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FIGURE 5- 1
Exposure routes for chemical agents in hazardous waste.
FIGURE 5-2
Overview of absorption, distribution, storage,
transformation, and elimination of a toxic substance in the
human body.
FIGURE 5-3
Types of doses for dermal contact with
contaminated soil.
FIGURE 5-4
Correlation of atmospheric benzene concentrations
with urinary phenol levels in workers in a rubber
coating plant.
FIGURE 5-5
Effect of dose fractionalization on
accumulation of a toxic compound.
FIGURE 5-6
Sequence of events leading up to a
toxic response.
FIGURE 5-7
Representative cellular targets for
toxic action.
FIGURE 5-8
Lock-and-key model for toxic
action.
FIGURE 5-9
Example of compounds with
identical molecular formula but
different toxicity.
FIGURE 5-10
Inhibition of enzyme
acetylcholinesterase (AChE) by
organophosphorus.
FIGURE 5-11
Dose-response relationship (dose
versus mortality).
FIGURE 5-12
Dose-response relationship for erythrocyte protoporphyrin (EP)
in blood as a function of the blood lead level in subpopulations.
FIGURE 5-13
Effect of EGM on the relative
organ weights of testes and
prostate.
FIGURE 5-14
Health effects from
breathing and/or
ingesting lead.
FIGURE 5-15
Health effects
from breathing
benzene.
FIGURE 5-16
Adequacy of human exposure data
on health effects of benzene.
FIGURE 5-17
Adequacy of animal test data on
health effects of benzene.
FIGURE 5-18
Location of NOAEL
and LOAEL doses with
respect to the threshold
on a typical dose-
response curve.
FIGURE 5-19
Three stages in carcinogenesis.
FIGURE 5-20
Metabolic activation of
benzo(a)pyrene.
FIGURE 5-21
Example of a
point mutation
through base
pair substitution.
FIGURE 5-22
2,3,7,8-
tetrachlorodibenzo(p)dioxin.
FIGURE 5-23
Hypothetical dose-
response curve for a
typical complete
carcinogen.
FIGURE 5-24
Extrapolation of dose-
response relationship
for liver tumors
induced by 2-
cetylaminofluorene in
the low-dose range.
FIGURE 5-25
Toxicological/ecological
relevance and time scale
of toxic responses for
levels of biological
organization.
FIGURE 5-26
Idealized plot of dose-response relationship.
FIGURE 5-27
Graphical
interpolation of time-
ependent LC50
values for sodium selenite.
FIGURE 5-28
Biomagnification of pesticides in
aquatic food chains.
FIGURE 5-29
Possible movement and fate of a
contaminant after absorption
into the bloodstream of fish.

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