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Life-hacking stress ”in the wild”
Pablo E. Paredes, PhD, MBA
On a daily basis…
overworked
tired
angry
overweight
unmotivated
distracted
unhappy
feeling isolated
1 in 4 people affected by mental 

or neurological disorders …
in the wild: 87% indoors & in cars
Pervasive Wellbeing Technology Lab
Keep people healthy with the
right intervention, at the right time.
Right intervention at the right time
Across multiple (indoor) scenarios
Could you estimate the efficiency of
mental health therapy?
Efficiency = (Adoption – Attrition) / Total
Efficacy = Successful completion
1/4
10%
20% 1/3
0.05%
of the Population

(0.22% Efficiency)
1/3
APA / UCSF Latino Mental Health / Mohr, D.
An open problem:
policy, medicine, design, data
Referral Dx Treated No Relapse
Quit business career to solve mental
health technology gap
Human Computer/Robot Interaction (HCI/HRI) 

Artificial Intelligence (AI)

Behavior Change

Biomechanics

Postdoc in Computer Science @ Stanford (HCI Group)
Computer Science PhD @ UC Berkeley (Berkeley Institute of Design)
About me …
Human health
World Health Organization (WHO) ’48:
“a state of complete physical, mental and
social well-being and not merely the absence
of disease or infirmity.”
Wellbeing
always
happened 

“in the wild”
21
Gambhir et al. Science Translational Medicine
Health is not the absence
of disease 

WHO ‘48
No economic incentives
Healthy people are NOT
motivated 

“too busy”, “let me be”
What about keeping people healthy?
22
Precision Health: Everyday tasks can be
equipped with smart devices
Gambhir et al. Science Translational Medicine
Modern wellbeing “in the wild”
60-80% of primary care visits due to
stress, 3% get stress management


69% say it is important to manage
stress but only 32% know what to do
42% of Americans lying awake at
night due to stress
[Nerukar, et al.] When Physicians Counsel About Stress: Results of a National Study,
JAMA Internal Medicine, (2013)

Stress in America, American Psychological Association, (2013)
Stress Management
Pervasive Wellbeing Technology Lab
Non-obtrusive
Sensing
(precision / use)
Subtle 

Interventions
(what? / when?)
Interventions are NOT an organic evolution of sensing
Engagement is NOT an evolution of precision
Efficiency is NOT an evolution of efficacy
New science of interventions in the wild
Medicine + Engineering + Design + Economics
Fundamental Challenges
Out of the lab and into the wild
People forget, get bored, and break stuff
Context & noise can turn

interventions into exacerbations
Project examples:
Moustress: stress detection w/ PC mouse
Fast & Furious: stress detection w/ steering w.
PopTherapy: AI stress micro-interventions Just Breathe: slow breathing while driving
Fiat Lux: affective & efficient urban lights
Non-obtrusive
Sensing
(precision / use)

Subtle
Interventions
(what? / when?)

29
Find people where they are…
Americans stuck in cars for 60 min/day
https://upload.wikimedia.org/wikipedia/commons/6/6d/TrafficJamFrustration.jpg
Turn this bug into a feature
Daily stress exacerbation
Work
Commute
Home
Daily stress exacerbation
Work
Sensing & Intervening
Commute
Home
Hidden sensors in the wild



sensing with 

Fast & Furious:Detecting Stress with a Car Wheel
Paredes, P. E., Ordoñéz, F., Ju, W., Landay, J. A., 

CHI 2018
Sun, D., Paredes, P. E., Canny, J., CHI 2014

Detection of stress-based muscle stiffness
differences in mouse motion via Mass Spring
Damper (MSD) model

MouStress: Detecting Stress 

from Mouse Motion
http://www.quickmeme.com/meme/3sp0z3
Peripheral Nervous System
Autonomic
Nervous System
Visceral motor
nuclei in
hypothalamus
------
Vision
Glands
Respiration
Digestions
Heart
Somatic 

Nervous System
Motor cortex &
motor nuclei of
brain stem
------
Skeletal muscle
Brain
Spinal cord
Central 

Nervous 

System
Electro-dermal Activity (EDA)
Autonomic sensing 

(Obtrusive)
Heart Rate Variability (HRV)
Fight or Flight

Autonomic + Somatic
Pupils dilate, tunnel
vision, constant
surveillance
Breathing becomes
fast and shallow
Heart beat is faster 

and noticeable
Increase sweating
Mouth
gets dry
Leg muscles become
tense and strengthened
Neck, shoulder
and arm
muscles become
tense and
stronger
The car: 

Non-obtrusive stress
sensor!
Subtle (just-in-time) interventions
Pop Culture:
Top Apps, Games, Media
Top Therapies:
Positive Psychology
Cognitive Behavioral
Meta Cognitive
Somatic
Everyone has something they do really well … find an
example on your Facebook timeline that showcases one of
your strengths.
http://www.facebook.com/me/


Affirmations always make me feel better. Here, check this
out.
http://m.pinterest.com/search/pins/?q=affirmation
Pop Therapy
Paradox: “Your stress app stresses me up!”
Paredes, P. E., Gilad-Bachrach, R., Czerwinski, M., Roseway, A., Rowan, K., Hernandez, J.

