2. ā¢ Human body is made up of different organs
ā¢ Different organs are made up of tissues
ā¢ Tissues are made up of cells
ā¢ Nearly 210 different types of cells are present
in human body
4. ā¢ In an adult body most of the cells got the
ability for division
ā¢ It can form it's own types of cells
Skin cells Skin cells
Liver cells Liver cells
5. ā¢ Self renewal
ā¢ Unspecialized
ā¢ Clonality
ā¢ Can be induced to form specific cell types.
28. SCAN ā Stem Cell Action Network
Embryonic Stem Cells:
Researchers extract stem cells from a 5-7 days oldResearchers extract stem cells from a 5-7 days old blastocystblastocyst..
Stem cells can divide in culture to form more of their own kind,Stem cells can divide in culture to form more of their own kind,
thereby creating a stem cell rittyjose ne.thereby creating a stem cell rittyjose ne.
The research aims to induce these cells to generate healthy tissue needed
by patients.
29. SCAN ā Stem Cell Action Network
Tens of thousands of
frozen embryos are
routinely destroyed when
couples finish their
treatment.
These surplus
embryos can be used to
produce stem cells.
Regenerative medical
research aims to
develop these cells into
new, healthy tissue to
heal severe illnesses.
30. SCAN ā Stem Cell Action Network
The Ethical DebateIn favor of ESCR:
Embryonic stem cell research (ESCR) fulfills the ethical obligation to alleviate
human suffering.
ā¢ Since excess IVF embryos will be discarded anyway, isnāt it better that they be
used in valuable research?
ā¢ SCNT (Therapeutic Cloning) produces cells in a petri dish, not a pregnancy.
Against ESCR:
In ESCR, stem cells are taken from a human blastocyst, which is then destroyed.
This amounts to āmurder.ā
ā¢ There is a risk of commercial exploitation of the human participants in ESCR.
ā¢ Slippery slope argument: ESCR will lead to reproductive cloning.
31. SCAN ā Stem Cell Action Network
Key Ethical Issues
ā¢ The blastocyst used in stem cell research is
microscopically small and has no nervous system.
Does it count as a āpersonā who has a right to life?
ā¢ What do various religions say about when
personhood begins? Does science have a view on
this?
ā¢ In a society where citizens hold diverse religious
views, how can we democratically make humane
public policy?
32. Possible Uses of Stem Cell Technology
ā¢ Replaceable tissues/organs
ā¢ Repair of defective cell types
ā¢ Delivery of genetic therapies
ā¢ Delivery chemotherapeutic agents
33. Moral and Ethical Considerations
of Stem Cell and Cloning Research
ā¢ Adult stem cells
ā¢ Embryonic stem cells
ā Embryo must be destroyed
ā When does human life/personhood begin?
ā¢ Human cloning
ā Embryos (see above)
ā Reproductive cloning
In theory, stem cell technology could be used to produce replaceable tissues or organs. Defective tissues/organs could be repaired using healthy cells. It would also be possible to genetically engineer stem cells to accomplish activities that they would not ordinarily be programmed to do. Part of this engineering could involve the delivery of chemotherapeutic agents for treatment of cancers and tumors.
The next 22 slides will examine the morality and ethics of stem cell research and human cloning. Adult stem cells (obtained from adult tissues, cord blood, etc.) do not pose any ethical controversies, since they do not destroy complete human beings. However, embryonic stem cells are isolated by destroying human embryos - the form in which all of us began our lives. Some say these embryos are not persons. We will examine this issue in depth. In addition, we will examine human cloning, including reproductive cloning.