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Dr. Narayan Nay Perumal
LET’S TALK ABOUT DRUGS….
Dr Mahajan’s De-Addiction Clinic
OLITO Multi-Speciality Clinic/ RAD Diagnostics
CLEAN ROOM
#ExBox
http://drnay.in
WHAT IS DRUGS?
TERMS
ADDICTIONARY
Abuse – Excessive use
Misuse – Inappropriate use
Use/High – Inebriation
Using – “in” Active Addiction
Recovering – stopped using
Clean = Sober
Substance – any drug including alcohol, prescription drugs
Multi-Addict or Polysubstance – uses more than one
substance
WHAT ARE THE DRUGS YOU
KNOW?
SOFT DRUG
Soft drugs are not thought to cause
physical addiction.
While they do not cause physical addiction,
some of them may still lead to psychological
dependence.
• Marijuana (Ganja)
• Hashish
• Mescaline
• Psilocybin
• LSD
• Ayahuasca
• Iboga
• DMT
HARD DRUG
Hard drugs are drugs that lead to
physical addiction.
• Opiates (Heroin, hydrocodone,
oxycodone, morphine)
• Benzodiazepine (Diazepine, Valium,
alprazolam, clonazepam)
• Flunitrazepam (Rufilin),
• Lorazepam(Ativan),
• methamphetamine (meth)
• Cocaine
• GHB
• Alcohol
• Nicotine
HARD DRUGS AND LEGALITY
CANNABINOIDS
• Cannabis is a genus of flowering plants which
produces THC (Tetra-Hydro-Cannabinol)
• Almost No OVERDOSE
• Almost No WITHDRAWL
• Psychologically or Habitually Addictive
EFFECTS OF THC
EFFECTS OF THC
• Effects = “High”
• Euphoria
• Stress reduction
• Increased sensuality
• Heightened Senses
• Increased Appetite =
Munchies
• Increased Libido
• General feeling of well being
• Joviality
• Increased Episodic Memory
• Altered Perception of Space
and Time = Time Shakes
• Tunnel Vision
EFFECTS OF THC
• Anxiety
• Introspection
• Paranoia
• Thought Abstraction (which
have no physical basis)
• Thought Aberration (away
from normal thinking)
Symptoms:
• Paranoid ideas
• Thought Broadcasting
• Irrational Thinking
• Hallucinations
• Social Withdrawal
• Aggression
• Depersonalization
• De-realization
• Paranoia
CONSUMPTION OF THC
Marijuana=
GANJA=
Maal=
Kalli=
Toke=
Mary Jane=
POT=
WEED
Rolling Paper
Joint
CONSUMPTION OF THC
HASH=
Hashish=
Bombay Black=
Manala Cream=
Manali=
Tola=
CONSUMPTION OF THC
Pot Cookies
Pot Brownies
Hash Cookies
Hash Cake
BHANG
VAPING
SHIVA’S INDIA
• Acute intoxication of cannabis usually resolves unremarkably
within 4-6 hours and is best managed by the following measures:
• Frequent reassurance and maintenance of a nonthreatening environment
• Minimal stimuli
• Use of a specifically assigned nurse to calm the patient
• Judicious use of benzodiazepines when significant anxiety is present.
• Lorazepam is used for acute marijuana-associated panic or anxiety
symptoms.
MANAGEMENT
EMERGENCY
• Treatment depends on the clinical presentation, the age of the patient, and
the presence of other legal or illicit substances.
• Immediate management should be supportive, including cardiovascular and
neurological monitoring, and placement in a quiet room.
• Gastric decontamination is rarely indicated, but may be considered in
children younger than 16 years with a large ingestion less than 2 hours
prior to presentation. OR in surgical emergencies
• Patients who are agitated, with psychosis, or with significant anxiety should
be treated with benzodiazepines.
• Lorazepam is used for acute marijuana-associated panic or anxiety
symptoms.
MANAGEMENT
Cannabis Withdrawal Syndrome
• Anxiety
• Irritability
• Depressed mood
• Restlessness
• Disturbed sleep
• G-I symptoms and decreased appetite.
Most symptoms begin during the first week of abstinence and resolve after a
few weeks.
