Mathilde LEPOITEVIN is a PhD candidate in physical chemistry at Institut Européen des Membranes, Université Montpellier. Her research focuses on designing single solid-state nanopores for mimicking biological channels and biomacromolecule detection. She has experience in nanopore functionalization, nanoscale biophysics, and nano-electrochemistry. Lepoitevin has authored or co-authored 11 papers and 4 conference proceedings related to her work on nanopores and biomolecule translocation. She is currently working on combining sensing and pH-gated functions in a single nanopore using an avidin-biotin system.

1. Mathilde LEPOITEVIN
PhD candidate
Institut Européen des Membranes, Université Montpellier,
2 Place Eugène Bataillon, 34095 Montpellier Cedex 5, France
 Mail : mathilde.lepoitevin@gmail.com
 Phone : (+33) 667 212 491
PROFESSIONAL EXPERIENCES
PhD student Physical-Chemistry 2013-expected 2016
Université Montpellier 2, Institut Européen des Membranes, Montpellier, France.
Design of single solid-state nanopore for mimicking biological channel and bio-macromolecules
detection.
Advisors: Dr. Sébastien Balme, Dr. Mikhael Bechelany
Visiting PhD Student 29.06.2015 – 15.08.2015
Deakin University, Institute for Frontier Materials, Waurn Ponds VIC, Australia.
Preparation and characterization of Au-SiN solid-state single nanopore, by combining Electron
Microscopy and Focused Ion Beam Microscopy
Advisor: Dr. Ludovic Dumee
Internship 04.02.2013 – 06.09.2013
CIC EnergiGUNE, Power Storage; Batteries and Supercaps, Araba, Spain.
Study of the conduction properties of NaxFePO4 as a cathode material for advanced Na-ion batteries.
Advisors: Pr. Dr. Teófilo Rojo, Dr. Damien Saurel.
Internship, M1 02.07.2012 – 28.09.2012
Université Montpellier 2, Institut Charles Gerhardt, Montpellier, France.
Study of ionic transport through an hybrid biological/artificial membrane.
Advisor: Dr. Sébastien Balme
Internship 03.05.2010 – 02.09.2011
Université Montpellier 2, Institut Charles Gerhardt, Montpellier, France.
Adsorption of proteins onto homo-ionic montmorillonite: Influence of the interlayer cations.
Advisor: Dr. Sébastien Balme
EDUCATION
MSc Chemistry 2013
Erasmus Mundus Master Program MESC Material for Energy Storage and Conversion
(Université de Picardie Jules Verne, Amiens, France (coordination university), Aix-Marseille Université,
Marseille, France (semester 1), Warsaw University of Technology, Warszawa, Poland (semester 2),
Universidad de Cordoba, Córdoba, Spain (semester 3), CIC Energigune, Miñano, Spain (semester 4))
BSc Physical-Chemistry 2011
Université Montpellier 2
MENTORING
Yixuan Zhao: (Master 2) 2016
Functionalization of single nanopores based on layer-by-layer polyelectrolyte self-assembly.
Bastien Jamilloux: (1st year engineering school ENSCM) 2015
Functionalization of single nanopores based on layer-by-layer polyelectrolyte self-assembly.
Marie Lemouel: (Master 1) 2014
Study of nanoparticles/poly-nucleotides interactions.