CHI 2014
Social
Network
CalmMeNow: Mobile stress Interventions
Paredes, P. E., Chan, M.
CHI 2011
Subtle interventions in a moving vehicle…
Manual Autonomous
Evaluating In-Car
Movements in the
Design of Mindful
Commute
Interventions:
Exploratory Study
Paredes, P. E., Hamdan, N.,
Cai, C., Clark, D., Ju, W.,
Landay, J. A.

Journal of Medical Internet
Research (JMIR) 2017
Just Breathe: In-Car Interventions for Guided 

Slow Breathing
Paredes, P. E., Zhou, Y., Balters, S., Murnane, E., Ju, W., Landay, J. A., 

Journal of Interactive, Mobile, Wireless, Ubiquitous Technology (IMWUT) 2018
Just Breathe… Slower
0 5 10 15 20 25 3012 18
NormalDeep
6
Our Goal: 30% reduction
Experts
"Pranayama”
Diaphragmatic
Risk of Exacerbation*
Novices
Lower rate
*Ahmed, B. et al., ReBreathe: A calibration protocol that improves stress/relax classification by relabeling deep breathing exercises, IEEE Affective Computing, 2016

Paredes, P., & Chan, M., CalmMeNow: Exploratory research and design of stress mitigating mobile interventions: CHI, 2011
Breaths Per
Minute (BPM)
Use the car to guide the body
41 Linear Resonant Actuator

50 dB, 13000±3000 RPM
*p < 0.05, **p < 0.01, ***p < 0.001
Treatment time
Normalizedandbaseline
correctedBreathingRate(BR)
*RMSSD increases = reduction in autonomic arousal
Treatment time
Normalizedandbaseline
correctedHRV(RMSSD)
Side effect: Sleepiness (autonomous driving)
50
What about fast breathing?
Breath Booster! Exploring In-car, Fast-paced Breathing
Interventions to Enhance Driver Arousal State
Balters, S., Murnane, E., Landay, J. A., Paredes, P. E., 

Pervasive Health 2018
52
BPM
12-18
https://www.youtube.com/watch?v=ZBjnograjq4
Hyperventilation
Normal
breathing
Breath of fire
0 20 40 60 80 100 120
Fast-
paced
Increase
Arousal
Ongoing work
54
Make the new wild 

look like the old wild
Driving with the Fishes: In-car calming 

virtual reality (VR) interventions
Ocean + Moving calmer
than Island + Sitting
(p<0.05)
Paredes, P. E., Balters, S., Qian, K., Murnane, E., Ordonez, F., Ju, W., Landay, J. A., 

Journal of Interactive, Mobile, Wireless, Ubiquitous Technology (IMWUT) 2018
Breaking the daily stress chain
Work
Commute
Home
(Non-obtrusive) Sensing
+

(Subtle) Intervening
Our approach revisited:
Non-obtrusive
Sensing
(precision / use)



Sensorless (repurpose signals)

Non-contact (radar/camera)

Skin-like (tatoos)
Subtle 

Interventions
(what? / when?)



Repurpose media (web/mobile)
Non-volitional (robotic furniture)

Subliminal (display/subwoofer)

Interstitial (commute)
Pre-
Intervention
Preparatory
Lower effect-size
Different scenario
(e.g. office ! car)
Integrated stress management
Workday Evening (pre-sleep)Commute
Cumulative daily stress
Reduced daily stressActive
Intervention
Ambient
Intervention
Ambient
Intervention
Pablo Paredes
Integrated wellbeing tech in the wild
Non-obtrusive stress w/ movement
Stress-aware conversational devices
Movement-based stress management Light-driven breathing/emotion regulation
Browser breathing
Sit-stand exercise & stress regulation
Non-obtrusive sensing
Subtle Interventions
Daily stress trajectories (a) Cumulative daily stress, (b) Reduced daily stress
Subliminal display Micro chatbots
Pablo E. Paredes

pparedes@stanford.edu
Pervasive Wellbeing Technology Lab
http://med.stanford.edu/pervasivewellbeingtech

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Dr. Pablo Paredes. Wellbeing Technology: Human Computer Interaction with Focus on Behavior Change

