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SNAKE BITE
SNAKE BITE
Classification of snakes.
 Snake venom.
 Pathophysiology of snake bite.
 Clinical features of snake bite.
 Management of snake bite.
 Postmortem Findings.
 Medico legal importance.
CLASSIFICATION OF SNAKES
Basically two types:
1. Non-Poisonous.
2. Poisonous.
1. Elapids (Neurotoxic) e.g. Cobra, King Cobra,
Common Krait, Banded Krait and Coral
2. Viper (Vascuolotoxic) e.g. Pit Viper as Bambo
Snakes & Pit less Vipers as Russell's Viper and Saw
scaled viper
3. Sea Snakes (Myotoxic) found in vicinity of Sea
coasts
NON-POISONOUS SNAKE
POISONOUS SNAKE - COBRA
POISONOUS SNAKE - COBRA
COMMON SPECTACLED COBRA
(POISONOUS SNAKE)
POSIONOUS SNAKE
(SPITTING COBRA)
POISONOUS SNAKE
(COMMON KRAIT)
POISONOUS SNAKE
( BANDED KRAIT)
SEA-SNAKE (POSIONOUS)
POISONOUS SNAKE - VIPER
ANATOMY OF VENOM
APPRARUS
Fang: Upper marginal teeth are modified to form
fangs which are solid in non-poisonous snakes
and have a groove or channel in poisonous ones.
Fangs are connected to venom glands by means
of duct.
 Venom gland is modified parotid salivary gland
while venom is toxic saliva.
SNAKE VENOM
Appearance:
Clear transparent, amber tinted fluid –
becomes yellowish granular mass on drying –
retains activity for many years.
Contents:
About 20 components – 90% are proteins.
 Enzymes.
 Non-enzymatic polypeptide toxins.
 Non-toxic proteins.
Important enzymes are:
a. Lecithinase (phospholipase A2) is most
important and causes myotoxicity,
neurotoxicity, cardiotoxicity,
haemolysis and increased vascular
permeability.
b. Hyaluronidase – promotes spread of
venom.
c. L-amino acid oxidase – gives bright yellow
colour to venom.
CLINICAL FEATURES
OF
SNAKE BITE
SIGNS AND SYMPTOMS
• Local
• Neurotoxic
• Vasculotoxic & Hemotoxic
• Myotoxic
Local symptoms and signs in the bitten part
• fang marks
• local pain
• local bleeding
• inflammation (swelling, redness, heat)
• bruising
• lymph node enlargement
• blistering
• local infection, abscess formation
• necrosis
FANG MARKS
LOCAL SWELLING &
BLISTERING
TISSUE NECROSIS
BLEEDING FROM FANG MARKS
BLEEDING FROM GUMS
SUBCONJUNCTIVAL
HEMORRHAGES
NEUROTOXIC
• Mild local symptoms
• Weakness of legs
• Paralysis of muscles of face and throat
leading to difficulty in speaking and
swallowing
• Ptosis and paralysis of extraoccular
muscles
• Convulsions
• Respiratory paralysis and failure
BILATERAL PTOSIS
VASCULOTOXIC & HEMOTOXIC
• Fang marks, local swallowing, cellulitis,
blisters
• Damage to endothelium
• Lysis of RBC followed by nephritis with
hemoglobinurea
• Haemoptysis & Hemorrhages from orifices
• Convulsions (due to hemorrhage in brain)
• Collapse, Comma, Death
MYOTOXIC
• Sharp initial prick with minimal signs
• Generalized muscular pain
• Myoglobinurea (after 3 – 5 hours)
• Brown discoloration of urine
• Respiratory paralysis
Management of Snake bite
• Allaying Anxiety
• Prevention of spread of venom
• Rapid clinical assessment and
resuscitation
• Detailed clinical assessment and species
diagnosis
• Investigations/laboratory tests
• Antivenom treatment (Reduces mortality
from 40% to 10%)
ANTIVENOM TREATMENT
Indications:
1. Extensive local tissue damage
2. Signs of systemic poisoning e.g. Ptosis
Dose:
For adults 60ml given initially after test
dose (may cause anaphylactic shock)
1/3 given subcutaneously at bite site
1/3 given Intramuscularly
1/3 given intravenously
• If there is danger of reaction, it may be
used along with adrenaline, antihistamine
and corticosteriods.
TYPES OF ANTIVENOM
• Monovalent (specific)
• Polyvalent (if the species of snake is
unknown). It is effective against Cobra,
Common Krait, Russell’s viper and saw
scaled viper
POSTMORTEM FINDINGS
• Fang marks
• Local swelling and necrosis
• Asphyxial signs of death due to
respiratory failure
• Hemorrhages in the lungs, serous
membranes and endocardium
• Necrosis of renal tubules
MEDICO LEGALASPECTS
• Usually accidental
• Rarely homicidal
• Suicide by snake bite is also reported
in literature (e.g. Cleopatra)

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SNAKE BITE (Breif)F_1-2.ppt