Chelators otherwise called chelants, chelating agents or sequestering agents, are substances or compounds that bind to metal ions to form stable and water-soluble complexes that can easily be excreted from the body system. If you may recall metabolism of drugs in Pharmacology or Toxicology, you will realize that the whole purpose of metabolism of drugs is to change them from the hydrophobic (water-hating) state which can easy be absorbed by body cells into the more hydrophilic (water-loving) ones that can easily be excreted by the body. This is based on the fact that cells are surrounded by very hydrophobic structures. These structures only allow hydrophobic molecules or at least very tiny hydrophilic molecules to penetrate. As such chelators are used for heavy metal poisoning such as Iron, Lead, Mercury, Cadmium, Arsenic, et cetera. They are also known to work for common medical problems such as cardiovascular diseases. This presentation will define chelators, give their classifications, examples and what they are used for.