4. Lap.Vs open partial nephrectomy
Item Lap. Open P value
No. of pts. 100 100
Med. Tumor
size.
2.8 cm 3.3 cm 0.005
Solitary kidney 7 28 0.001
Central tumor 35% 33% 0.83
Med.Preop.
Creatinine
1.0 mg/dL 1.0 mg/dL
5. Lap.Vs open partial nephrectomy
Item Lap. Open P value
Warm ischemia
time
28 min 18 min < 0.001
Intraop. Comp. 5% 0% 0.02
+ surgical
margin
3 0 0.11
6. Lap.Vs open partial nephrectomy
• Despite the tumor size was significantly
larger in open group, the ischemia time
was highly significant shorter in the open
group .
• The intraoperative complication was nil in
the open group.
8. functional &Oncological
outcome
• It shows significant prolonged ischemia time in lap
groups (p<0.0001)
• Significant more post operative complication .
p<0.001
• Although the operative time was less in lap groups,
but it the open group show significant difference in
the percent of high risk pts (tumor size, site, single
kidney)p<0.001
10. functional &Oncological
outcome
• Although comparable outcome ,but
ischemia time was significant longer
• An important points is the learning
curve which was too long
• In the non-experienced hands the result
will be worse in the lap groups
11. Learning curve
• The lap NSS is difficult procedure to
master and need long time learning
curve.
• It should be for exophytic non hilar
lesion.
12. Hilar tumor
Increase complication rate with up to
50% of pts have urinary leak and up to
7% of pts have positive surgical
margin.
Venkatesh et al 2005
13. Solitary kidney
In solitary kidney:
The GFR decreased by 21% and 28% in the open
and laparoscopic groups, respectively (P = 0.24).
14. Solitary kidney
• Postoperative dialysis was required acutely in
0.6% of OPNs versus 10% of LPN (P = 0.01)
• Dialysis-dependent end-stage renal failure
within 1 year occurred in 0.6% of OPN versus
6.6% of LPNs (P = 0.06).
15. LAP limitation
- LAP is contraindicated in :
I. Ischemic heart disease
II. End stage respiratory disease
III. Significant renal dysfunction
IV. Severe un corrected hypovolaemia
Burns EM et al 2010
16. LAP limitation
- LAP is contraindicated in :
I. Uncorrected coagulopathy
II. Intestinal obstruction
III. Massive haemopretoneum
IV. Peritonitis and malignant ascites.
Burns EM et al 2010
17. LAP limitation
- LAP is relatively contraindicated in :
I. pregnancy
II. Morbid obesity
III. Previous renal surgery
IV. Organomegaly
Burns EM et al 2010
18. • The 2D vision:
• The lack of depth perception is a significant sensory
loss for the surgeon.
• The learning curve is long.
• The 3D version is limited due to cost.
20. Why open? Why not lap?
• It has the best oncologic and functional
outcome.
• It is the best choice in more complex
tumor.
• The ischemia time was lower than lap.
• It overly the difficulties encountered in
any lap surgery.