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“Supporting Education and Research in Statistics and Applied Mathematics to innovate the Future”
The Statistical and Applied Mathematical Sciences Institute
Program on Statistical, Mathematical,
and Computational Methods for Precision
Medicine (PMED)
“Supporting Education and Research in Statistics and Applied Mathematics to innovate the Future”
The Statistical and Applied Mathematical Sciences Institute
Program premise
Precision medicine: Evidence-based approaches to tailoring
treatment to patient characteristics
Fundamental: Quantitative methods for translating data into
information to guide treatment decisions
Quantitative methods: Diverse range of methods by statistical,
mathematical, and computational scientists
“Supporting Education and Research in Statistics and Applied Mathematics to innovate the Future”
The Statistical and Applied Mathematical Sciences Institute
Program premise
Goal of PMED: Foster collaborations among statistical,
mathematical, computational, and domain health scientists to forge
synthesis of approaches and thus innovative new data-driven
methodology for precision medicine through
• Workshops
• Interactions among long- and short-term visitors, locals
• Working groups
“Supporting Education and Research in Statistics and Applied Mathematics to innovate the Future”
The Statistical and Applied Mathematical Sciences Institute
Opening workshop:
First step: This workshop!
Workshop goal:
• Showcase the diversity of approaches to precision medicine being
taken across the quantitative sciences
• Highlight challenges and opportunities
• Form thematic working groups to address these
“Supporting Education and Research in Statistics and Applied Mathematics to innovate the Future”
The Statistical and Applied Mathematical Sciences Institute
Working groups
How they work:
• Finalized during this workshop
• Leader(s) and participants (need not have attended this workshop)
• Weekly meetings throughout 2018-2019 (local in-person and
remotely via WebEx, orchestrated by SAMSI)
• October: Theme, scope, specific goal(s) finalized
• Potential outcomes: Review articles, research publications,
software, materials for a short course, grant proposals, …
• Possible 2-day workshops for particularly active groups
“Supporting Education and Research in Statistics and Applied Mathematics to innovate the Future”
The Statistical and Applied Mathematical Sciences Institute
Working groups
Tentative themes: Final themes determined during workshop
• Integrated modeling strategies
• Improved data-driven sequential decision-making
• Inferential methods/uncertainty quantification
• mHealth
• Public health/use of observational data
• Subpopulation identification
• ???? – Be on the lookout this week for opportunities
“Supporting Education and Research in Statistics and Applied Mathematics to innovate the Future”
The Statistical and Applied Mathematical Sciences Institute
Working groups
Logistics:
• Wednesday, August 15: Introduction, more details
• Thursday, August 16 afternoon: Working group formation
• Friday, August 17 morning: Working group formation
“Supporting Education and Research in Statistics and Applied Mathematics to innovate the Future”
The Statistical and Applied Mathematical Sciences Institute
Workshop info
Restrooms: 2nd floor, down hallway on the left
Special request: NCSU Statistics PhD Qualifying Exam on 1st floor
until 1:30 pm on Monday and Tuesday; quiet please!
Meals: Light breakfast provided; lunch, dinner on your own
“Supporting Education and Research in Statistics and Applied Mathematics to innovate the Future”
The Statistical and Applied Mathematical Sciences Institute
Workshop info
Tonight @ 5:00 pm: NC ASA Social at Raleigh Beer Garden, 614
Glenwood Avenue (350+ beers on draft!)
Tomorrow @ 4:45 pm: Poster session and reception, SAS Hall 2nd
floor atrium (adult beverages, heavy hors d’ouevres)
Dining: Ask any local for recommendations; Raleigh has great
restaurants!
“Supporting Education and Research in Statistics and Applied Mathematics to innovate the Future”
The Statistical and Applied Mathematical Sciences Institute
Enjoy the Workshop!

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PMED Opening Workshop - Opening Workshop Remarks - Marie Davidian & Peter Mucha, August 13, 2018

  • 1.
  • 2. “Supporting Education and Research in Statistics and Applied Mathematics to innovate the Future” The Statistical and Applied Mathematical Sciences Institute Program on Statistical, Mathematical, and Computational Methods for Precision Medicine (PMED)
  • 3. “Supporting Education and Research in Statistics and Applied Mathematics to innovate the Future” The Statistical and Applied Mathematical Sciences Institute Program premise Precision medicine: Evidence-based approaches to tailoring treatment to patient characteristics Fundamental: Quantitative methods for translating data into information to guide treatment decisions Quantitative methods: Diverse range of methods by statistical, mathematical, and computational scientists
  • 4. “Supporting Education and Research in Statistics and Applied Mathematics to innovate the Future” The Statistical and Applied Mathematical Sciences Institute Program premise Goal of PMED: Foster collaborations among statistical, mathematical, computational, and domain health scientists to forge synthesis of approaches and thus innovative new data-driven methodology for precision medicine through • Workshops • Interactions among long- and short-term visitors, locals • Working groups
  • 5. “Supporting Education and Research in Statistics and Applied Mathematics to innovate the Future” The Statistical and Applied Mathematical Sciences Institute Opening workshop: First step: This workshop! Workshop goal: • Showcase the diversity of approaches to precision medicine being taken across the quantitative sciences • Highlight challenges and opportunities • Form thematic working groups to address these
  • 6. “Supporting Education and Research in Statistics and Applied Mathematics to innovate the Future” The Statistical and Applied Mathematical Sciences Institute Working groups How they work: • Finalized during this workshop • Leader(s) and participants (need not have attended this workshop) • Weekly meetings throughout 2018-2019 (local in-person and remotely via WebEx, orchestrated by SAMSI) • October: Theme, scope, specific goal(s) finalized • Potential outcomes: Review articles, research publications, software, materials for a short course, grant proposals, … • Possible 2-day workshops for particularly active groups
  • 7. “Supporting Education and Research in Statistics and Applied Mathematics to innovate the Future” The Statistical and Applied Mathematical Sciences Institute Working groups Tentative themes: Final themes determined during workshop • Integrated modeling strategies • Improved data-driven sequential decision-making • Inferential methods/uncertainty quantification • mHealth • Public health/use of observational data • Subpopulation identification • ???? – Be on the lookout this week for opportunities
  • 8. “Supporting Education and Research in Statistics and Applied Mathematics to innovate the Future” The Statistical and Applied Mathematical Sciences Institute Working groups Logistics: • Wednesday, August 15: Introduction, more details • Thursday, August 16 afternoon: Working group formation • Friday, August 17 morning: Working group formation
  • 9. “Supporting Education and Research in Statistics and Applied Mathematics to innovate the Future” The Statistical and Applied Mathematical Sciences Institute Workshop info Restrooms: 2nd floor, down hallway on the left Special request: NCSU Statistics PhD Qualifying Exam on 1st floor until 1:30 pm on Monday and Tuesday; quiet please! Meals: Light breakfast provided; lunch, dinner on your own
  • 10. “Supporting Education and Research in Statistics and Applied Mathematics to innovate the Future” The Statistical and Applied Mathematical Sciences Institute Workshop info Tonight @ 5:00 pm: NC ASA Social at Raleigh Beer Garden, 614 Glenwood Avenue (350+ beers on draft!) Tomorrow @ 4:45 pm: Poster session and reception, SAS Hall 2nd floor atrium (adult beverages, heavy hors d’ouevres) Dining: Ask any local for recommendations; Raleigh has great restaurants!
  • 11. “Supporting Education and Research in Statistics and Applied Mathematics to innovate the Future” The Statistical and Applied Mathematical Sciences Institute Enjoy the Workshop!