MANAGEMENT
MANAGEMENT
DEPENDING ON SEVERITY OF WITHDRAWAL SYMPTOMS
(Bioavailability of THC differs from person to person with age, sex, weight etc. No
correlate has been found between impairment and usage)
• Nefazodone (450mg/day OD) - Improved anxiety
• Fluoxetine (20-40mg/day Morning) - Reduced cannabis use *
• Rimonabant (90 mg/day) - Attenuated effects of cannabis (Banned in US & UK)
• Entacapone (200mg/day) - Reduced craving
• Buspirone (60mg/day) - Reduced craving and irritability
• Lithium (500mg/day) - Reduced cannabis use
• Anti-psychotics for managing underlying thought disorders in long time cannabis abuse
• Divalproex, Bupropion, Naltrexone WORSENS withdrawals.
GANJA PSYCHOSIS
Spiked/Laced – Adding substances
without the user’s knowledge
OPIODS
Opium (poppy tears) is the dried latex obtained from
the opium poppy
EFFECTS OF OPIOIDS
“आँख बंद,
मुंह खुला
…….गर्ुुला”
“CHEMICAL HOOKS”
EFFECTS OF OPIODS
CONSUMPTION OF OPIOIDS
Brown Sugar=
Brown=
Garad=
Smack
Heroin=
Purer form of
Brown Sugar
CONSUMPTION OF BROWN
SUGAR/ HEROIN
“Chasing” or
“Chasing the Dragon”
“Spot Chasing”
“Panni” or Foil
“Chaser”
CONSUMPTION OF BROWN
SUGAR
Brown + Distilled Water+ Inj. Avil+ Inj. Vit C
“Shooting/Shoot”
“Fixing/Fix”
CONSUMPTION OF BROWN
SUGAR
Smoking it –
“Loading” in cigarettes
WITHDRAWAL FROM BROWN SUGAR/ HEROIN
Increased sweating, lacrimation, rhinorrhoea, urinary frequency Diarrhoea,
abdominal cramps, nausea, vomiting Muscle spasm leading to headaches, back
aches, e.g. cramps, twitching, arthralgia Piloerection, pupillary dilatation,
elevated blood pressure, tachycardia Anxiety, irritability, dysphoria, disturbed
sleep, increased cravings for opioids
Do not Inject Naltrexone UNLESS IT’S A OVERDOSE
MANAGEMENT
MANAGEMENT
MANAGEMENT
MANAGEMENT
MANAGENENT
MANAGEMENT
HARM REDUCTION
• Needle Exchange Program
• Safe Injection Sites (SIS) or Drug Consumption Rooms (DCR)
• Opioid Replacement Therapy – Buprenorphine
• Methadone Clinic
• Heroin Maintenance Program
MANAGEMENT
• Clonidine (Tapering)
• Benzodiazepams
• NSAIDS
• Anti-Psychotics – Olanzapine
• Anti-Depressants – SSRI
• Injectable Tramadol Abuse reduce by 10% each day
TRAMADOL
MANAGEMENT
CODEINE
CODEINE
CODEINE
PRESCRIPTION MEDICINE ABUSE
EFFECTS
GLUE SNIFFING
Fevi-Bond
Paint Thinners/ Petrol/ Inhalants
“Huffing” “Bagging” “
• Slurred Speech
• Motor Incoordination
• Nausea, Vomitting
• Loss of Appetite
• Emotional Blunting
• Impaired Short Term Memory
EFFECTS
GLUE SNIFFING
NOT
A
GATEWAY
DRUG
BUT A
GET-AWAY
DRUG
COCAINE
Cocaine is a crystalline
alkaloid that is obtained from
the leaves of the coca plant.
• Stimulant of the Central Nervous System
• Increases Mental Alertness
• Feelings of well-being
• Momentary Euphoria
• Increased Energy
• Increased motor activity
• Increased feelings of competence
• Enhanced sensuality
• Restlessness
• Anxiety
• Paranoia
EFFECTS
EFFECTS
GLAMOUROUS
DRUG
CONSUMPTION OF COCAINE
Powder Cocaine=
Snow=
White=
Coca=
Coke
“Snorting”
“Lines”
CRACK COCAINE
Baking Soda +
Cocaine or
Lignocaine =
Crack Cocaine
“Free Basing”
• Smoked in Crack Pipes or Bongs
• More Addictive than Powder
• Effects Last Longer
CONSUMPTION OF COCAINE
“Freezing” – Applying cocaine to gums
“Coca-puff” – Cocaine in Cigarette
SPEED BALL
• Cocaine + Heroin
• Can be a cocktail of drugs
• Upper (Stimulant) + Downer (Depressant)
• Quick Tolerance
• Greater chances of Overdoses and deathIntravenous
Snorting/ Insufflation
Oral
MEPHEDRONE (MD)
Mephedrone is
a synthetic stimulant drug of
the amphetamine and cathinone classes.
