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Forecasting patient outflow from wards having
no real-time clinical data
Shivapratap Gopakumar
Truyen Tran, Wei Luo, Dinh Phung, Svetha Venkatesh
PPattern RRecognition aand DData AAnalytics
School of Information Technology
Deakin University, Australia
ICHI’16
Chicago
Introduction
Demand for Healthcare services increasing
2
“There is growing concern in various countries that the methods of providing
health care services are, if not already, approaching a level that will not be
sustained by the population.”
Mackay 2005; WHO report; European Commission report
Inpatient beds reduced by 2% since the last decade
 Increased levels of bed occupancy = high throughput to contain
costs
Efficient bed management is key to avoid bed crisis
Predicting discharge from ward
 Little attention for predicting
discharges from general wards
3
 Daily discharge rate = indicator of
efficiency
Ward Manager
Recovery ward
Current demand
Past experience
Number of beds needed
Can we provide a good estimate for total
next-day discharges from the ward?
 Significance: Relieve emergency
access block !
Challenges
4
No real-time clinical data.
Case-mix of patients in
ward.
 Non-linear hospital
dynamics.
Variation in data
Discharge pattern for each week
Each colour represents a week
Related Work
5
 Majority of studies on flow
in Emergency department.
 Other studies target wards
with real-time clinical data.
 To the best of our
knowledge, this is the first
study for open ward with
no real-time clinical data
Data
6
Tables in hospital database
Cohort details: Jan 2010 – Dec 2014
Min = 8.6 mins
Max = 44 days
Data: Patterns
7
Weekly discharge pattern Monthly discharge pattern
Daily discharges Time series decomposed to:
• Trend: long time change in mean level
• Seasonality: seasonal variations in the data
• Noise
Baseline Model: ARIMA
Autoregressive integrated moving average (ARIMA)
8
 able to capture trends and seasonal variations and update
the changes over time.
Forecasted Discharge at time t
sum of recent discharges sum of recent forecast errors
Our contribution:
Feature engineering and random forest
9
 Random Forest: creates an ensemble of decision trees
Tree 1
Tree n
 Tree bagging + random feature selection
= good prediction with great control on overfitting
10
Our contribution:
Feature engineering and random forest
We derived three groups of features from Ward data:
 Ward level, Patient level, Time series
 Ward-level features:
 Admissions: in past 7 days
Discharges: in past 7 days
Occupancy: in the previous day
11
Our contribution:
Feature engineering and random forest
 Patient-level features:
 Type of admission: 5 categories
 Unit referred from : 49 categories
 Patient class: 21 categories
 Age: 8 categories
# Wards visited: 4 categories
Elapsed length of stay for each patient
12
Our contribution:
Feature engineering and random forest
 Time-series features:
Seasonality: Current day-of-week, month, time-series
decomposition
 Trend: Polynomial regression
Experiment
• Baseline models: ARIMA, Naïve forecast (median
discharge)
• Compared with Random forest with our feature set
13
Experiment: Measuring performance
14
 Mean Forecast Error:
 Mean Absolute Error:
 Root mean square error:
 Symmetric Mean Absolute Percentage Error:
= True discharge at t = Forecasted discharge at t
Results
Random forest predictions:
 25% improvement over Naive forecasting
 17% improvement over ARIMA
 Least error for each day-of-week
15
RMSE
Discussion
16
Seasonality:
time-series decomposition
Number of patients in
ward, the previous dayPatients with only 1
ward visited before
current.
Number of males in
ward# dishcharges on prev
14th
dayForecasted trend using
polynomial regression
“Public Standard”
Discharges21 days
before
Elapse patient length
of stay
Discussion
17
RMSE
Fridays are easiest to predict
Saturdays are hardest to predict
Conclusion
1. Pronounced weekly patterns, as discussed in other studies
 suggests discharges are heavily influenced by
administrative reasons and staffing
1. Forecast performance is not as good as emergency/acute
care studies.
 But no clinical data available.
1. Proposed model built from commonly available data.
 Can be easily integrated into existing systems.
18
Thank you
19
References
• A. Kalache and A. Gatti, “Active ageing: a policy framework.” Advances in gerontology, vol. 11, pp. 7–18,
2002.
• M. Mackay and M. Lee, “Choice of models for the analysis and forecasting of hospital beds,” Health Care
Management Science, vol. 8, no. 3, pp. 221–230, 2005.
