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Partial nephrectomy for SRM
Open partial nephrectomy
• Open partial nephrectomy is the gold
standard approach for SRM.
functional &Oncological
outcome
• Lap.Vs open partial nephrectomy
- Gill IS,Matin,Desai, et al;J Urol. 2003
- 200 cases( 100 in each arm.)
Lap.Vs open partial nephrectomy
Item Lap. Open P value
No. of pts. 100 100
Med. Tumor
size.
2.8 cm 3.3 cm 0.005
Solitary kidney 7 28 0.001
Central tumor 35% 33% 0.83
Med.Preop.
Creatinine
1.0 mg/dL 1.0 mg/dL
Lap.Vs open partial nephrectomy
Item Lap. Open P value
Warm ischemia
time
28 min 18 min < 0.001
Intraop. Comp. 5% 0% 0.02
+ surgical
margin
3 0 0.11
Lap.Vs open partial nephrectomy
• Despite the tumor size was significantly
larger in open group, the ischemia time
was highly significant shorter in the open
group .
• The intraoperative complication was nil in
the open group.
functional &Oncological
outcome
functional &Oncological
outcome
• It shows significant prolonged ischemia time in lap
groups (p<0.0001)
• Significant more post operative complication .
p<0.001
• Although the operative time was less in lap groups,
but it the open group show significant difference in
the percent of high risk pts (tumor size, site, single
kidney)p<0.001
functional &Oncological
outcome
functional &Oncological
outcome
• Although comparable outcome ,but
ischemia time was significant longer
• An important points is the learning
curve which was too long
• In the non-experienced hands the result
will be worse in the lap groups
Learning curve
• The lap NSS is difficult procedure to
master and need long time learning
curve.
• It should be for exophytic non hilar
lesion.
Hilar tumor
 Increase complication rate with up to
50% of pts have urinary leak and up to
7% of pts have positive surgical
margin.
Venkatesh et al 2005
Solitary kidney
In solitary kidney:
The GFR decreased by 21% and 28% in the open
and laparoscopic groups, respectively (P = 0.24).
Solitary kidney
• Postoperative dialysis was required acutely in
0.6% of OPNs versus 10% of LPN (P = 0.01)
• Dialysis-dependent end-stage renal failure
within 1 year occurred in 0.6% of OPN versus
6.6% of LPNs (P = 0.06).
LAP limitation
- LAP is contraindicated in :
I. Ischemic heart disease
II. End stage respiratory disease
III. Significant renal dysfunction
IV. Severe un corrected hypovolaemia
Burns EM et al 2010
LAP limitation
- LAP is contraindicated in :
I. Uncorrected coagulopathy
II. Intestinal obstruction
III. Massive haemopretoneum
IV. Peritonitis and malignant ascites.
Burns EM et al 2010
LAP limitation
- LAP is relatively contraindicated in :
I. pregnancy
II. Morbid obesity
III. Previous renal surgery
IV. Organomegaly
Burns EM et al 2010
• The 2D vision:
• The lack of depth perception is a significant sensory
loss for the surgeon.
• The learning curve is long.
• The 3D version is limited due to cost.
port site metastasis
Why open? Why not lap?
• It has the best oncologic and functional
outcome.
• It is the best choice in more complex
tumor.
• The ischemia time was lower than lap.
• It overly the difficulties encountered in
any lap surgery.
Open nss vs lap 2

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Open nss vs lap 2

  • 2. Open partial nephrectomy • Open partial nephrectomy is the gold standard approach for SRM.
  • 3. functional &Oncological outcome • Lap.Vs open partial nephrectomy - Gill IS,Matin,Desai, et al;J Urol. 2003 - 200 cases( 100 in each arm.)
  • 4. Lap.Vs open partial nephrectomy Item Lap. Open P value No. of pts. 100 100 Med. Tumor size. 2.8 cm 3.3 cm 0.005 Solitary kidney 7 28 0.001 Central tumor 35% 33% 0.83 Med.Preop. Creatinine 1.0 mg/dL 1.0 mg/dL
  • 5. Lap.Vs open partial nephrectomy Item Lap. Open P value Warm ischemia time 28 min 18 min < 0.001 Intraop. Comp. 5% 0% 0.02 + surgical margin 3 0 0.11
  • 6. Lap.Vs open partial nephrectomy • Despite the tumor size was significantly larger in open group, the ischemia time was highly significant shorter in the open group . • The intraoperative complication was nil in the open group.
  • 8. functional &Oncological outcome • It shows significant prolonged ischemia time in lap groups (p<0.0001) • Significant more post operative complication . p<0.001 • Although the operative time was less in lap groups, but it the open group show significant difference in the percent of high risk pts (tumor size, site, single kidney)p<0.001
  • 10. functional &Oncological outcome • Although comparable outcome ,but ischemia time was significant longer • An important points is the learning curve which was too long • In the non-experienced hands the result will be worse in the lap groups
  • 11. Learning curve • The lap NSS is difficult procedure to master and need long time learning curve. • It should be for exophytic non hilar lesion.
  • 12. Hilar tumor  Increase complication rate with up to 50% of pts have urinary leak and up to 7% of pts have positive surgical margin. Venkatesh et al 2005
  • 13. Solitary kidney In solitary kidney: The GFR decreased by 21% and 28% in the open and laparoscopic groups, respectively (P = 0.24).
  • 14. Solitary kidney • Postoperative dialysis was required acutely in 0.6% of OPNs versus 10% of LPN (P = 0.01) • Dialysis-dependent end-stage renal failure within 1 year occurred in 0.6% of OPN versus 6.6% of LPNs (P = 0.06).
  • 15. LAP limitation - LAP is contraindicated in : I. Ischemic heart disease II. End stage respiratory disease III. Significant renal dysfunction IV. Severe un corrected hypovolaemia Burns EM et al 2010
  • 16. LAP limitation - LAP is contraindicated in : I. Uncorrected coagulopathy II. Intestinal obstruction III. Massive haemopretoneum IV. Peritonitis and malignant ascites. Burns EM et al 2010
  • 17. LAP limitation - LAP is relatively contraindicated in : I. pregnancy II. Morbid obesity III. Previous renal surgery IV. Organomegaly Burns EM et al 2010
  • 18. • The 2D vision: • The lack of depth perception is a significant sensory loss for the surgeon. • The learning curve is long. • The 3D version is limited due to cost.
  • 20. Why open? Why not lap? • It has the best oncologic and functional outcome. • It is the best choice in more complex tumor. • The ischemia time was lower than lap. • It overly the difficulties encountered in any lap surgery.