MB- Mitosis

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Razwan2

Mitosis, All related briefly.

Health & Medicine

Molecular Biology
Cell Division - Mitosis
Radwan Rushdi Mohammed
Rawand Dler Mohammed
Abdullah Yasin Bakr
Rebwar Adil Ismael
Rebaz Sabah Salah
Prepared by:
Ms. Azhin Saber Ali
Supervised by:

Mitosis
Interphase
• Cell Growth 🗸
• DNA replication 🗸
• Cell Function 🗸

Mitosis
Prophase
• Chromosomes condense
• Nuclear membrane
breaks down
• Centrosome/centrioles
help organize spindle
fibers

Mitosis
Metaphase
• Chromosomes easy to identify
• Nuclear membrane gone
• Chromosomes line up at center
• Spindle fibers link opposite
poles and chromosomes

Mitosis
Anaphase
• Spindle fibers shorten,
pulling sister chromatids
apart
• Each side of the cell has a
full set of chromosomes

Mitosis
Telophase
• Nuclear membrane re- forms in
each new cell
• Chromosomes un-coil
• Spindle and fibers dissolve
• Cytokinesis begins

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It is the process by which a parent cell divides into two or more daughter cells. Cell division usually occurs as part of a larger cell cycle. It is an essential biological process in many organisms. It is the means used by multicellular organisms in order to grow, repair, and reproduce. Types of Cell division: Mitosis Meiosis Mitosis: Mitosis is a division of the nucleus to produce two new daughter cells containing chromosomes identical to the parent cell. Phases of Mitosis: Mitosis is a continuous process and divided into different phases based on the appearance and behavior of the chromosomes. Prophase Prometaphase Metaphase Anaphase Telophase Cytokinesis 1.Prophase: Early prophase: During prophase chromatin (the complex of DNA and proteins contained in the nucleus), condense and become visible in a light microscope Nucleolus disappears & Paired centrioles move to opposite ends of the cell. The replicated chromosomes have an X shape and are called sister chromatids. The sister chromatids are joined at a point called the centromere. Late prophase: Nuclear membrane disappears a structure called the mitotic spindle begins to form at opposite ends of the cell (responsible for separating the sister chromatids into two cells) 2. Prometaphase: Prometaphase is the second stage of mitosis. In prometaphase, Chromosomes continue to condense Kinetochores appear at the centromeres Mitotic spindle attach to kinetochores Centrosomes move toward opposite poles 3. Metaphase: Metaphase is the third step in mitosis. Mitotic spindle is fully developed Sister chromatids line up at the spindle equator At the end of metaphase, the centromeres start to divide 4.Anaphase: Anaphase begin with the separation of the centromeres Sister chromatids together break down Sister chromatids (now called chromosomes) are pulled toward opposite poles The sister chromatids are drawn to opposite poles of the cell by contraction of spindle fibers 5.Telophase: Telophase begin when the two sets of daughter chromosomes have reached the two poles of the cell. The spindle fibers breaks down, The nuclear membrane forms around each set of daughter chromosomes and the nucleoli reappear The chromosomes uncoil and become less visible under the light microscope 6. Cytokinesis: Cytokinesis is the sixth and final step of mitosis & A cleavage furrow separates the daughter cells Cytokinesis is the process of cytoplasmic division to form two daughter cells. Cytokinesis takes place when the Cytoplasm divides and two cells with identical genetic material are formed Daughter Cells Meiosis: Meiosis Takes place in the Gametes of an organism People have a Chromosome count of 46 When an egg joins a sperm the count must stay at 46 to remain human So, the egg can only have 23 chromosomes, and the sperm can only have 23 chromosomes But, the integrity of the organism must be maintained. During Meiosis diploid cells are reduced to haploid cells Diploid (2n) to Haploid (n): During Meiosis gamete (sex

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Whooping cough is a highly contagious disease caused by pertussis bacteria and may lead to death, particularly in infants less than 12 months of age. Whooping cough is preventable but Although it can be prevented by routine vaccination, it still affects many people, it can have serious complications including death. Management is only supportive. The majority need to be vaccinated to help protect those too young to be vaccinated.

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