SOME INFORMATION ABOUT GENETIC DISORDER IN CATTLE,SHEEP,CHICKEN AND GOAT.

2. What is gene?
A distinct sequence of nucleotides
forming part of a
chromosome.(Hereditary material of
organisms)
What is genome?
the complete set of genes.

3. What is genetic disorder??
A disease or condition caused by an absent or defective gene
or by a chromosomal aberration.

4. Reasons behind genetic disorder………
It generally occurs due to mutation and inheritance. Mainly three reason which
are responsible for genetic disorder.
1. Monogenetic disorders are caused by a mutation in a single gene. The
mutation may be present on one or both chromosomes (one chromosome
inherited from each parent). Examples: sickle cell disease, cystic fibrosis.
Monogenic disorders are relatively rare.
2. Multifactorial inheritance disorders are caused by a combination of small
inherited variations in genes, often acting together with environmental
factors.Examples: Heart disease, diabetes, and most cancers.
3. Chromosome disorders are caused by an excess or deficiency of the genes
that are located on chromosomes, or by structural changes within
chromosomes.Examples: Down syndrome,Jacob syndrome.

5. Reasons behind genetic disorder………

6. Livestock animal and their importance
What is livestock animal?
Livestock are domesticated animals raised in an agricultural setting to produce
commodities such as food , fiber and labor.
Many by-products are come from animal origin have wider application in the
modern society.
Fresh meat and offal, game and poultry, meat products, processed animal
protein for human consumption, processed pet food or raw material for pet food
production, lard and rendered fats, animal casings, milk and milk products, eggs
and egg products, manure, blood and blood products, bones, bone products and
gelatine, hides and skins, bristles, wool, hair and leathers.

7. Livestock animal resource of bangladesh

8. Genetic disorder in livestock
We can see various types of genetic disorder in livestock and economically these
diseases are very important because these diseases can damage a whole
population of a livestock species.

9. Genetic disorders in cattle……….
DWARFISM
1. Several types were observed in Angus
and Hereford in the 1950’s and 1960’s.
Also diagnosed in Brahmans and Dexter
2. The mutation was identified at Iowa
State University, and is now testable.
3. Carrier bull was not widely used,
carriers are rare, believed to be a
spontaneous mutation.

10. Genetic disorders in cattle……….
Osteopetrosis (OS)
1. Commonly known as Marble
Bone.
2. Diagnosed in Red Angus and other
breeds.
3. Calves aborted 10 to 30 days
early
4. Calves have short lower jaw
5. Deletion in a gene identified on
chromosome 4

11. Genetic disorders in cattle……….
Tibia Hemimelia (TH)
1. Diagnosed in Shorthorns in 2000.
2. Calves born dead or die shortly
after birth.
3. Twisted legs, fused joints, hernia,
hole in skull, etc.
4. A different mutation in the same
gene was found in TKA Outcast,
born in 2001

12. Genetic disorders in cattle……….
Pulmonary Hypoplasia
With Anasarca (PHA)
1. Found in Maine-Anjou, some
Chianina and Shorthorn, also in
Dexter.
2. Mutation probably preceded
importation of Maines to the US.
3. Water-logged appearance, small
lungs, no lymph glands.
4. Missense mutation identified,
testable.

13. Genetic disorders in sheep……….
SPIDER LAMB
SYNDROME(SLS)
1. It cause skeletal deformities in
young lamb.
2. Abnormal long bent limb,twisted
spine,shallow bodies and long
neck are seen.
3. It causes for recessive allele
disorder.

14. Genetic disorders in sheep……….
Rectal prolapse
1. Most commonly associated with
meat type sheep.
2. Can be cured by surgery.
3. After surgery it also can be occur
again.

15. Genetic disorders in sheep……….
PROGANATHISM
1. Lower jaw is longer than
upper jaw.
2. Dosen’t get enough nutrition.
3. Cant eat food properly.

16. Genetic disorders in chicken……….
BENT TOES
1. The toe is banded.
2. Caused by recessive allele.
3. Also cause if the breeding bed is
too hot.

17. Genetic disorders in chicken……….
SPLIT-WING
1. Axial feather is missing.
2. Some bird show split wing in one
wing and normal in other wing.
3. Caused by simple recessikve
gene.

18. Genetic disorders in goat……….
EPIDERMOLYSIS BULLOSA
1. The goats presented with
exungulation, erosions, crusts
and scars on the skin and ulcers
in the oral cavity.
2. The disease has an autosomal
recessive mode of inheritance.
3. the skin showed subepidermal
separation with clefts filled.

19. Genetic disorders in goat……….
Fainting Goat
1. It is believed to be caused by
some sort of genetic mutation
impairing a person’s skeletal
muscle chloride channel.
2. The condition is involved with a
dysfunction of the chloride
conductibility.
3. Affected goat became paralysed
for some time.

20. PREVENTION OF GENETIC DISORDER……
Normally genetic disorder can not be cured by any medicine.Now a days some
vaccine and some type of surgery is available to cure genetic disorder.But cure Is
not enough for genetic disorder in livestock animal.We have to prevent those
disorder in order to save our economic stand.
The best way for prevention is selective breeding.We have to ignore in breeding
as much as possible because many of the genetic disorder express only in
homozygous form.If we found any disorder the animal should be culled from the
herd.its parent shouldn’t be used for further breeding.some test is also available
to identify the career organism.

21. CONCLUSION…..
As our country is agriculture-based that’s why our livestock animals play a vital
role in our economy. We can solve our poverty and unemployment problem
through livestock farming. So we have to more careful about their health.
In their health matter nothing is more important than genetic disorder.

22. THANK YOU LADIES AND GENTLE MAN
FOR YOUR PATIENCE
THE END