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PROFESSIONAL SKILLS
Research interests: solid-state nanopores, nanopore functionalization, nanoscale biophysics
Nano-electrochemistry and resistive pulse: Amplifier HEKA
Single nanopore production: track-etched method, SEM-FIB
Surface chemistry: ALD, CVD, PVD, bio-conjugate chemistry, self-assembly chemistry
Characterization: DLS, contact angle, SEM, FIB
Computer software: Origin, QuickFit, ImageJ, Fitmaster (HEKA), Patchmaster (HEKA)
Generic skills: student mentoring, scientific papers and project proposal writing, set up rational
implementation plan, improve upon original strategy
Soft skills: Tenacity, rigor, boldness, adaptability and intellectual flexibility, curiosity
GRANTS AND SCHOLARSHIPS
 PhD scholarship from the French government October 2013 – September 2016
 Collaboration work allocation, from doctoral school “Sciences Chimiques Balard” and the
“Chaire Total de la Fondation Balard” June – August 2015
 Study scholarship CIC EnergiGUNE September 2011 – September 2013
 Mobility grant Philéas, internship abroad scholarship February – September 2013
 Mobility grant Philéas, study abroad scholarship February – June 2012
OTHER ACTIVITIES
 Member of the laboratory council at “Institut Européen des Membranes” since 2015
 Member of the doctoral school “Sciences Chimiques Balard” council since 2014
 Students representative, Erasmus Mundus programme, MESC8 2011-2013
Language Research
French: Native. 11 Articles, 4 Proceedings
English: Bilingual (TOEFL: 105/120) 11 Oral communications (7 international, 6 national)
Spanish: Basic competency 7 Posters (6 international, 1 national)
REFERENCES
Dr. Sébastien Balme # +33 (0)467 149 118, mail : sbalme@univ-montp2.fr
Advisor of my PhD, Université Montpellier , Institut Européen des Membranes, Montpellier,
France
Dr. Mikhael Bechelany # +33 (0)467 149 167, mail : mikhael.bechelany@univ-montp2.fr
Co-advisor of my PhD, Université Montpellier , Institut Européen des Membranes, Montpellier,
France
Dr. Ludovic Dumee # +61 352 271 038, mail : ludovic.dumee@deakin.edu.au
Advisor of my doctoral internship at Deakin University, Institute for Frontier Materials, Waurn
Ponds VIC, Australia
Dr. Damien Saurel # +34 945 297 108, mail : dsaurel@cicenergigune.com
Advisor of my Master internship, CIC EnergiGUNE, Power Storage; Batteries and Supercaps,
Araba, Spain

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RESEARCH
Papers
1. A. Saracibar, J. Carrasco, D. Saurel, M. Galceran, B. Acebedo, H. Anne, M. Lepoitevin, T. Rojo, M.
Casas-Cabanas , Sodium insertion-extraction in the olivine NaxFePO4 (0 ≤ x ≤ 1) from First-Principles
Calculations. Phys. Chem. Chem. Phys., 2016, DOI: 10.1039/C6CP00762G IF 4.493
2. M. Lepoitevin, B. Jamilloux, M. Bechelany, E. Balanzat, J-M. Janot and S. Balme, Fast and reversible
functionalization of a single nanopore based on layer-by-layer polyelectrolyte self-assembly for tuning the current
rectification and designing sensors. RSC Adv, 2016, 6, 32228. IF 3.84
3. V. Thangaraj, M. Lepoitevin, M. Smietana, E. Balanzat, M. Bechelany, J-M. Janot, J-
J. Vasseur, S. Subramanian, S. Balme, Detection of short ssDNA and dsDNA by current-voltage measurements
using conical nanopores coated with Al2O3 by atomic layer deposition. Microchimica Acta, 2016, 183, 1011. IF
3.741
4. M. Lepoitevin, M. Bechelany, J-M. Janot, S. Balme, Nanopore functionalization for biological channel
mimicking. ScienceJet, 2015, 4, 188
5. M. Lepoitevin, P. E. Coulon, M. Bechelany, J. Cambedouzou, J-M. Janot, S. Balme, Influence of nanopore
surface charge and magnesium ion on polyadenosine translocation. Nanotechnology, 2015, 26, 144001. IF
3.672
6. M. Lepoitevin, G. Nguyen, M. Bechelany, E. Balanzat, J-M. Janot, S. Balme, Combining a sensor and pH-
gated Nanopore based on an Avidin-biotin system. ChemComm, 2015, 51, 5994. IF 6.718
7. M. Lepoitevin, M. Lemouel, M. Bechelany, J-M. Janot and S. Balme, Gold nanoparticles for the bare-eye
based and spectrophotometric detection of proteins, polynucleotides and DNA. Microchimica Acta, 2015, 182,
1223. IF 3.719
8. M. Lepoitevin, M. Jaber, R. Guegan, J. M. Janot, P. Dejardin, F. Henn and S. Balme, BSA and lysozyme
adsorption on homoionic montmorillonite: Influence of the interlayer cation. Applied Clay Science, 2014, 95,