MD, drone,M-CAT,[White Magic[
and meow meow
MD
• Was available online, recently banned in July 2012
• Many spurious products available as MD locally
EFFECTS
MD EPIDEMIC
• EMERGENCY – NO KNOWN ANTIDOTE
• Supportive Care
• Antipsychotics
• Check for Hyperthermia
MANAGEMENT
SPASMOPROXYVON
Dicycloverine/dicyclomine
• Relieves GI muscle spasms
• nonselective smooth
muscle relaxation,
• anticholinergic side effects
• Supportive / Symptomatic Treatment
• Psychological Help
MANAGEMENT
Other Prescription Medicines Widely Abuse:
• Fentanyl
• Nitrosun
• Modafinil
• Ketamine
DARK WEB / DARK NET
MARKETPLACE
Dark Web - the part of the World
Wide Web that is only accessible
by means of special software,
allowing users and website
operators to remain anonymous
or untraceable.
PARTY DRUGS
ECSTACY
E=
XTC=
Ezee=
Contains MDMA
Empathogenic Drug
MDMA
• Psychedelic Amphetamine
• MDMA is used less frequently than other stimulants
• typically less than once per week
• Mixed with water and sipped
• Also called Molly
• “Entactogenic” - increased empathy or feelings of closeness with others
• increased empathy or feelings of closeness with others
• Visual Distortions
• Increased emotionality
• infantile ideas
• Increased self-confidence, sociability and feelings of communication being easy or simple
• Bruxism (grinding and clenching of the teeth)
• Dehydration
• Insomnia
• Tachycardia
• Erectile Dysfunction
• Trismus or Lock Jaw
• Teratogenic
EFFECTS
LSD
THE LSD EXPERIENCE
• also known as acid, is a psychedelic drug
• animated sensory experience of
senses, emotions, memories, time,
and awareness for 6 to 14 hours, depending on
dosage and tolerance
• within 30 to 90 minutes after ingestion, the user
may experience anything from subtle changes in
perception to overwhelming cognitive shifts.
• “TRIPS” – Psychedelic Experience
• Auditory Distortions
• Synaesthesia
• Additional spatial or temporal dimensions
LSD EFFECTS
CONSUMPTION
“Blots or Blotter”
CONSUMPTION
“Drops”
Cubes
Comes in “powers” – doses
400 micrograms
800 micrograms
1200 micrograms
1600 micrograms
Increasing does not
prolong the effect but
intensifies it.
CONSUMPTION
“Microdots”
“Gels”
MANAGEMENT
Chlorpromazine (CPZ) “cuts” or
Stops LSD trip
Deaths are due to anxiety attack
Or accidental deaths involving
high places or road traffics
MAGIC MUSHROOMS
DMT /AYAHUASCA
Extreme Hallucinogens
“Spirit Molecules”
EFFECTS
NDPS ACT The Narcotic Drugs and Psychotropic Substances Act,1985,
were enacted with stringent provisions to curb this menace. The Act envisages
a minimum term of 10 years imprisonment extendable to 20 years and fine of
Rs. 1 lakh extendable up to Rs. 2 lakhs for the offenders.
LAW & DRUGS
Drug Small quantity Commercial quantity
Amphetamine 2 grams (0.071 oz) 50 grams (1.8 oz)
Charas 100 grams (3.5 oz) 1 kilogram (2.2 lb)
Cocaine 2 grams (0.071 oz) 100 grams (3.5 oz)
Ganja 1 kilogram (2.2 lb) 20 kilograms (44 lb)
Heroin 5 grams (0.18 oz) 250 grams (8.8 oz)
LSD 2 milligrams (0.031 gr) 100 milligrams (1.5 gr)
Methadone 2 grams (0.071 oz) 50 grams (1.8 oz)
Morphine 5 grams (0.18 oz) 250 grams (8.8 oz)
Opium 25 grams (0.88 oz) 2.5 kilograms (5.5 lb)
LAW IN INDIA
Anyone who contravenes the NDPS Act will face punishment based on the quantity of the banned substance.
