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DR. DAVID GREENE
ARIZONA: THE POTENTIAL
AND PROMISE OF
ADIPOSE-DERIVED STEM
CELLS IN TREATMENT
ORIGIN AND
LOCATION:
ADSCs are found in abundance in adipose (fat) tissue.
While fat has traditionally been viewed primarily as a
storage form of energy, it's now understood to be a
complex, multifunctional organ that also serves as a rich
source of stem cells.
EXTRACTION: ADSCs are typically harvested from a patient's own fat tissue, often from areas
like the abdomen or thighs, through a procedure similar to liposuction. After
extraction, the adipose tissue undergoes processing to isolate and concentrate
the stem cells.
CHARACTERISTICS
ADSCs are multipotent, meaning they have the
ability to differentiate into various cell types.
While they can't become any type of cell in the
body (like pluripotent stem cells can), they can
differentiate into a variety of cell types related
to their origin, including fat cells, bone cells,
cartilage cells, and muscle cells.
They also secrete growth factors and cytokines
that can promote tissue healing and modulate
inflammation.
THERAPEUTIC
APPLICATIONS:
Due to their regenerative properties and their ability to
modulate the immune system, ADSCs are being researched for
a wide range of therapeutic applications. This includes
treatments for orthopedic injuries, autoimmune diseases,
cardiovascular diseases, and even aesthetic and reconstructive
procedures.
In cosmetic surgery, for example, ADSCs are sometimes used to
improve the outcomes of fat transfer procedures, promoting
graft survival
ADVANTAGES
OVER OTHER
STEM CELLS:
Abundance: Adipose tissue is abundant in
the body, and even a small amount of fat
can yield a significant number of stem cells.
Less Invasive Extraction: Extracting stem
cells from adipose tissue is relatively less
invasive compared to, for example, extracting
bone marrow stem cells.
Autologous Use: Since the stem cells are
often sourced from the patient's own body,
there's a reduced risk of immune rejection
when they are reintroduced after processing.
THANK
YOU

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Dr. David Greene Arizona: The Potential and Promise of Adipose-Derived Stem Cells in Treatment.pptx

  • 1. DR. DAVID GREENE ARIZONA: THE POTENTIAL AND PROMISE OF ADIPOSE-DERIVED STEM CELLS IN TREATMENT
  • 2. ORIGIN AND LOCATION: ADSCs are found in abundance in adipose (fat) tissue. While fat has traditionally been viewed primarily as a storage form of energy, it's now understood to be a complex, multifunctional organ that also serves as a rich source of stem cells.
  • 3. EXTRACTION: ADSCs are typically harvested from a patient's own fat tissue, often from areas like the abdomen or thighs, through a procedure similar to liposuction. After extraction, the adipose tissue undergoes processing to isolate and concentrate the stem cells.
  • 4. CHARACTERISTICS ADSCs are multipotent, meaning they have the ability to differentiate into various cell types. While they can't become any type of cell in the body (like pluripotent stem cells can), they can differentiate into a variety of cell types related to their origin, including fat cells, bone cells, cartilage cells, and muscle cells. They also secrete growth factors and cytokines that can promote tissue healing and modulate inflammation.
  • 5. THERAPEUTIC APPLICATIONS: Due to their regenerative properties and their ability to modulate the immune system, ADSCs are being researched for a wide range of therapeutic applications. This includes treatments for orthopedic injuries, autoimmune diseases, cardiovascular diseases, and even aesthetic and reconstructive procedures. In cosmetic surgery, for example, ADSCs are sometimes used to improve the outcomes of fat transfer procedures, promoting graft survival
  • 6. ADVANTAGES OVER OTHER STEM CELLS: Abundance: Adipose tissue is abundant in the body, and even a small amount of fat can yield a significant number of stem cells. Less Invasive Extraction: Extracting stem cells from adipose tissue is relatively less invasive compared to, for example, extracting bone marrow stem cells. Autologous Use: Since the stem cells are often sourced from the patient's own body, there's a reduced risk of immune rejection when they are reintroduced after processing.