renal disease in children

1. Dr. Shami Pokhrel
MD. Pediatrics

4. Glomerular filtration rate and renal blood flow
are markedly reduced, often by 50-75%
Oliguria may occur because of leakage of
glomerular filtrate back into circulation across
the damaged tubular epithelium, renal
vasoconstriction and tubular obstruction from
impaction of casts and cellular debris