•involves a small quantity, with rigorous imprisonment for a term which may extend to 1 year, or with a fine which may extend
to ₹10,000 (US$160) or both;
•a quantity lesser than commercial quantity but greater than a small quantity, with rigorous imprisonment for a term which may extend to 10 years
and with fine which may extend to ₹1 lakh (US$1,600);
•a commercial quantity, with rigorous imprisonment for a term which shall not be less than 10 years but which may extend to 20 years and also a
fine which shall not be less than ₹1 lakh (US$1,600) but which may extend to ₹2 lakh
•Repeat offenses upto 30 years
DRUG COURTS
Let’s talk about drugs

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Let’s talk about drugs

  • 1. Dr. Narayan Nay Perumal LET’S TALK ABOUT DRUGS…. Dr Mahajan’s De-Addiction Clinic OLITO Multi-Speciality Clinic/ RAD Diagnostics CLEAN ROOM #ExBox http://drnay.in
  • 4. ADDICTIONARY Abuse – Excessive use Misuse – Inappropriate use Use/High – Inebriation Using – “in” Active Addiction Recovering – stopped using Clean = Sober Substance – any drug including alcohol, prescription drugs Multi-Addict or Polysubstance – uses more than one substance
  • 5. WHAT ARE THE DRUGS YOU KNOW?
  • 6. SOFT DRUG Soft drugs are not thought to cause physical addiction. While they do not cause physical addiction, some of them may still lead to psychological dependence. • Marijuana (Ganja) • Hashish • Mescaline • Psilocybin • LSD • Ayahuasca • Iboga • DMT
  • 7. HARD DRUG Hard drugs are drugs that lead to physical addiction. • Opiates (Heroin, hydrocodone, oxycodone, morphine) • Benzodiazepine (Diazepine, Valium, alprazolam, clonazepam) • Flunitrazepam (Rufilin), • Lorazepam(Ativan), • methamphetamine (meth) • Cocaine • GHB • Alcohol • Nicotine
  • 8. HARD DRUGS AND LEGALITY
  • 9. CANNABINOIDS • Cannabis is a genus of flowering plants which produces THC (Tetra-Hydro-Cannabinol) • Almost No OVERDOSE • Almost No WITHDRAWL • Psychologically or Habitually Addictive
  • 11. EFFECTS OF THC • Effects = “High” • Euphoria • Stress reduction • Increased sensuality • Heightened Senses • Increased Appetite = Munchies • Increased Libido • General feeling of well being • Joviality • Increased Episodic Memory • Altered Perception of Space and Time = Time Shakes • Tunnel Vision
  • 12. EFFECTS OF THC • Anxiety • Introspection • Paranoia • Thought Abstraction (which have no physical basis) • Thought Aberration (away from normal thinking) Symptoms: • Paranoid ideas • Thought Broadcasting • Irrational Thinking • Hallucinations • Social Withdrawal • Aggression • Depersonalization • De-realization • Paranoia
  • 14. CONSUMPTION OF THC HASH= Hashish= Bombay Black= Manala Cream= Manali= Tola=
  • 15. CONSUMPTION OF THC Pot Cookies Pot Brownies Hash Cookies Hash Cake
  • 16. BHANG
  • 19. • Acute intoxication of cannabis usually resolves unremarkably within 4-6 hours and is best managed by the following measures: • Frequent reassurance and maintenance of a nonthreatening environment • Minimal stimuli • Use of a specifically assigned nurse to calm the patient • Judicious use of benzodiazepines when significant anxiety is present. • Lorazepam is used for acute marijuana-associated panic or anxiety symptoms. MANAGEMENT
  • 20. EMERGENCY • Treatment depends on the clinical presentation, the age of the patient, and the presence of other legal or illicit substances. • Immediate management should be supportive, including cardiovascular and neurological monitoring, and placement in a quiet room. • Gastric decontamination is rarely indicated, but may be considered in children younger than 16 years with a large ingestion less than 2 hours prior to presentation. OR in surgical emergencies • Patients who are agitated, with psychosis, or with significant anxiety should be treated with benzodiazepines. • Lorazepam is used for acute marijuana-associated panic or anxiety symptoms. MANAGEMENT
  • 21. Cannabis Withdrawal Syndrome • Anxiety • Irritability • Depressed mood • Restlessness • Disturbed sleep • G-I symptoms and decreased appetite. Most symptoms begin during the first week of abstinence and resolve after a few weeks. MANAGEMENT
  • 22. MANAGEMENT DEPENDING ON SEVERITY OF WITHDRAWAL SYMPTOMS (Bioavailability of THC differs from person to person with age, sex, weight etc. No correlate has been found between impairment and usage) • Nefazodone (450mg/day OD) - Improved anxiety • Fluoxetine (20-40mg/day Morning) - Reduced cannabis use * • Rimonabant (90 mg/day) - Attenuated effects of cannabis (Banned in US & UK) • Entacapone (200mg/day) - Reduced craving • Buspirone (60mg/day) - Reduced craving and irritability • Lithium (500mg/day) - Reduced cannabis use • Anti-psychotics for managing underlying thought disorders in long time cannabis abuse • Divalproex, Bupropion, Naltrexone WORSENS withdrawals.