• M. Connolly, C. Deaton, M. Dodd, J. Grimshaw, T. Hulme, S. Everitt, and S. Tierney, “Discharge
preparation: Do healthcare professionals differ in their opinions?” Journal of interprofessional care, vol. 24,
no. 6, pp. 633–643, 2010.
• M. V. Shcherbakov, A. Brebels, N. L. Shcherbakova, A. P. Tyukov, T. A. Janovsky, and V. A. Kamaev, “A
survey of forecast error measures,” World Applied Sciences Journal, vol. 24, pp. 171–176, 2013.
• J. S. Peck, J. C. Benneyan, D. J. Nightingale, and S. A. Gaehde, “Predicting emergency department inpatient
admissions to improve same-day patient flow,” Academic Emergency Medicine, vol. 19, no. 9, pp. E1045–
E1054, 2012.
• S. Barnes, E. Hamrock, M. Toerper, S. Siddiqui, and S. Levin, “Real-time prediction of inpatient length of
stay for discharge prioritization” Journal of the American Medical Informatics Association, 2015.
• M. J. Kane, N. Price, M. Scotch, and P. Rabinowitz, “Comparison of arima and random forest time series
models for prediction of avian influenza h5n1 outbreaks,” BMC bioinformatics, vol. 15, p. 276, 2014.
• W. Luo, J. Cao, M. Gallagher, and J. Wiles, “Estimating the intensity of ward admission and its effect on
emergency department access block,” Statistics in medicine, vol. 32, no. 15, pp. 2681–2694, 2013.
20
Image credits
• Noun project:
– Benpixels
– Vinod Krishna
– Icon Fair
– Nikita Kozin
21

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Forecasting patient outflows without clinical data

  • 1. Forecasting patient outflow from wards having no real-time clinical data Shivapratap Gopakumar Truyen Tran, Wei Luo, Dinh Phung, Svetha Venkatesh PPattern RRecognition aand DData AAnalytics School of Information Technology Deakin University, Australia ICHI’16 Chicago
  • 2. Introduction Demand for Healthcare services increasing 2 “There is growing concern in various countries that the methods of providing health care services are, if not already, approaching a level that will not be sustained by the population.” Mackay 2005; WHO report; European Commission report Inpatient beds reduced by 2% since the last decade  Increased levels of bed occupancy = high throughput to contain costs Efficient bed management is key to avoid bed crisis
  • 3. Predicting discharge from ward  Little attention for predicting discharges from general wards 3  Daily discharge rate = indicator of efficiency Ward Manager Recovery ward Current demand Past experience Number of beds needed Can we provide a good estimate for total next-day discharges from the ward?  Significance: Relieve emergency access block !
  • 4. Challenges 4 No real-time clinical data. Case-mix of patients in ward.  Non-linear hospital dynamics. Variation in data Discharge pattern for each week Each colour represents a week
  • 5. Related Work 5  Majority of studies on flow in Emergency department.  Other studies target wards with real-time clinical data.  To the best of our knowledge, this is the first study for open ward with no real-time clinical data
  • 6. Data 6 Tables in hospital database Cohort details: Jan 2010 – Dec 2014 Min = 8.6 mins Max = 44 days
  • 7. Data: Patterns 7 Weekly discharge pattern Monthly discharge pattern Daily discharges Time series decomposed to: • Trend: long time change in mean level • Seasonality: seasonal variations in the data • Noise
  • 8. Baseline Model: ARIMA Autoregressive integrated moving average (ARIMA) 8  able to capture trends and seasonal variations and update the changes over time. Forecasted Discharge at time t sum of recent discharges sum of recent forecast errors
  • 9. Our contribution: Feature engineering and random forest 9  Random Forest: creates an ensemble of decision trees Tree 1 Tree n  Tree bagging + random feature selection = good prediction with great control on overfitting
  • 10. 10 Our contribution: Feature engineering and random forest We derived three groups of features from Ward data:  Ward level, Patient level, Time series  Ward-level features:  Admissions: in past 7 days Discharges: in past 7 days Occupancy: in the previous day
  • 11. 11 Our contribution: Feature engineering and random forest  Patient-level features:  Type of admission: 5 categories  Unit referred from : 49 categories  Patient class: 21 categories  Age: 8 categories # Wards visited: 4 categories Elapsed length of stay for each patient
  • 12. 12 Our contribution: Feature engineering and random forest  Time-series features: Seasonality: Current day-of-week, month, time-series decomposition  Trend: Polynomial regression
