Marina De Luca is a biotechnologist living in Germany with expertise in proteomics. She has a Master's degree in Agro-Industrial Biotechnology from the University of Verona, where she conducted her thesis on differential proteomic analysis of a major depression model in rat brain. Her work experience includes an internship at GlaxoSmithKline analyzing a depression model using proteomic and statistical analysis techniques. She has published papers on proteomic changes in rat brain tissue after antidepressant treatment.

1. MARINA DE
LUCA
BIOTECHNOLOGIST
marina.biotech@gmail.c
om
+49 152 16091201
Name and surname: Marina De Luca
Location: 73257 Köngen, Baden-Württemberg, Germany
Phone number: +49 152 16091201
Email address: marina.biotech@gmail.com
Date of birth: Jun 23, 1981
Citisenship: Italian National
Place of birth: Verona, Italy
Status: Married
Work Experience
06.2006 – 07.2007 Internship at GlaxoSmithKline (Thesis of university
degree)
Psychiatry CEDD, Biology Department | Verona, Italia
Analysis of a major depression model as part of project “Gendep”. The aim
of the project is a better functional characterization of the molecular
mechanisms of the depression therapy through the integration of scientific
results obtained from clinic and pre-clinic research area. Analysis conducted
using differential proteomic approach based on bi-dimensional
electrophoresis with mass spectrometry and analyzing results using PD-
Quest software, t-Student and Partial Least Square (PLS) statistical tests.
Using mass spectrometry, the modulated proteins were identified using
peptide-mass fingerprinting.
Technical acquired skills:
• Proteomics (2D - Electrophoresis and image analysis)
• Biochemistry (Western blotting)
Publications:
• Carboni L., Piubelli C., De Luca M., Gruber S., Andersson W., El Khoury,
A. Mathé A.A., Domenici E. Proteome changes in rat hippocampus and
pre-frontal/frontal cortex in Flinders rats after Nortriptyline treatment. Eur.
Neuropsychopharmacol. 18(4):S355-S356, 2008.
• Gasperini L, Becchi S, Piubelli C, De Luca M. Gruber S, Andersson W, El
Khoury A, Mathé AA, Domenici E, Carboni L. Proteomic analysis of
hippocampus and frontal/pre-frontal cortex in a major depression model,
the Flinders rat, after nortriptilin administration. XVI
Neuropsycopharmacological Society Meeting, 2008, Milan, Italy.
Curriculum Vitae Marina De Luca Last update: October 23, 2015 Page 1 of 2

2. Education
09.2000 – 07.2009 Master of Science in Agro-Industrial Biotechnology
University of Verona | Verona, Italy
Thesis: Differential proteomic analysis of a major depression model
based on gene-environment interaction with antidepressant treatment on rat
brain.
Final mark: 100/110
Supervisor: Dr. Daniela Cecconi
Co-examiner: Lucia Carboni, PhD (GlaxoSmithKline)
09.1995 – 07.2000 Technical diploma of Chemical-Biological laboratory (High
School)
IPSIA ”Enrico Fermi“ | Verona, Italy
Final mark: 82/100
Technical skills
PROTEOMICS
• Protein extraction, dialysis and determination of protein concentration.
• SDS-PAGE.
• 2D electrophoresis and image analysis, Western blot analysis.
GENOMICS
• Plasmid DNA preparation, genomic DNA isolation from vegetal tissues, DNA purification
from gel and from solution, RNA extraction from vegetal tissues.
• Cloning techniques, PCR, RT-PCR, molecular hybridization techniques (Southern Blot,
Northern Blot).
• Hybridization with Church radioactive probe, OGM analysis (inverted CTAB method,
WIZARD, and PCR), competent cellular preparation with CaCl2, electroporation and
transformation.
COMPUTER SKILLS
• Operating Systems: Microsoft Windows 7, Vista, XP, Linux Ubuntu.
• Office software: Microsoft Word, Excel, Power Point;
• Bioinformatics tools: Swiss-Prot, Prosite, Pfam, NCBI Entrez, ExPASy, Clustalw, PSI-Blast,
Phylip, ProtDist, Blast, Fasta.
• Bibliographic research.
Personal Skills
Italian Mother tongue
English Medium
(Marina De Luca)
Curriculum Vitae Marina De Luca Last update: October 23, 2015 Page 2 of 2