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Submitted by
VIKAS KUMAR SINGH
M. SC. (Ag),
Department of Genetics & Plant Breeding,
Chaudhary Charan Singh University,
Meerut
Submitted to
DR. S.S. Gaurav
Asso. Professor,
Department of Genetics& Plant Breeding,
Chaudhary Charan Singh University,
Meerut
GENERAL GENETICS
MUTATION IS HERITABLE CHANGES
IN THE GENETIC MATERIAL THAT
PROVIDE THE RAW MATERIAL FOR
EVOLUTION.
Classification OF MUTATION
There are different ways of classifying mutation
Functional Structural
Harmful Beneficial Neutral
Point
Frame shift
Silent
Missense
Nonsense
Beneficial Mutation
 Beneficial are the ultimate source of
genetic variation.
Raw material for evolution.
For
example,
Protection
against
HIV
infection
Neutral Mutation
A neutral mutation is a mutation that occurs in a
amino acid codon but it has no impact.
Wild-type AUG UUG CAG UGG UAA
TAC AAC GTC ACC ATT
M e t h - P h e n - G l n - T r p
TAC gAC GTC ACC ATT
AUG cUG CAG UGG UAA
Meth leu gln trp
A change in base pare results in an amino acid
change but the new amino acid has the same
chemical properties as the blood group.
Point mutation
Missense Mutation
Sickle cell disease
Spontaneous mutation
Crop Variety
1. Rice GEB-24, Dee-Geo-Woo-Gen
2. Wheat NORIN
3. Groundnut TMV-10
4. Sorghum Co-4 (Coimbatore 4)
Induced mutation
Crop Mutant
variety
Original
variety
Mutagen
1. Rice JAGANNATH T-141 X-rays
MAHSURI
MUTANT
MAHSURI, g-rays
2. Wheat SHARBATI
SONARA
NP-836
SONARA 64
NP-799
UV rays
x rays
Muatation
Muatation
Muatation
Muatation
Muatation

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Muatation

  • 1.
  • 2. Submitted by VIKAS KUMAR SINGH M. SC. (Ag), Department of Genetics & Plant Breeding, Chaudhary Charan Singh University, Meerut Submitted to DR. S.S. Gaurav Asso. Professor, Department of Genetics& Plant Breeding, Chaudhary Charan Singh University, Meerut GENERAL GENETICS
  • 3.
  • 4. MUTATION IS HERITABLE CHANGES IN THE GENETIC MATERIAL THAT PROVIDE THE RAW MATERIAL FOR EVOLUTION.
  • 5.
  • 6.
  • 7.
  • 8.
  • 9. Classification OF MUTATION There are different ways of classifying mutation Functional Structural Harmful Beneficial Neutral Point Frame shift Silent Missense Nonsense
  • 10. Beneficial Mutation  Beneficial are the ultimate source of genetic variation. Raw material for evolution. For example, Protection against HIV infection
  • 11. Neutral Mutation A neutral mutation is a mutation that occurs in a amino acid codon but it has no impact. Wild-type AUG UUG CAG UGG UAA TAC AAC GTC ACC ATT M e t h - P h e n - G l n - T r p TAC gAC GTC ACC ATT AUG cUG CAG UGG UAA Meth leu gln trp A change in base pare results in an amino acid change but the new amino acid has the same chemical properties as the blood group.
  • 15. Crop Variety 1. Rice GEB-24, Dee-Geo-Woo-Gen 2. Wheat NORIN 3. Groundnut TMV-10 4. Sorghum Co-4 (Coimbatore 4)
  • 17. Crop Mutant variety Original variety Mutagen 1. Rice JAGANNATH T-141 X-rays MAHSURI MUTANT MAHSURI, g-rays 2. Wheat SHARBATI SONARA NP-836 SONARA 64 NP-799 UV rays x rays