396. IF 2.703
9. A. Abou Chaaya, M. Le Poitevin, S. Cabello-Aguilar, S. Balme, M. Bechelany, S. Kraszewski, F. Picaud, J.
Cambedouzou, E. Balanzat, J. M. Janot, T. Thami, P. Miele and P. Dejardin, Enhanced Ionic Transport
Mechanism by Gramicidin A Confined Inside Nanopores Tuned by Atomic Layer Deposition. Journal of Physical
Chemistry C, 2013. 117, 15306. IF 4.835
10. S. Balme, F. Picaud, S. Kraszewski, P. Dejardin, J. M. Janot, M. Lepoitevin, J. Capomanes, C. Ramseyer
and F. Henn, Controlling potassium selectivity and proton blocking in a hybrid biological/solid-state polymer
nanoporous membrane. Nanoscale, 2013, 5, 3961. IF 6.739
11. S. Balme, R. Guegan, J. M. Janot, M. Jaber, M. Lepoitevin, P. Dejardin, X. Bourrat and M. Motelica-Heino,
Structure, orientation and stability of lysozyme confined in layered materials. Soft Matter, 2013, 9, 3188. IF
4.151.

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Proceedings
1. M. Lepoitevin, M. Bechelany, , E. Balanzat, J-M. Janot S. Balme, Nanopore as a sensor based on avidin-
biotin system. Biophysical Journal, 2016, 110: p337a. doi: 10.1016/j.bpj.2014.11.2643
2. M. Lepoitevin, M. Bechelany, J. M. Janot, S. Balme, And P.E. Coulon, Influence Of Nanopore Surface
Charge On Polycytosine Translocation. Physics, Chemistry and Applications of Nanostructures, 2015,
pp. 457. doi: 10.1142/9789814696524_0113
3. S. Balme, M. Lepoitevin, M. Bechelany, And J. M. Janot, Hybrid Biological/Artificial Nanopore. Physics,
Chemistry and Applications of Nanostructures, 2015, pp. 454. doi:10.1142/9789814696524_0112
4. S. Balme, M. Lepoitevin, A. Abou-Chayaa, M. Bechelany, J-M. Janot, E. Balanzat, Biological Channel
Confinement in Nanostructured Nanopore. Biophysical Journal, 2015, 108: p484a. doi:
10.1016/j.bpj.2014.11.2643
Oral communications (speaker underlined)
1. M. Lepoitevin, M. Bechelany, E. Balanzat, J-M. Janot, S. Balme, Design of Biomimetic "Smart"
Nanopore: example of multi-responsive single nanopore (pH-gate and sensing. IP2 winter meeting, 11
February 2016, Montpellier, France.
2. M. Lepoitevin, P. E. Coulon, M. Bechelany, J. Cambedouzou, J-M. Janot, S. Balme, Influence of
nanopore surface charge on polycytosine translocation. Nanomeeting, 26-29 May 2015, Minsk, Belarus.
3. M. Lepoitevin, G. Nguyen, M. Bechelany, E. Balanzat, J-M. Janot, S. Balme, Combining a sensor and
pH-gated Nanopore based on an Avidin-biotin system. Seminar, Vilnius University, 21 May, Vilnius,
Lithuania.
4. M. Lepoitevin, M. Bechelany, J. M. Janot, S. Balme, Influence of Nanopore surface charge on
polyadenosine translocation. Journées Scientifiques de l’école doctorale Sciences Chimiques Balard,
19-20 November 2014, Montpellier, France.
5. S. Balme, S. Cabello-Aguillar, M. Lepoitevin, A. Abou-Chaaya, M. Bechelany, JM. Janot, E. Balanzat,
Potentiality of hybrid biological-artificial nanopore. Nature Inspired Chemistry Engineers, 15-17 October
2014, Nice, France.