  • 1. Life-hacking stress ”in the wild” Pablo E. Paredes, PhD, MBA
  • 2. On a daily basis…
  • 11. 1 in 4 people affected by mental 
 or neurological disorders …
  • 12.
  • 13. in the wild: 87% indoors & in cars
  • 14. Pervasive Wellbeing Technology Lab Keep people healthy with the right intervention, at the right time.
  • 15. Right intervention at the right time Across multiple (indoor) scenarios
  • 16. Could you estimate the efficiency of mental health therapy? Efficiency = (Adoption – Attrition) / Total Efficacy = Successful completion
  • 17. 1/4 10% 20% 1/3 0.05% of the Population
 (0.22% Efficiency) 1/3 APA / UCSF Latino Mental Health / Mohr, D. An open problem: policy, medicine, design, data Referral Dx Treated No Relapse
  • 18. Quit business career to solve mental health technology gap Human Computer/Robot Interaction (HCI/HRI) 
 Artificial Intelligence (AI)
 Behavior Change
 Biomechanics
 Postdoc in Computer Science @ Stanford (HCI Group) Computer Science PhD @ UC Berkeley (Berkeley Institute of Design) About me …
  • 19. Human health World Health Organization (WHO) ’48: “a state of complete physical, mental and social well-being and not merely the absence of disease or infirmity.”
  • 21. 21 Gambhir et al. Science Translational Medicine Health is not the absence of disease 
 WHO ‘48 No economic incentives Healthy people are NOT motivated 
 “too busy”, “let me be” What about keeping people healthy?
  • 22. 22 Precision Health: Everyday tasks can be equipped with smart devices Gambhir et al. Science Translational Medicine
  • 23. Modern wellbeing “in the wild”
  • 24. 60-80% of primary care visits due to stress, 3% get stress management 
 69% say it is important to manage stress but only 32% know what to do 42% of Americans lying awake at night due to stress [Nerukar, et al.] When Physicians Counsel About Stress: Results of a National Study, JAMA Internal Medicine, (2013)
 Stress in America, American Psychological Association, (2013) Stress Management
  • 25. Pervasive Wellbeing Technology Lab Non-obtrusive Sensing (precision / use) Subtle 
 Interventions (what? / when?)
  • 26. Interventions are NOT an organic evolution of sensing Engagement is NOT an evolution of precision Efficiency is NOT an evolution of efficacy New science of interventions in the wild Medicine + Engineering + Design + Economics Fundamental Challenges
  • 27. Out of the lab and into the wild People forget, get bored, and break stuff Context & noise can turn
 interventions into exacerbations
  • 28. Project examples: Moustress: stress detection w/ PC mouse Fast & Furious: stress detection w/ steering w. PopTherapy: AI stress micro-interventions Just Breathe: slow breathing while driving Fiat Lux: affective & efficient urban lights Non-obtrusive Sensing (precision / use)
 Subtle Interventions (what? / when?)

  • 29. 29 Find people where they are…
  • 30. Americans stuck in cars for 60 min/day https://upload.wikimedia.org/wikipedia/commons/6/6d/TrafficJamFrustration.jpg
  • 31. Turn this bug into a feature
  • 33. Daily stress exacerbation Work Sensing & Intervening Commute Home
  • 34. Hidden sensors in the wild
 
