Dendritic cells are a type of white blood cell that are part of the innate immune system. They are named for their long membrane extensions resembling dendrites. Their main function is to process antigens and present them on their surface to T-cells, acting as antigen presenting cells. Dendritic cells can be found in the skin, inner linings of the nose, lungs, stomach and intestines, and in an immature state in the blood. They activate T-cells, induce immune tolerance, and help maintain immune memory with B-cells.

1. DENDRITIC
CELLS

2. DENDRITIC CELLS (DCs) : Dendritic cells are
a type of white blood cells and components of innate
immune system.
• It acquired its name because it is covered with long
membrane extensions that resemble the dendrites of
nerve cells.
• Their main function is to process antigen material and
present it on the surface to T-cells, thus functioning as
antigen presenting cells.
Innate immunity : The innate immune system is the
earliest line of defense against microbes and includes
cellular and chemical barriers including skin, mucosal
epithelia, dendritic cells, cytokines, macrophages, NK
cells and antimicrobial peptides

3. LOCATION OF DCs
• Skin (Langerhans cells, dermal
dendritic cells).
• Inner lining of nose, lungs, stomach
and intestines.
• They can also be found in an
immature state in the blood.

4. IMMATURE DCs MATURE DCs

5. TYPES OF DENDRITIC
CELLS
 LANGERHANS CELLS
 DERMAL DENDRITIC CELLS
 MELANOCYTES
 MERKEL CELLS

6. FUNCTIONS OF DCs
• Antigen presentation and activation of T-
cells.
• Inducing and maintaining immune
tolerance.
• Maintain immune memory in tandem with
B-cells.
Dendritc
cellT-Cell

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