Pharmacology  Definition & Terminology  Braches of Pharmacology  Sources of Drug  Sources of Drug Information
  • 5. WHY DO WE NEED TO STUDY PHARMACOLOGY? Therapeutic methods- Ways to treat diseases Most diseases requires a combination of therapeutic methods for successful treatment. 1. Drug therapy – Txt with drugs 2. Diet therapy – Tx by diet – Low salt diet for cardio diseases 3. Physiotherapy – Tx with natural physical forces (water, light & heat) 4. Psychological therapy – Identification of stressors and methods to reduce or eliminate stress/use of drugs
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  • 7. DEFINITIONS 1. Pharmacology = The study or science of drugs. Pharma = Drugs Logos = Knowledge - derived from two Greek words: Pharmakon (Greek word for drugs) and logos (the Greek word for science) (a discourse or treatise) It includes physical and chemical properties, biochemical and physiological effects, mechanism of action, therapeutic uses and adverse effects of drugs.
  • 8. 2. DRUG • French: Drogue – a dry herb A single active chemical entity present in a medicine that is used for diagnosis, prevention and treatment of diseases Broadly defined as how chemical agents affect living processes: - Hormones - Neurotransmitters - Growth factors - Drugs (pharmaceuticals) - Toxic agents in the environment - NCE - The medicinal/organic chemists may create the candidate compound (sometimes referred to as a new chemical entity, (NCE). It is the pharmacologist who is responsible for testing it for pharmacological activity. Ultimately will lead to the discovery of novel drugs for therapeutic intervention. WHO – in 1966 – “ Drug is any substance or product which is used or intended to be used to modify or explore physiological systems or pathological states for the benefit of the recipient.”
  • 9. Pharmacologist – is a scientist who specializes in the study of pharmacodynamics employing all kinds of biochemical, physiological and other techniques. Pharmacy- is a medical science concerned with the safe & effective use of medicines - The study of techniques involved in the preparation, compounding, preservation & storage of the drugs for medical use Clinical Pharmacology – Study of drugs in humans (patients or volunteers )
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  • 11. • Deals with ADME process. • i.e. what the body drug does with the drug. Pharmaco Kinetics • Deals with biological effects of drug, its mechanism of action of drug , relationship b/w plasma concentration & its response, duration of action, • i.e. what the drug does with the body Pharmaco Dynamics • Clinical applications of pharmacokinetics & pharmacodynamic information to cure the disease. Pharmaco Therapeutics • Deals with the comparative clinical evaluation of new drug for its therapeutic efficacy & safety Clinical Pharmacology • Deals with the toxicity & poisonous effects of the drugs • Also with symptoms & treatment of poisoning. Toxicology Pharmacology -Subdivisions
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  • 13. Involves the study of Absorption, Distribution, Metabolism (Biotransformation) Excretion
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  • 21. Site of action Mechanism of action Effects of drugs Side/Adverse effects of drugs Drug / Food interactions Dose response / Efficacy/ potency
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  • 39. Plant Source Drug Use Chinchona Bark Quinidine Malaria Antiarrhythmic Purple Foxglove Leaf Digitalis Cardiotonic CHF Poppy Plant Opium Fruit Morphine Codeine Analgesic Antitussive Antidiarrheal Eserine Seed Anticholinesterase Myasthenia Gravis Nicotinia Tabacum Flower Nicotine Ganglion blocker Atropa Belladonna Anticholinergics OP Poisoning Vinca Rosea Fruits Vinca alkaloids Anti cancer Rauwolfia Serpentina Flower Risperidone Antihypertensive
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  • 53. 1. Sources of drug 2. Nature of drug derived from plant 3. Sources of drug information 4. Drug categories 5. Definition: Pharmacodynamics Pharmacokinetics Drug Pharmacology Pharmacotherapeutics Pharmacogenetics Clinical Pharmacology ASSIGNMENT- 1 Name Roll No Subject Index Topic Name of Teacher Assignment