6. S. Balme, S. Cabello-Aguillar, M. Lepoitevin, A. Abou-Chaaya, M. Bechelany, JM. Janot, P. Dejardin,
E. Balanzat, Potentiality of hybrid biological-artificial nanopore : for ionic separation and DNA sequencing
applications. Material Sciences and Engineering, 23-25 Septembre 2014, Darmstadt, Germany.
7. S. Balme, S. Cabello-Aguillar, M. Lepoitevin, A. Abou-Chaaya, M. Bechelany, JM. Janot, E. Balanzat,
Potentiality of Hybrid biological-artificial nanopore based on biological channel confinement. SICASE: (Seoul
International Conference on Applied Science and Engineering), 29-31 August 2014, Seoul, South
Corea.
8. M. Lepoitevin, M. Bechelany, J. M. Janot, F. Picaud, S. Balme Controlling potassium selectivity and
proton blocking in a hybrid biological/solid-state polymer nanoporous membrane. SICASE: (Seoul

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International Conference on Applied Science and Engineering), 29-31 August 2014, Seoul, South
Korea.
9. M. Lepoitevin, M. Bechelany, J. M. Janot, S. Balme Translocations of polynucleotides through a sub-5nm
SiN single pore and influence of Mg2+. Journée Interface Physicochimie, Polymères, 9 July 2014,
Montpellier, France.
10. S. Cabello-Aguillar, M. Lepoitevin, M. Bechelany, C. Pochat-Bohatier, JM. Janot, S. Balme, Technologie
Nanopore pour des applications diagnostics. Journée interne du pole Balard “Matériaux pour la Santé”,
2014, Montpellier, France.
11. M. Lepoitevin, S. Balme, F. Henn, Protein adsorption on homoionic alkali and alkali-earth montmorillonite:
influence of the extraframework cation. European Clay Conference – EUROCLAY, 26 Juin- 01 Juillet 2011,
Antalya, Turkey.
Posters (speaker underlined)
1. M. Lepoitevin, M.Bechelany, E. Balanzat, J-M. Janot, and S. Balme, Nanopore as a sensor based on
avidin-biotin system. 60th Biophysical Society annual meeting, 27 February- 2 March 2016, Los Angeles,
California.
2. M. Lepoitevin, M.Bechelany, E. Balanzat, J-M. Janot, and S. Balme, Mimicking pH and ligand gate with
a single channel using biotin-avidin system. Biophysics across scales: from single molecules to
organisms, 1-3 June 2015, Montpellier, France.
3. M. Lepoitevin, G. Nguyen, M.Bechelany, E. Balanzat, J-M. Janot, and S. Balme, Combining a sensor and
a pH-gated nanopore based on an avidin–biotin system. SwissNanopore: Selective transport through
nanopores: physics meets biology , 22-27 March 2015, Lenzerheide, Switzerland.
4. S. Balme, M. Lepoitevin, A. Abou-Chayaa, M. Bechelany, J-M. Janot, E. Balanzat, Biological Channel
Confinement in Nanostructured Nanopore. Biophysical Society 59th annual meeting, 7-11 February 2015,
Baltimore, Maryland, Etats-Unis.
5. M. Lepoitevin, M. Bechelany, J. M. Janot, F. Picaud, S. Balme, Controlling Potassium Selectivity and
Proton Blocking by Gramicidin a Confined Inside Track-Etched Membrane. Material Sciences and
Engineering, 23-25 September 2014, Darmstadt, Allemagne.
6. M. Lepoitevin, M. Bechelany, J. M. Janot, F. Picaud, S. Balme, Ionic transport properties of gramicidin A
confined inside nanopore. 1ères Journées Méditerranéennes des Jeunes Chercheurs, 17-18 October
2013, Montpellier, France.
7. D. Saurel, M. Lepoitevin, M. Casas Cabanas, M. Galceran Mestres, B. Acebedo, T. Rojo, New insights
into the kinetics of Na insertion and extraction into the FePO4/NaFePO4 system. 224th ECS Meeting, 27
October - 1 November 2013, San Francisco.