DEFINITION INTRODUCTION EPIDEMIOLOGY SYMPTOMS STAGING TREATMENT RISK FACTOR

1. GALGOTIAS
UNIVERSITY SUBMITTED TO – DR. YASH
PRATAP SIR
DEPARTMENT OF
PHYSIOTHERAPY
Topic – Define
Hodgkin’s
Lymphoma
Subject- Medicine with Paediatrics
and Geriatrics
PRESENTED BY –
1. SAURABH RAJ
2. RAKHI
3. MOHAMMAD HAMMAD KHAN
4.MUSKAN KUMARI
5.VANDANA YADAV

2. Definition
Introduction
Epidemiology
Symptoms
Diagnosis
Staging
Treatment
Risk Factor

3. MALIGNANT LYMPHOMA IS A TERM GIVEN TO TUMOURS OF THE
LYMPHOID SYSTEM AND SPECIFICALLY OF LYMPHOCYTES AND
THEIR PRECURSOR CELL I.E. CANCER OF THE LYMPHATIC
SYSTEM.
→MANY LYMPHOMAS ARE KNOW TO BE DUE TO SPECIFIC
GENETIC MUTATIONS.

8. SYMPTOMS –
SIGNS AND SYMPTOMS OF HODGKIN’S LYMPHOMA MAY INCLUDE-
~PAINLESS SWELLING OF LYMPH NODES IN YOUR NECK , ARMPITS
OR GROIN
~PERSISTENT FATIGUE
~FEVER
~NIGHT SWEATS
~UNEXPLAINED WEIGHT LOSS
~SEVERE ITCHING
~INCREASED SENSITIVITY TO THE EFFECTS OF ALCOHOL OR PAIN
IN YOUR LYMPH NODES AFTER DRINKING ALCOHOL

10. 1. CLASSICAL HODGKIN'S LYMPHOMA-
CLASSICAL HODGKIN'S LYMPHOMA IS THE MORE COMMON
TYPE OF THIS DISEASE.
. DIAGNOSED WITH THIS DISEASE HAVE LARGE, ABNORMAL
CELLS CALLED REED-STERNBERG CELLS IN THEIR LYMPH
NODES.

11. 2. NODULAR LYMPHOCYTES – PREDOMINANT HODGKIN’S LYMPHOMA-
. THIS MUCH RARER TYPE OF HODGKIN'S LYMPHOMA INVOLVES
LARGE, ABNORMAL CELLS THAT ARE SOMETIMES CALLED POPCORN
CELLS BECAUSE OF THEIR APPEARANCE.
. THIS TYPE OF HODGKIN'S LYMPHOMA MAY HAVE A BETTER CHANCE
OF A CURE WHEN THE DISEASE IS DIAGNOSED AT AN EARLY STAGE.

12. DIAGNOSIS
 The following test may be done :
. Imaging tests , such as x – rays or CT scans
 . Lymph node biopsy , which involves removing a pieces of lymph
node tissue to test for the presence of abnormal cells .
.Immunophenotyping to determine the type of lymphoma cells that are
present
. lung function tests to determine how well your lungs are working
.an echocardiogram to determine how well your heart is working
.bone marrow biopsy, which involves the removal and examination of
marrow inside your bones to see if the cancer has spread.

17. STAGING

18. RISK FACTOR
 EBV (Mixed Cellularity Subtype)
 Family History of HL
 Low Socio Economic Status

19. LONG TERM COMPLICATION
 Secondary Malignancy
 Cardiac Toxicity
 Pulmonary Dysfunction
 Thyroid Dysfunction
 Gonadal Dysfunction & Fertility
 Growth Retardation
 Psychosocial Problems