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I would just like a quick summary on what is going on here .pdf

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I would just like a quick summary on what is going on here. I thought it was a break in DNA caused by an RNA hybird which caused an R-loop to form, then the recruiting of BRCA1 and SETX began in order to fix the break in DNA... but i dont know whats going on here... any help would be much appericated! Genomic Stability Maintenance Transcription Regulation RNAPII.

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I would just like a quick summary on what is going on here. I thought it was a break in DNA caused by an RNA hybird which caused an R-loop to form, then the recruiting of BRCA1 and SETX began in order to fix the break in DNA... but i dont know whats going on here... any help would be much appericated! Genomic Stability Maintenance Transcription Regulation RNAPII

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