  • 13. Experiment • Baseline models: ARIMA, Naïve forecast (median discharge) • Compared with Random forest with our feature set 13
  • 14. Experiment: Measuring performance 14  Mean Forecast Error:  Mean Absolute Error:  Root mean square error:  Symmetric Mean Absolute Percentage Error: = True discharge at t = Forecasted discharge at t
  • 15. Results Random forest predictions:  25% improvement over Naive forecasting  17% improvement over ARIMA  Least error for each day-of-week 15 RMSE
  • 16. Discussion 16 Seasonality: time-series decomposition Number of patients in ward, the previous dayPatients with only 1 ward visited before current. Number of males in ward# dishcharges on prev 14th dayForecasted trend using polynomial regression “Public Standard” Discharges21 days before Elapse patient length of stay
  • 17. Discussion 17 RMSE Fridays are easiest to predict Saturdays are hardest to predict
  • 18. Conclusion 1. Pronounced weekly patterns, as discussed in other studies  suggests discharges are heavily influenced by administrative reasons and staffing 1. Forecast performance is not as good as emergency/acute care studies.  But no clinical data available. 1. Proposed model built from commonly available data.  Can be easily integrated into existing systems. 18
  • 20. References • A. Kalache and A. Gatti, “Active ageing: a policy framework.” Advances in gerontology, vol. 11, pp. 7–18, 2002. • M. Mackay and M. Lee, “Choice of models for the analysis and forecasting of hospital beds,” Health Care Management Science, vol. 8, no. 3, pp. 221–230, 2005. • M. Connolly, C. Deaton, M. Dodd, J. Grimshaw, T. Hulme, S. Everitt, and S. Tierney, “Discharge preparation: Do healthcare professionals differ in their opinions?” Journal of interprofessional care, vol. 24, no. 6, pp. 633–643, 2010. • M. V. Shcherbakov, A. Brebels, N. L. Shcherbakova, A. P. Tyukov, T. A. Janovsky, and V. A. Kamaev, “A survey of forecast error measures,” World Applied Sciences Journal, vol. 24, pp. 171–176, 2013. • J. S. Peck, J. C. Benneyan, D. J. Nightingale, and S. A. Gaehde, “Predicting emergency department inpatient admissions to improve same-day patient flow,” Academic Emergency Medicine, vol. 19, no. 9, pp. E1045– E1054, 2012. • S. Barnes, E. Hamrock, M. Toerper, S. Siddiqui, and S. Levin, “Real-time prediction of inpatient length of stay for discharge prioritization” Journal of the American Medical Informatics Association, 2015. • M. J. Kane, N. Price, M. Scotch, and P. Rabinowitz, “Comparison of arima and random forest time series models for prediction of avian influenza h5n1 outbreaks,” BMC bioinformatics, vol. 15, p. 276, 2014. • W. Luo, J. Cao, M. Gallagher, and J. Wiles, “Estimating the intensity of ward admission and its effect on emergency department access block,” Statistics in medicine, vol. 32, no. 15, pp. 2681–2694, 2013. 20
  • 21. Image credits • Noun project: – Benpixels – Vinod Krishna – Icon Fair – Nikita Kozin 21

Editor's Notes

  1. Our research is motivated by the rising demand for healthcare services. There has been an increased demand all over the world as is reflected by different studies. Population growth, increase in life expectancy, work force issues BUT number of beds are reducing. Could be due to better preventive measures, better services.
  2. Most studies focus on emergency/acute-care patient flow. These centers are rich in data and resources because hospital performance is measured using these indices. Daily discharge rate can be a potential real-time indicator of operational efficiency [Wong et al., 2010 ] Significance
  3. Data: Only admin data, no clinical information about patients. No info about medications, procedures, current diagnosis Patients come from different places: Direct admissions, from emergency, from other wards Hospital procedures are nonlinear: waiting for some service, tests etc.
  4. ARIMA is widely used for time series forecasting Popular due to : ease of formulation and interpretability AR term: forecasted discharge is regressed over previous discharges MA term: forecast error is linear combination of past discharge errors
  5. Ensemble method: Random decision forests correct for decision trees' habit of overfitting to their training set.
  6. RF can rank importance of features in a natural way.
  7. This “weekend effect” could be attributed to shortages in staffing, or reduced availability of services like sophisticated tests and procedures Future Work: 1. Incorporate nonlinear statistics of hospitals: holidays, staff planning/leaves, availability of tests etc.