 sensing with 

  • 35. Fast & Furious:Detecting Stress with a Car Wheel Paredes, P. E., Ordoñéz, F., Ju, W., Landay, J. A., 
 CHI 2018
  • 36. Sun, D., Paredes, P. E., Canny, J., CHI 2014
 Detection of stress-based muscle stiffness differences in mouse motion via Mass Spring Damper (MSD) model
 MouStress: Detecting Stress 
 from Mouse Motion http://www.quickmeme.com/meme/3sp0z3
  • 37. Peripheral Nervous System Autonomic Nervous System Visceral motor nuclei in hypothalamus ------ Vision Glands Respiration Digestions Heart Somatic 
 Nervous System Motor cortex & motor nuclei of brain stem ------ Skeletal muscle Brain Spinal cord Central 
 Nervous 
 System
  • 38. Electro-dermal Activity (EDA) Autonomic sensing 
 (Obtrusive) Heart Rate Variability (HRV)
  • 39. Fight or Flight
 Autonomic + Somatic Pupils dilate, tunnel vision, constant surveillance Breathing becomes fast and shallow Heart beat is faster 
 and noticeable Increase sweating Mouth gets dry Leg muscles become tense and strengthened Neck, shoulder and arm muscles become tense and stronger The car: 
 Non-obtrusive stress sensor!
  • 41. Pop Culture: Top Apps, Games, Media Top Therapies: Positive Psychology Cognitive Behavioral Meta Cognitive Somatic Everyone has something they do really well … find an example on your Facebook timeline that showcases one of your strengths. http://www.facebook.com/me/ 
 Affirmations always make me feel better. Here, check this out. http://m.pinterest.com/search/pins/?q=affirmation Pop Therapy Paradox: “Your stress app stresses me up!” Paredes, P. E., Gilad-Bachrach, R., Czerwinski, M., Roseway, A., Rowan, K., Hernandez, J.
 CHI 2014
  • 42. Social Network CalmMeNow: Mobile stress Interventions Paredes, P. E., Chan, M. CHI 2011
  • 43. Subtle interventions in a moving vehicle…
  • 44. Manual Autonomous Evaluating In-Car Movements in the Design of Mindful Commute Interventions: Exploratory Study Paredes, P. E., Hamdan, N., Cai, C., Clark, D., Ju, W., Landay, J. A.
 Journal of Medical Internet Research (JMIR) 2017
  • 45. Just Breathe: In-Car Interventions for Guided 
 Slow Breathing Paredes, P. E., Zhou, Y., Balters, S., Murnane, E., Ju, W., Landay, J. A., 
 Journal of Interactive, Mobile, Wireless, Ubiquitous Technology (IMWUT) 2018
  • 46. Just Breathe… Slower 0 5 10 15 20 25 3012 18 NormalDeep 6 Our Goal: 30% reduction Experts "Pranayama” Diaphragmatic Risk of Exacerbation* Novices Lower rate *Ahmed, B. et al., ReBreathe: A calibration protocol that improves stress/relax classification by relabeling deep breathing exercises, IEEE Affective Computing, 2016
 Paredes, P., & Chan, M., CalmMeNow: Exploratory research and design of stress mitigating mobile interventions: CHI, 2011 Breaths Per Minute (BPM)
  • 47.
  • 48. Use the car to guide the body 41 Linear Resonant Actuator
 50 dB, 13000±3000 RPM *p < 0.05, **p < 0.01, ***p < 0.001 Treatment time Normalizedandbaseline correctedBreathingRate(BR) *RMSSD increases = reduction in autonomic arousal Treatment time Normalizedandbaseline correctedHRV(RMSSD)
  • 49. Side effect: Sleepiness (autonomous driving)
  • 50. 50 What about fast breathing?
  • 51.
  • 52. Breath Booster! Exploring In-car, Fast-paced Breathing Interventions to Enhance Driver Arousal State Balters, S., Murnane, E., Landay, J. A., Paredes, P. E., 
 Pervasive Health 2018 52 BPM 12-18 https://www.youtube.com/watch?v=ZBjnograjq4 Hyperventilation Normal breathing Breath of fire 0 20 40 60 80 100 120 Fast- paced Increase Arousal
  • 54. 54 Make the new wild 
 look like the old wild
  • 55. Driving with the Fishes: In-car calming 
 virtual reality (VR) interventions Ocean + Moving calmer than Island + Sitting (p<0.05) Paredes, P. E., Balters, S., Qian, K., Murnane, E., Ordonez, F., Ju, W., Landay, J. A., 
 Journal of Interactive, Mobile, Wireless, Ubiquitous Technology (IMWUT) 2018
  • 56. Breaking the daily stress chain Work Commute Home (Non-obtrusive) Sensing +
 (Subtle) Intervening
  • 57. Our approach revisited: Non-obtrusive Sensing (precision / use)
 
 Sensorless (repurpose signals)
 Non-contact (radar/camera)
 Skin-like (tatoos) Subtle 
 Interventions (what? / when?)
 
 Repurpose media (web/mobile) Non-volitional (robotic furniture)
 Subliminal (display/subwoofer)
 Interstitial (commute) Pre- Intervention Preparatory Lower effect-size Different scenario (e.g. office ! car)
  • 58. Integrated stress management Workday Evening (pre-sleep)Commute Cumulative daily stress Reduced daily stressActive Intervention Ambient Intervention Ambient Intervention
  • 59. Pablo Paredes Integrated wellbeing tech in the wild Non-obtrusive stress w/ movement Stress-aware conversational devices Movement-based stress management Light-driven breathing/emotion regulation Browser breathing Sit-stand exercise & stress regulation Non-obtrusive sensing Subtle Interventions Daily stress trajectories (a) Cumulative daily stress, (b) Reduced daily stress Subliminal display Micro chatbots
  • 60. Pablo E. Paredes
 pparedes@stanford.edu Pervasive Wellbeing Technology Lab http://med.stanford.edu/pervasivewellbeingtech