  • 23. GANJA PSYCHOSIS Spiked/Laced – Adding substances without the user’s knowledge
  • 24. OPIODS Opium (poppy tears) is the dried latex obtained from the opium poppy
  • 25. EFFECTS OF OPIOIDS “आँख बंद, मुंह खुला …….गर्ुुला” “CHEMICAL HOOKS”
  • 27. CONSUMPTION OF OPIOIDS Brown Sugar= Brown= Garad= Smack Heroin= Purer form of Brown Sugar
  • 28. CONSUMPTION OF BROWN SUGAR/ HEROIN “Chasing” or “Chasing the Dragon” “Spot Chasing” “Panni” or Foil “Chaser”
  • 29. CONSUMPTION OF BROWN SUGAR Brown + Distilled Water+ Inj. Avil+ Inj. Vit C “Shooting/Shoot” “Fixing/Fix”
  • 30. CONSUMPTION OF BROWN SUGAR Smoking it – “Loading” in cigarettes
  • 31. WITHDRAWAL FROM BROWN SUGAR/ HEROIN Increased sweating, lacrimation, rhinorrhoea, urinary frequency Diarrhoea, abdominal cramps, nausea, vomiting Muscle spasm leading to headaches, back aches, e.g. cramps, twitching, arthralgia Piloerection, pupillary dilatation, elevated blood pressure, tachycardia Anxiety, irritability, dysphoria, disturbed sleep, increased cravings for opioids Do not Inject Naltrexone UNLESS IT’S A OVERDOSE MANAGEMENT
  • 37. HARM REDUCTION • Needle Exchange Program • Safe Injection Sites (SIS) or Drug Consumption Rooms (DCR) • Opioid Replacement Therapy – Buprenorphine • Methadone Clinic • Heroin Maintenance Program MANAGEMENT
  • 38. • Clonidine (Tapering) • Benzodiazepams • NSAIDS • Anti-Psychotics – Olanzapine • Anti-Depressants – SSRI • Injectable Tramadol Abuse reduce by 10% each day TRAMADOL
  • 45. GLUE SNIFFING Fevi-Bond Paint Thinners/ Petrol/ Inhalants “Huffing” “Bagging” “
  • 46. • Slurred Speech • Motor Incoordination • Nausea, Vomitting • Loss of Appetite • Emotional Blunting • Impaired Short Term Memory EFFECTS
  • 48. COCAINE Cocaine is a crystalline alkaloid that is obtained from the leaves of the coca plant.
