Specifying the therapeutic objectives for treatment of IBD

1. Correlation Seminar
Presented by: Shiva Kumar Shrestha
Roll no: 6104
Date: 12 Magh, 2074 ( 26 January, 2018)
Nepalese Army Institute of Health Sciences-College of Medicine
GIT and Hepatobiliary System

2. Objective
• Specify the therapeutic objectives of treatment of inflammatory bowel
disease
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3. Inflammatory Bowel Disease (IBD)
• Chronic relapsing inflammatory disease
• Involve ileum, colon or both
• Idiopathic
• 2 types
1. Crohn’s Disease 2. Ulcerative Colitis
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4. Therapeutic objectives for treatment of IBD
• Can be broadly classified as:
1. Medical objectives
2. Surgical objectives
3. Non-medical objectives
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5. Medical objectives Surgical objectives Non-medical objectives
• To provide symptomatic
relief
• To correct the complications • To help the patient in
reducing physical and
emotional stress
• To reduce the inflammation
caused by mucosal immune
activation
• To remove the dysplastic
tissue for prevention of
cancer
• To help the patient to stop
smoking
• To induce and maintain
remission
• Guiding the patients to
maintain a good nutritional
status
• To enhance the mucosal
healing
• Guiding the patients to
improve quality of life
• To prevent further
complications
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Therapeutic objectives for treatment of IBD

6. References
• Davidson’s Principal and Practice of Medicine, 22th Edition by Walker,
Colledge, Ralston and Penman, 2013, Chapter: Page No: 897-907
• Selecting Therapuetic Targets in IBD, The American Journal of
Gastroenterology by Bemelman, Florino, Rubin and Stoker, Volume
110, September 2015
• Essentials of Medical Pharmacology, 7th Edition by K.D. Tripathi,
2015, Chapter: 48, Page No: 683-685
• The Pharmacological Basis of Therapeutics, 12th Edition by Goodman
and Gillman, 2013, Chapter:38, Page No:653-660
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7. Thank you