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case presentation :
mucus extravasation cyst
By: Dr Ahmed Adel
Under supervision :
Dr Heba farag
Dr rehab fawzy
 Patient name : Hassan Abosalem
 Age : 52
 Sex : Male
 Occupation : Taxi Driver
 No of specimens : 1
 Medical history : free
 Intrabony or extrabony : extrabony
 Colour :bluish red
 Size : 7ml x 7ml
 Soft or hard : soft
 Site : upper lip
 relation to teeth : upper canine
 Condition of corrosponding related teeth : vital
 X-ray : -ve
Clinical picture :
After surgery removal :
Tissue processing :
 1-Fixation :
 Lesion kept in 10% formalin for 24 h to maintain morphological shape
Of the cell and stop autolysis process and kill microbes and bacteria
Dehydration
 Dehydration of the lesion by different concentration of ethyl alcohol
50% » 70% »90% for 1h
to speed process left in oven 30 min (cant be used in bone )
Clearing
 Remove fats and lipid by xylene 30 min
Infiltration
 By remove xylene and enter paraffin to compensate shrinkage due to loss
of fats and liquid at oven temperature 60 for 2h
Blocking
 Put specimen into block at paraffin (preparing block )
Cutting
 Cutting by microtone 10 – 4 micron
Clearance
 Remove paraffin in oven before staining
Staining
 Staining by hematoxylin eosin
Examination under M.S
Cavity filled
with mucin
pool
40x
Sebaceous
gland
40x
Hair follicle
40x
Surrounded by
compressed
fibrous &
granulation
tissue
Muscle
fiber
100x
Final result
 Microscopic examination of H&E paraffin section reveals cavity containing
mucin pool surrounded by compressed fibrous & granulation tissue
infiltrated by few number of chronic inflammatory cell
 Part of C.T showing some sebaceous gland and hair follicle and few muscle
fiber
Diagnosis
Mucous extravasation cyst
Cyst characteristic
 Mucoceles and ranula are retention or extravasation cyst occurring due to
trauma or blockage to the duct of sublingual or minor salivary gland
 Mucocele occur anywhere of the oral cavity except the floor of the mouth
but ranula occur in the floor of the mouth
Mucous extravasation cyst
 Arising from severance of salivary duct due to trauma such as that
produced by biting the lips or cheek so that a continuous pooling of
mucous occurs in the tissue
 It is considered a pseudo cyst due to :
1- its wall is made up of compressed fibrous connective tissue
2-the lumen is filled with an eosinophilic coagulum and mucous
Thank you

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pathology 2.pptx