This document discusses testicular seminoma, a type of germ cell tumor that originates in the testis. It describes the signs and symptoms, gross pathology, histopathology, immunohistochemistry, differential diagnosis, staging, and treatment protocol for testicular seminoma. Microscopically, seminoma appears as sheets of pale tumor cells separated by fibrovascular septae with lymphocytic infiltration and a characteristic "tigroid" background. Immunohistochemistry stains such as OCT3/4, CD117, and D2-40 are useful for diagnosis. Staging involves determining if the cancer has spread from the testis and treatment typically involves surgery followed by radiation or chemotherapy.

1. TESTICULAR TUMOR-
SEMINOMA
DR YLS

2. TESTIS HISTOLOGY

3. TESTICULAR TUMORS CLASSIFICATION

4. GERM CELL TUMORS

5. ETIOLOGY

6. SIGNS AND SYMPTOMS

7. TESTIS SELF EXAMINATION

8. GROSS PATHOLOGY
 WELL
DEMARKATED,HOMOGENOUS,SOLID,.
GREY WHITE TUMORS.
 SURFACE NODULARITY AND
LOBULATIONS MAY BE SEEN

9. HISTOPATHOLOGY
 SHEETS AND LOBULES OF TUMOR CELLS
SEPERTED WITH FIBROVASCULAR SEPTAE
 CYTOPLASM IS TYPICALLY PALE
(GLYCOGEN),ROUND CENTRAL NUCLEUS
WITH PROMINENT NUCLEOLI
 LYMPHOCYTIC INFILTERATION SEEN
 RARELY GERMINAL
CENTRES,ODEMA,CYSTIC
SPACES,GRANULOMAS,SYNCITIOTROPHO
BLASTS,FIBROSIS CAN BSEEN

10. HISTOPATHOLOGY

11. CLASSICAL AD SPERMATOCYTIC
SEMINOMA

12. CYTOLOGY
 DISCOHESIVE PATTERN OF LARGE CELLS
WITH MODERATE CYTOPLASM WITH
ROUND NUCLEUS AND PROMINENT
NUCLEOLI
 BACKGROUS SHOWS LYMPHOCYTIC
INFILTERATION
 CHAARECTERSITIC IS PRESCENCE OF
TIGROID BACKGROUND.
 SPECIAL STAIN-PAS POSITIVE

13. IMMUNOHISTOCHEMISTRY-
OCT3/4,CD117,D2-40,PLAP,SALL4

14. IHC IN TESTICULAR TUMORS

15. DIFFERNTIAL DIAGNOSIS
 EMBRYONAL CARCINOMA
 SPERMTOCYTIC TUMOR
 SERATOLI CELL TUMOR
 LYMPHOMA
 GRANULOMATOUS ORCHITIS

16. STAGING

17. TREATMENT PROTOCOL

18. 7/31/19