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1. 3D PRINTING: ENVISIONING A
NEW ERA IN PHARMACEUTICAL
FIELD
PRESENTED BY: arnab mukherjee
SNEHASHIS SARKAr
COURSE: B. PHARM.

2. INTRODUCTION
3D Printed medicines
are revolutionising the
pharmaceutical market
as potential tools to
achieve personalised
treatments adapted to the
specific requirements of
each patient

3. HISTORY
3D printing is not as new
as we all think. In 2009
when the FDM patents
expired, 3D printing
became such a hot topic
that it was easy to
believe it was a brand
new innovation.

4. WHAT IS 3D PRINTING
Three-dimensional (3D)
printing is a process of
creating 3D objects,
where materials are
deposited layer over layer
using a computer-driven
process based on a digital
model.

5. EVOLUTION OF 3D
PRINTING
Fashion, toys
Automobile industry
Computer parts
Architectural industry
Medical
Pharmaceuticals, first
reported 3D pill in 1996

6. HOW IT CAME TO
PHARMACEUTICAL FIELD?
3D Printing
Technology Came into
Pharmaceutical Field
first 3D printed object,
a tiny cup for eye wash
Invented by Chuck
Hull in 1984

7. HOW IT WORKS?

8. 3D PRINTING METHODS
SOLID FREEFORM
FABRICATION (SFF)
PRINTING
BASED INJECT
SYSTEMS
DROP-ON-
DEMAND
PRINTING
(DOD)
DROP-ON-
SOLID
PRINTING
DROP-ON-
DROP
PRINTING
CONTINUO
US INJECT
SYSTEM
(CIJ)
NOZZLE-
BASED
DEPOSITION
SYSTEMS
WITH
MELTING
MATERIALS
FUSED-
DEPOSITION
MODELLING
(FDM)
WITHOUT
MELTING
MATERIALS
PRESSURE-
ASISTED
MICROSYRIN
GE (PAM)
LASER-
BASED
WRITTING
SYSTEMS
STEREOLOT
HOGRAPHY
(SLA)

9. PRINTING-BASED INJECT
SYSTEMS
Pressure flow
Droplet loading
device
Charged
Deflector
Drops for Printing

10. SYSTEMS
DOD CIJ

11. NOZZLE-BASED DEPOSITION
SYSTEMS
Rollers
Filament (Polymer+ API)
Temparature
Controlled unit
Nozzle

12. SYSTEMS
FDM PAM

13. LASER-BASED WRITTING
SYSTEMS
MIRROR
Inverted
Print bed

14. SYSTEMS
SLA

15. POLYMER USED
•Polyvinyl Alcohol (PVA)
•Poly Lactic Acid (PLA)
•Poly Caprolactone (PCL)

16. POLYVINYLALCOHOL
Polyvinyl alcohol (PVA)
is a thermoplastic
synthetic polymer with
good solubility in water,
low solubility in ethanol
and insoluble in many
organic solvents

17. POLY LACTIC ACID
Polylactic acid is a
biodegradable polymer
recognized as safe by
Food and Drug
Administration (FDA)
and suitable for different
medical applications.

18. POLYCAPROLACTONE
Polycaprolactone is a
semi-crystalline
hydrophobic polymer
whose crystallinity tends
to increase as its
molecular weight
decreases.

19. SMART MATERIALS FOR DRUG
DFELIVERY
Shape memory polymer
(SMP)s are considered
active polymers, as they
change from a temporary
shape to their original,
permanent shape upon
exposure to a stimulus.
Eg: methacrylate,
polyurethane.

20. APPLICATIONS
IN FASHION &
AUTOMOBILE 1.
2.

21. IN ARCHITECTURE
3.
4.

22. IN MEDICAL FIELD
5.
6.
7.
8.

23. IN PHARMACEUTICAL FIELD
9.
10.
11.

24. IN INDUSTRIES
IN WORLD-
•Hewlett-Packard (HP)
•Proto Labs
•Hershey’s
IN INDIA-
•Raspberry Pi and Arduino
•Nissan, Mahindra
•GKN Aerospace
•Aprecia Pharmaceuticals Company

25. ADVANTAGES
•Accurate dosing, lower side effects, better
paediatric adherence.
•Manufacture as per need and preference.
•No need for long shelf life.
•Individualized multi drug polypills.

26. LIMITATIONS
•Process is slow
•Fewer manufacturing jobs
•Limited materials
•3D printers are expensive

27. CONCLUSION
With continued research, it can be
believed that personalized
medicine will reach new levels of
possibility, and pharmacies will
be revolutionized by this
particular application of 3D
printing.

28. REFERENCES
•Norman J., Madurawe R. D., Moore C. M. V., Khan M. A.,
Khairuzzaman A., A new chapter in pharmaceutical
manufacturing: 3D-printed drug products, 2017, 108, 39–50.
• Andrea Alice Konta Marta García-Piña and Dolores R.
Serrano, Personalised 3D Printed Medicines: WhichTechniques
and Polymers Are More Successful? , 2017, 1.
•Fina F., Goyanes A., Gaisford S., Basit A.W., Selective laser
sintering (SLS) 3D printing ofmedicines. 2017, 529, 285–293.
•Woodruff M.A., Hutmacher W.D., The return of a forgotten
polymer—Polycaprolactone in the 21st Century. Prog. Polym.
Sci. 2010, 35, 1217–1256