covers Introduction. History of probiotics. General characteristics of probiotics. Why are probiotics important to human health? Some probiotics strains. Mechanism of action Advantages of host and type of advantages. Classification of probiotics and examples. Probiotics but not antibiotics, explanation with AAD. Some probiotic food. Probiotics and cancer. Disadvantages of probiotics Status of probiotics in india India and global probiotics manufactures.

1. Probiotics :The friendly
microbial consortia
Anirban Chakrabarty
3rd yr; Microbiology(Hons)
Email:
anirbanchakrabarty1996@gmail.com

2. Presentation layout
 Introduction.
 History of probiotics.
 General characteristics of probiotics.
 Why are probiotics important to human health?
 Some probiotics strains.
 Mechanism of action
 Advantages of host and type of advantages.
 Classification of probiotics and examples.
 Probiotics but not antibiotics, explanation with AAD.
 Some probiotic food.
 Probiotics and cancer.
 Disadvantages of probiotics
 Status of probiotics in india
 India and global probiotics manufactures.

3. What are Probiotics?
“Live microorganisms which
when administered in
adequate amounts confer a
health benefit on the host "as
defined by WHO.
•WHY PROBIOTICS?
Antibiotic therapy kills both
pathogenic and beneficial
bacteria, thus affecting
digestion and growth.
 For non antibiotic disease
prevention microbiologist
turned to PROBIOTICS so
called because they complete
and throw out rather than kill
bad bacteria as antibiotic
would do.

4. • In 1907 Metchnikoff proposed that the acid producing
bacteria in fermented milk products could prevent “fouling”
in the large intestine and if consumed regularly, lead to a
longer, healthier life.

6. Characteristics of Effective Probiotics
• Able to survive the passage through the digestive system.
• Able to attach to the intestinal epithelia of the host .
• Colonization at the GI tract and shows antimicrobial property.
• Be easily cultured.
• Able to maintain good viability.
• Able to utilize the nutrients and substrates in a normal diet.
• non pathogenic and non toxic.
• Capable of exerting a beneficial effect on the host.
• Stability of desired characteristics during processing, storage and
transportation.
• Withstand with HCl in the stomach and bile salt in the intestine.
• Anti-inflammatory, antimutagenic, immunostimulatory,
anticarcinogenic activity(reduction of carcinogens) in clinical trails.

8. Probiotic strains
Lactobacillus species-
• L. acidophilus
• L. plantarum
• L. casei subspecies rhamnosus
• L. brevis
• L. delbreuckii subspecies bulgaricus
Bifidobacterium species-
• B. adolescentis
• B. bifidum
• B. longum
• B. infantis
• B. breve
Others –
 Streptococcus salivarius ssp. thermophilus
Lactococcus lactis ssp. lactis
Lactococcus lactis s ssp. cremoris
Enterococcus faecium
Leuconostoc mesenteroides ssp. dextranicum
Propionibacterium freudenreichii
Pediococcus acidilactici
Saccharomyces boulardii

9. Mechanism of action

10. Advantages and benefits of host

11. Type of advantages

12. Classification of probiotics
(wrt to their commercial application)
Feed probiotics
Water probiotics
Soil probiotics
Gut probiotics

13. Examples of the commercial feed probiotics

14. Some examples of commercial water probiotics

15. Examples of some SBOs strains

16. Some commercial gut probiotics
Name of the company
or industry
Commercial name of
the probiotics
Composition of the
probiotics
Benefits from the
probiotics
1. GROWEL
FORMULATIONS
PVT. LTD.
Hyderabad-50039
BIOLACT BIOLACT contains
starch, protein, fat
digestive enzymes a
mixture of various
probiotics ->
Lactobacillus sp.,
Saccharomyces,
Streptococcus lactis
and various vitamins
Contains high amount
of vit –c which
acts as
antioxidant,
improves
immunity .
2.SYNGERY
BIOTECHNOLOGIES
Hyderabad-500076
LACTOPLUS Lactic acid bacillus,.It
is a source of
mineral, amino acids
and vitamin like
thiamine ,riboflavin,
vit-A,B-12, vit-E.
These bacteria
displace pathogens by
competitive process
which is better than
antibiotics and these
produce bacteriocins.

17. Probiotics but not antibiotics

18. Antibiotic Associated Diarrhea
Disease Antibiotic treatment
Disturbance of
gut microbiota
Clostridium overgrowth
produces toxins
Probiotics
Diarrhea
Balance
Microbiota

19. Examples of Probiotic foods

20. Probiotics and Cancer
Probiotics
20
 Oligofructose plus two probiotic strains (L. acidophilus and
L. casei) supplementation in humans helped to decrease
levels of these gut flora enzymes.
 Probiotics reduce absorption of harmful mutagens that may
contribute to colon carcinogenesis. 20
Enzymes of Gut Flora
Glycosidase
β- glucuronidase
Azoreductase
Nitroreductase

21. Disadvantages

25. Thank you
for your attention.