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Gut Hormones - Appetite, mood and health
Natasha Kapoor
PhD Fellow,
Diabetes Complication Research
Centre,
University Coll...
Our body needs food as a source of fuel to power all
of its processes.
Digestion – Gastrointestinal system
Gastrointestina...
Journey of a Pizza Slice
Stomach
Ghrelin
Ghrelin
hunger
Wren, A. M., et al. (2001). "Ghrelin enhances appetite and increases food intake in
humans." J Clin Endocri...
How to achieve lower Ghrelin Levels ?
Ghrelin seems to be a hormone that can’t be
directly controlled with drugs, diets or...
Small Intestine
Hormone Cocktail
Cholecystokinin
Peptide tyrosine tyrosine
Glucagon like peptide- 1
Oxyntomodulin
CCK
Gallbladder to release a substance called bile
Bile- essential for the digestion and absorption of fat
decreases food ...
PYY
Released after a meal
Reduces food intake
Makes you feel full
Batterham, R. L., et al. (2002). "Gut hormone PYY3-36 ph...
GLP-1
Released after a meal
Reduces food intake
Makes you feel full
Naslund, E., et al. (1999). "Energy intake and appetit...
OXM
Released after a meal
Reduces food intake
Makes you feel full
Cohen, M. A., et al. (2003). "Oxyntomodulin suppresses a...
Two major roles for gut hormones
in appetite regulation
The release of gut hormones can modulate
normal hunger and satiety...
Hot topics in the field of research
Gut hormone infusion study
GLP-1 analogue
GLP-1 responders/non- repsonders
Gut Hormone...
How to achieve higher satiety gut
hormone levels ?
Protein
Healthy Fats
Fiber
Complex
carbohydrates
The Metabolic Medicine Laboratory, University College Dublin
are interested in recruiting volunteers for a study looking a...
Gut hormones - Appetite, Mood and Health
Gut hormones - Appetite, Mood and Health
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Gut hormones - Appetite, Mood and Health

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Natasha from UCD Metabolic Medicine department talks about her work on gut hormones, how they impact our hunger and some clinical trials being carried out in UCD currently.

http://www.ucd.ie/medicine/lifewithus/ourpeople/featuredstaff/professorcarelleroux/

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Gut hormones - Appetite, Mood and Health

  1. 1. Gut Hormones - Appetite, mood and health Natasha Kapoor PhD Fellow, Diabetes Complication Research Centre, University College Dublin
  2. 2. Our body needs food as a source of fuel to power all of its processes. Digestion – Gastrointestinal system Gastrointestinal hormones – help digest and absorb food
  3. 3. Journey of a Pizza Slice
  4. 4. Stomach Ghrelin
  5. 5. Ghrelin hunger Wren, A. M., et al. (2001). "Ghrelin enhances appetite and increases food intake in humans." J Clin Endocrinol Metab 86(12): 5992.
  6. 6. How to achieve lower Ghrelin Levels ? Ghrelin seems to be a hormone that can’t be directly controlled with drugs, diets or supplements. Avoid weight extremes Eat more protein Regular eating No skipping meals Maintain a stable weight
  7. 7. Small Intestine
  8. 8. Hormone Cocktail Cholecystokinin Peptide tyrosine tyrosine Glucagon like peptide- 1 Oxyntomodulin
  9. 9. CCK Gallbladder to release a substance called bile Bile- essential for the digestion and absorption of fat decreases food intake Little, T. J., et al. (2005). "Role of cholecystokinin in appetite control and body weight regulation." Obes Rev 6(4): 297-306.
  10. 10. PYY Released after a meal Reduces food intake Makes you feel full Batterham, R. L., et al. (2002). "Gut hormone PYY3-36 physiologically inhibits food intake." Nature 418(6898): 650-654.
  11. 11. GLP-1 Released after a meal Reduces food intake Makes you feel full Naslund, E., et al. (1999). "Energy intake and appetite are suppressed by glucagon-like peptide-1 (GLP-1) in obese men." Int J Obes Relat Metab Disord 23(3): 304-311.
  12. 12. OXM Released after a meal Reduces food intake Makes you feel full Cohen, M. A., et al. (2003). "Oxyntomodulin suppresses appetite and reduces food intake in humans." J Clin Endocrinol Metab 88(10): 4696-4701.
  13. 13. Two major roles for gut hormones in appetite regulation The release of gut hormones can modulate normal hunger and satiety. Obesity - 37% of Irish adults overweight, 24% obese Very high levels of gut hormones may be released to generate food dislike and nausea.
  14. 14. Hot topics in the field of research Gut hormone infusion study GLP-1 analogue GLP-1 responders/non- repsonders Gut Hormone Study
  15. 15. How to achieve higher satiety gut hormone levels ? Protein Healthy Fats Fiber Complex carbohydrates
  16. 16. The Metabolic Medicine Laboratory, University College Dublin are interested in recruiting volunteers for a study looking at the effect of food on gut hormones by consuming a buffet meal containing foods of your liking. If you are aged 18 years or over You may be eligible. You will be reimbursed for your travel ! Further Information: If you are interested and would like to know more, please contact Natasha Kapoor on 0838664102 or guthormonestudy@gmail.com

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