  • 49. • Stimulant of the Central Nervous System • Increases Mental Alertness • Feelings of well-being • Momentary Euphoria • Increased Energy • Increased motor activity • Increased feelings of competence • Enhanced sensuality • Restlessness • Anxiety • Paranoia EFFECTS
  • 51. CONSUMPTION OF COCAINE Powder Cocaine= Snow= White= Coca= Coke “Snorting” “Lines”
  • 52. CRACK COCAINE Baking Soda + Cocaine or Lignocaine = Crack Cocaine “Free Basing” • Smoked in Crack Pipes or Bongs • More Addictive than Powder • Effects Last Longer
  • 53. CONSUMPTION OF COCAINE “Freezing” – Applying cocaine to gums “Coca-puff” – Cocaine in Cigarette
  • 54. SPEED BALL • Cocaine + Heroin • Can be a cocktail of drugs • Upper (Stimulant) + Downer (Depressant) • Quick Tolerance • Greater chances of Overdoses and deathIntravenous Snorting/ Insufflation Oral
  • 55. MEPHEDRONE (MD) Mephedrone is a synthetic stimulant drug of the amphetamine and cathinone classes. MD, drone,M-CAT,[White Magic[ and meow meow
  • 56. MD • Was available online, recently banned in July 2012 • Many spurious products available as MD locally
  • 59. • EMERGENCY – NO KNOWN ANTIDOTE • Supportive Care • Antipsychotics • Check for Hyperthermia MANAGEMENT
  • 60. SPASMOPROXYVON Dicycloverine/dicyclomine • Relieves GI muscle spasms • nonselective smooth muscle relaxation, • anticholinergic side effects
  • 61. • Supportive / Symptomatic Treatment • Psychological Help MANAGEMENT Other Prescription Medicines Widely Abuse: • Fentanyl • Nitrosun • Modafinil • Ketamine
  • 62. DARK WEB / DARK NET MARKETPLACE Dark Web - the part of the World Wide Web that is only accessible by means of special software, allowing users and website operators to remain anonymous or untraceable.
  • 65. MDMA • Psychedelic Amphetamine • MDMA is used less frequently than other stimulants • typically less than once per week • Mixed with water and sipped • Also called Molly • “Entactogenic” - increased empathy or feelings of closeness with others • increased empathy or feelings of closeness with others • Visual Distortions • Increased emotionality • infantile ideas • Increased self-confidence, sociability and feelings of communication being easy or simple
  • 66. • Bruxism (grinding and clenching of the teeth) • Dehydration • Insomnia • Tachycardia • Erectile Dysfunction • Trismus or Lock Jaw • Teratogenic EFFECTS
  • 67. LSD
  • 68. THE LSD EXPERIENCE • also known as acid, is a psychedelic drug • animated sensory experience of senses, emotions, memories, time, and awareness for 6 to 14 hours, depending on dosage and tolerance • within 30 to 90 minutes after ingestion, the user may experience anything from subtle changes in perception to overwhelming cognitive shifts. • “TRIPS” – Psychedelic Experience • Auditory Distortions • Synaesthesia • Additional spatial or temporal dimensions
  • 71. CONSUMPTION “Drops” Cubes Comes in “powers” – doses 400 micrograms 800 micrograms 1200 micrograms 1600 micrograms Increasing does not prolong the effect but intensifies it.
  • 73. MANAGEMENT Chlorpromazine (CPZ) “cuts” or Stops LSD trip Deaths are due to anxiety attack Or accidental deaths involving high places or road traffics
  • 77. NDPS ACT The Narcotic Drugs and Psychotropic Substances Act,1985, were enacted with stringent provisions to curb this menace. The Act envisages a minimum term of 10 years imprisonment extendable to 20 years and fine of Rs. 1 lakh extendable up to Rs. 2 lakhs for the offenders. LAW & DRUGS
  • 78.
  • 79. Drug Small quantity Commercial quantity Amphetamine 2 grams (0.071 oz) 50 grams (1.8 oz) Charas 100 grams (3.5 oz) 1 kilogram (2.2 lb) Cocaine 2 grams (0.071 oz) 100 grams (3.5 oz) Ganja 1 kilogram (2.2 lb) 20 kilograms (44 lb) Heroin 5 grams (0.18 oz) 250 grams (8.8 oz) LSD 2 milligrams (0.031 gr) 100 milligrams (1.5 gr) Methadone 2 grams (0.071 oz) 50 grams (1.8 oz) Morphine 5 grams (0.18 oz) 250 grams (8.8 oz) Opium 25 grams (0.88 oz) 2.5 kilograms (5.5 lb) LAW IN INDIA Anyone who contravenes the NDPS Act will face punishment based on the quantity of the banned substance. •involves a small quantity, with rigorous imprisonment for a term which may extend to 1 year, or with a fine which may extend to ₹10,000 (US$160) or both; •a quantity lesser than commercial quantity but greater than a small quantity, with rigorous imprisonment for a term which may extend to 10 years and with fine which may extend to ₹1 lakh (US$1,600); •a commercial quantity, with rigorous imprisonment for a term which shall not be less than 10 years but which may extend to 20 years and also a fine which shall not be less than ₹1 lakh (US$1,600) but which may extend to ₹2 lakh •Repeat offenses upto 30 years