Huntingtons disease and other hereditary diseas.pdf

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Huntington\'s disease and other hereditary diseases impact people\'s lives, because they are transferred by defects or incorrect expressions of genetic material. The transfer of dominant and recessive genes has impacted people\'s mating decisions for millenia, which can have very strong impacts on people\'s lives. Solution Huntington\'s disease and other hereditary diseases impact people\'s lives, because they are transferred by defects or incorrect expressions of genetic material. The transfer of dominant and recessive genes has impacted people\'s mating decisions for millenia, which can have very strong impacts on people\'s lives..

Huntington's disease and other hereditary diseases impact people's lives, because
they are transferred by defects or incorrect expressions of genetic material. The transfer of
dominant and recessive genes has impacted people's mating decisions for millenia, which can
have very strong impacts on people's lives.
Solution
Huntington's disease and other hereditary diseases impact people's lives, because
they are transferred by defects or incorrect expressions of genetic material. The transfer of
dominant and recessive genes has impacted people's mating decisions for millenia, which can
have very strong impacts on people's lives.

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The main organelles in protein sorting and targeting are Rough endoplasmic reticulum. As the question is all about sorting and targeting to membrane and secretion, I will stick to only these two targeting pathways. Please note the mechansm of targeting proteins to other organelles such as mitichondria, ER, chloroplast is different. Journey of a secretory protein: The protein sorting and targeting occur in endoplasmic reticulum. Most of the secretory proteins as well as membrane proteins are translocated into ER co-translationally (Co-translational translocation). i.e, they are moved into ER while their translation is going on. this translocation process is mediated by Signal recognition particle (SRP). SRP recognizes N-terminal signal peptide on the protein that is being translated. The translation process pauses for a while when the ribosome-protein-SRP complex is being transported to SRP receptor on the ER membrane. The protein is inserted into translocon channel on ER membrane and enters ER. The signaal sequence from nascent peptide is immediately cleaved in case of secretoey proteins and type I transmembrane proteins by signal peptidase. the translation resumes directing the protein being formed into ER. Inside the ER, chaperone proteins bind the protein to guide through correct folding. Then the protein is transported by ER membrane vesicles to golgi apparatus for further processing like protein modification and glycosylation. ER--- cis-golgi---trans---golgi--- lysosomes. the proteins from lysosomes fuse with membrane and according to the signals present in nascent proteins, they either remain as transmembrane proteins or secreted out of the membrane. transmembrane G-receptors span the membrane seven times (also called serpentine receptors) donot contain signal sequence at N-terminal. The first transmembrane domain acts as the signal sequence that is recognized by SRP. Some secretory proteins as well as transmembrane proteins may undero post-translational translocation. i.e, transportation to ER after the completion of protein synthesis. the entire process is believed to be same as co-translational translocation. Solution The main organelles in protein sorting and targeting are Rough endoplasmic reticulum. As the question is all about sorting and targeting to membrane and secretion, I will stick to only these two targeting pathways. Please note the mechansm of targeting proteins to other organelles such as mitichondria, ER, chloroplast is different. Journey of a secretory protein: The protein sorting and targeting occur in endoplasmic reticulum. Most of the secretory proteins as well as membrane proteins are translocated into ER co-translationally (Co-translational translocation). i.e, they are moved into ER while their translation is going on. this translocation process is mediated by Signal recognition particle (SRP). SRP recognizes N-terminal signal peptide on the protein that is being translated. The translation process pauses for a .

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Solution : Polymerase chain reaction is process in which several copy of specific segment of DNA can be produced within short interval of time.PCR include various cycles of heating and cooling.DNA is double stranded structure.Initially,DNA molecule is heated to divide it into two single strands.Then under lower temperature condition short strand of DNA which start its synthesis are attached to DNA template.After that temperature is increased and new strand of DNA is formed..

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Pr(E) shows the probability of only event E happening. Pr(F) shows the probability of only event F happening. Pr(EUF) shows the probability of happening of either one of them, which would be, only E happening + only F happening, - both E and F happenig at the same time(which is Pr(EnF). Reason for subtractinig Pr(EnF) is, because these are common elements, and hence are already counted twice in only E happening, and only F happening, so we had to subtract it once. Thus Pr(EUF) = Pr(E) + Pr(F) - Pr(EnF) putting values, 0.7 = 0.3 + 0.6 - Pr(EnF) which gives, Pr(EnF) = 0.2 Solution Pr(E) shows the probability of only event E happening. Pr(F) shows the probability of only event F happening. Pr(EUF) shows the probability of happening of either one of them, which would be, only E happening + only F happening, - both E and F happenig at the same time(which is Pr(EnF). Reason for subtractinig Pr(EnF) is, because these are common elements, and hence are already counted twice in only E happening, and only F happening, so we had to subtract it once. Thus Pr(EUF) = Pr(E) + Pr(F) - Pr(EnF) putting values, 0.7 = 0.3 + 0.6 - Pr(EnF) which gives, Pr(EnF) = 0.2.

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NADH produced in the cytoplasm produces two to three ATP by the electron transport system FADH2 adds its electrons to the electron transport system at a lower level than NADH, so it produces approximately two ATP. Solution NADH produced in the cytoplasm produces two to three ATP by the electron transport system FADH2 adds its electrons to the electron transport system at a lower level than NADH, so it produces approximately two ATP..

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Program code examples (known also as worked examples) play a crucial role in learning how to program. Instructors use examples extensively to demonstrate the semantics of the programming language being taught and to highlight the fundamental coding patterns. Programming textbooks allocate considerable space to present and explain code examples. To make the process of studying code examples more interactive, CS education researchers developed a range of tools to engage students in the study of code examples. These tools include codecasts (codemotion,codecast,elicasts), interactive example explorers (WebEx, PCEX), and tutoring systems (DeepTutor). An important component in all types of worked examples is code explanations associated with specific code lines or code chunks of an example. The explanations connect examples with general programming knowledge explaining the role and function of code fragments or their behavior. In textbooks, these explanations are usually presented as comments in the code or as explanations on the margins. The example explorer tools allow students to examine these explanations interactively. Tutoring systems, which engage students in explaining the code, use these model explanations to check student responses and provide scaffolding. In all these cases, to make a worked example re-usable beyond its presentation in a lecture, the explanations have to be authored by instructors or domain experts i.e., produced and integrated into a specific system. As the experience of the last 10 years demonstrated, these explanations are hard to obtain. Those already collected are usually “locked” in a specific example-focused system and can’t be reused. The purpose of this working group is to support broader re-used of worked examples augmented with explanations. Our current plan is to develop а standard approach to represent explained examples. This approach will enable an example created for any of the existing systems to be explored in a standard format and imported into any other example-focused system. We plan to follow a successful experience of the PEML working group focused on re-using programming exercises.

SPLICE Working Group:Reusable Code Examples

SPLICE Working Group:Reusable Code Examples

SPLICE Working Group:Reusable Code Examples

Peter Brusilovsky

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Analyzing and resolving a communication crisis in Dhaka textiles LTD.pptx

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FICTIONAL SALESMAN/SALESMAN SNSW 2024.pdf

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