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PHARMACOLOGY OF METFORMIN
PRESENTED BY: PRAGYA BANKER
B.PHARM (IV TH YEAR)
Metformin
Metformin is an oral diabetes medicine that helps control blood sugar
levels. Metformin is used together with diet and exercise to improve
blood sugar control in adults with type 2 diabetes mellitus. Metformin is
sometimes used together with insulin or other medications, but it is not
for treating type 1 diabetes.
SIDE EFFECTS:
๏cool, pale skin
๏depression
๏difficult or labored breathing
๏dizziness
๏fast, irregular, pounding, or racing heartbeat or pulse
๏feeling of warmth
๏headache
๏increased hunger
๏increased sweating
๏nausea
๏nervousness
๏nightmares
USES
Commonly used to lower blood sugar levels,
has other therapeutic uses like treating polycystic ovarian syndrome,
Obesity and also has anti ageing properties.
INTERACTIONS
✓Interaction with Alcohol
Consumption of alcohol is not recommended during treatment Taking this
combination may cause a condition called lactic acidosis
✓ Interaction with disease
๏ Lactic acidosis
๏Cardiovascular risk
๏B12 deficiency
๏Hypoglycaemia
✓Interaction with drugs
๏Aspirin
๏Insulin
๏Ibuprofen
CONTRAINDICATIONS:
‣ Pregnancy
Despite metformin being a category C drug in pregnancy, data are
reassuring in terms of the risk of congenital anomalies. The product
information recommends that metformin be replaced with insulin.
‣ Breast-feeding
The product information does not recommend metformin during lactation.
However, as in pregnancy, the available data do not support withholding
metformin in breastfeeding women.

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Presentation 6

  • 1. PHARMACOLOGY OF METFORMIN PRESENTED BY: PRAGYA BANKER B.PHARM (IV TH YEAR)
  • 2. Metformin Metformin is an oral diabetes medicine that helps control blood sugar levels. Metformin is used together with diet and exercise to improve blood sugar control in adults with type 2 diabetes mellitus. Metformin is sometimes used together with insulin or other medications, but it is not for treating type 1 diabetes.
  • 3. SIDE EFFECTS: ๏cool, pale skin ๏depression ๏difficult or labored breathing ๏dizziness ๏fast, irregular, pounding, or racing heartbeat or pulse ๏feeling of warmth ๏headache ๏increased hunger ๏increased sweating ๏nausea ๏nervousness ๏nightmares
  • 4. USES Commonly used to lower blood sugar levels, has other therapeutic uses like treating polycystic ovarian syndrome, Obesity and also has anti ageing properties.
  • 5. INTERACTIONS ✓Interaction with Alcohol Consumption of alcohol is not recommended during treatment Taking this combination may cause a condition called lactic acidosis ✓ Interaction with disease ๏ Lactic acidosis ๏Cardiovascular risk ๏B12 deficiency ๏Hypoglycaemia ✓Interaction with drugs ๏Aspirin ๏Insulin ๏Ibuprofen
  • 6. CONTRAINDICATIONS: ‣ Pregnancy Despite metformin being a category C drug in pregnancy, data are reassuring in terms of the risk of congenital anomalies. The product information recommends that metformin be replaced with insulin. ‣ Breast-feeding The product information does not recommend metformin during lactation. However, as in pregnancy, the available data do not support withholding metformin in breastfeeding women.