Aseptic Technologies, established in 2002, focuses on innovative aseptic filling solutions for biopharmaceuticals, including technologies for handling cell and gene therapies, vaccines, and antibodies. Their AT-Closed Vial® technology allows biopharma manufacturers to efficiently fill and seal vials under aseptic conditions, and they have achieved significant milestones, including the installation of their 100th filling equipment by 2016. The company continues to enhance its offerings, ensure safety in aseptic operations, and expand its global presence.

1. FILLING SOLUTIONS
ASEPTIC TECHNOLOGIES

2. SAFER PARENTERALS
Over the years, BioPharmaceutical companies have taken
measures to provide the highest quality to their patient

3. Consequently, to ensure such level of quality,
huge, complex and risky equipment is operated
SAFER PARENTERALS
New products and
therapies have imposed
new manufacturing and
quality challenges

4. For that reason, Aseptic Technologies has been set up in 2002
SAFER PARENTERALS

5. For that reason, Aseptic Technologies has been set up in 2002
with the mission to bring innovative solutions to aseptic filling operations.
SAFER PARENTERALS

6. OUR EXPERTISE

7. Aseptic Filling Technology
(AT-Closed Vial® Technology)
OUR EXPERTISE

8. Aseptic Filling Technology
(AT-Closed Vial® Technology)
OUR EXPERTISE
Manufacturing of Kits
and Devices for Aseptic Filling

9. Aseptic Filling Technology
(AT-Closed Vial® Technology)
OUR EXPERTISE
Manufacturing of Kits
and Devices for Aseptic Filling
Aseptic Liquid Transfer
Systems

10. 100
2002
Creation of
Aseptic
Technologies
2003
Presentation of
the concept to
EMA and FDA
2005
Presentation
of validation
results to FDA
2007
Contract filling
approved at AT
by EMA
2009
1st equipment
installed in the
United States
2011
Skan group
collaboration
2013
80% of GSK
vaccines through
AT-Port™
2015
1st equipment
installed in
Japan
2016
100th equipment
installed
2010
1st equipment
installed in
Europe
ASEPTIC TECHNOLOGIES
MILESTONES

11. Our solutions are for years used for manufacturing of biopharmaceutical
products: cell&gene theapies, vaccines, antibodies…
USERS OF OUR TECHNOLOGY
POSITION IN THE WORLD

12. AT-CLOSED VIAL
®
TECHNOLOGY

13. AT-Closed Vial®
is supplied to
biopharma manufacturer
ready-to-fill and closed
AT-CLOSED VIAL® TECHNOLOGY
CONCEPT

14. AT-Closed Vial®
is supplied to
biopharma manufacturer
ready-to-fill and closed
And now inside grade A it will be:
1) Filled through the stopper
1
AT-CLOSED VIAL® TECHNOLOGY
CONCEPT

15. AT-Closed Vial®
is supplied to
biopharma manufacturer
ready-to-fill and closed
And now inside grade A it will be:
1) Filled through the stopper
2) Then re-sealed by a laser
1 2
AT-CLOSED VIAL® TECHNOLOGY
CONCEPT

16. And now inside grade A it will be:
1) Filled through the stopper
2) Then re-sealed by a laser
3) And capped
AT-Closed Vial®
is supplied to
biopharma manufacturer
ready-to-fill and closed
1 2
AT-Closed Vial®
is filled, capped
and ready for next
processing steps
1 2 3
AT-CLOSED VIAL® TECHNOLOGY
CONCEPT

17. …offering a solution easy to launch and to scale-up:
with a complete range
of vials formats (1-50ml)
AT-CLOSED VIAL® TECHNOLOGY
FILL&FINISH EQUIPMENT

18. MANUFACTURING OF KITS

19. AT-FILLING KIT™
Manufacturing of ready-to-use kits and devices for aseptic filling of
injectable products
AT-Filling Kit™ is
• clean assembly of tubing, needle and other elements
• supplied in double PE bags, Gamma irradiated
• standard or customized

20. ASEPTIC LIQUID TRANSFER

21. AT-PORT™
AT-PORT™ a smart connecting system allowing
safe liquid transfer across a wall between two areas
with different containment classifications
Combined with connector Gamma-Sart™
commercialized by

22. HIGHLIGHTS AND NEW HORIZONS

23. HIGHLIGHTS 2016
Our 100th filling
equipment installed
First users of
AT-Closed Vial® Technology
in Canada and Russia,
Scaling-up in Japan
First application of
AT-Closed Vial® Technology
in Nanomedicine by Midatech
Pharma (ES)
Automated Thawing device
by Biocision (US) is available

24. UPCOMING
…and much more.
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Rue Camille Hubert 7 | B-5032 Gembloux | Belgium
T. +32 81 409 465 | F. +32 81 409 41
www.aseptictech.com

25. 25
Copyright by Aseptic Technologies S.A., Gembloux, Belgium.
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Aseptic Technologies S.A. These materials may not be reproduced, distributed,
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permission of Aseptic Technologies S.A.
The status of the information, specifications and illustrations in this presentation is
indicated by the date given below. Aseptic Technologies S.A. reserves the right to make
changes to the technology, features, specifications, and design of the equipment
without notice.
Status: January 2017, Aseptic Technologies S.A., Gembloux, Belgium
DISCLAIMER