Persistent Pulmonary Hypertension (PPHN) is a serious neonatal condition where a newborn's lungs struggle to transition to normal function after birth. This leads to high blood pressure in the arteries of the lungs, making it difficult for the baby to get enough oxygen into their bloodstream. This condition requires prompt medical attention and interventions to support the baby's breathing and improve oxygenation. For more details visit the PPT document.

1. MANAGINGPERSISTENT
PULMONARYHYPERTENSION:
EFFECTIVESTRATEGIES
FORNEWBORNS

2. Managing persistent pulmonary hypertension (PPHN) in newborns
requires a comprehensive approach that addresses the unique
challenges and complexities associated with this condition. In this
article, we will explore effective strategies for the management of
PPHN, ensuring optimal care and improved outcomes for newborns.
Oxygen Therapy:
• Administer supplemental oxygen to maintain adequate oxygen
saturation levels.
• Monitor oxygen saturation continuously using pulse oximetry.
VentilationSupport:
• Consider mechanical ventilation with strategies like high-frequency
ventilation or synchronized intermittent mandatory ventilation (SIMV).
• Optimize ventilator settings to achieve adequate oxygenation and
ventilation while minimizing lung injury.

3. Nitric Oxide (NO) Therapy:
• Administer inhaled nitric oxide to dilate pulmonary
blood vessels and improve oxygenation.
• Continuously monitor response and adjust NO levels as
needed.
Surfactant Replacement:
• Administer exogenous surfactant to improve lung
compliance and alveolar stability.
• Optimize ventilation post-surfactant administration.
ECMO (Extracorporeal Membrane Oxygenation):
• Consider ECMO for severe cases unresponsive to
conventional therapy.
• Refer to a specialized ECMO center for expert
management.

4. Hemodynamic Support:
• Maintain appropriate systemic blood pressure to support pulmonary
perfusion.
• Use vasopressors or inotropes as necessary.
Temperature Regulation:
• Maintain a stable body temperature to prevent stress and reduce
oxygen consumption.
Sedation and Analgesia:
• Administer sedatives and analgesics to minimize stress and oxygen
consumption.
Fluid Management:
• Implement strict fluid management to avoid volume overload and
reduce pulmonary congestion.

5. Nutritional Support:
• Provide optimal nutrition to support growth and energy
requirements.
Close Monitoring:
• Monitor vital signs, blood gases, and clinical status
closely.
• Assess for signs of worsening respiratory distress, such
as increased work of breathing and decreased oxygen
saturation.
Collaborative Care:
• Involve a multidisciplinary team including
neonatologists, pediatric pulmonologists, cardiologists,
and respiratory therapists.
• Regularly review and adjust treatment strategies based
on the infant's response.

6. Family Support and Education:
• Provide emotional support to parents and caregivers.
• Educate them about the condition, treatment options,
and potential outcomes.
Transition to Oral Medications:
• Gradually transition from intravenous medications to
oral agents as the infant improves.
Follow-Up Care:
• Plan for long-term follow-up to monitor
developmental and respiratory outcomes.

7. IN CONCLUSION
Effective management of persistent pulmonary
hypertension in newborns requires early diagnosis,
optimized oxygenation, pharmacological interventions,
temperature regulation, nutritional support, a
collaborative multidisciplinary approach, and long -term
follow-up. By implementing these strategies, Pulmonary
Hypertension Specialists in Coimbatore can provide the
best possible care for newborns with PPHN, improving
their outcomes and quality of life.

8. Connect with us.
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info@sriramakrishnahospital.com
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www.sriramakrishnahospital.com