The document discusses the emergence and challenge of methicillin-resistant Staphylococcus aureus (MRSA) in healthcare settings, focusing on strategies for prevention and control. It emphasizes the importance of effective measures such as early detection, antibiotic therapy, isolation precautions, and handwashing to reduce mortality, morbidity, and the burden of MRSA. The paper aims to provide evidence-based practices for managing and preventing MRSA transmission, particularly among high-risk patients.

1. PreventionofMRSAintheHealthcareSetting
Evidence-BasedPracticePaperSample
Abstract
TheTheemergenceofanantibiotic-resistantbacteriaintroducesachallengingand
new issuesinthefieldofhealthcare.Ananalysisinvolvingmultipleresearch
articleswasconductedinordertolookforthebestpracticeforboththeprevention
andthespreadoftheMethicillin-ResistantStaphyloccocusAureus(MRSA)inthe
healthcaresetting.Itsimportanceinthehealthcaresettingincludesdecreasing
mortalityandmorbidity,providingprotectiontothecriticalmedicalresources,
whilereducingitsoverallburdenonhealth.Somepatientsareatarelativelyhigher
risriskforcontractingMRSA.Assuch,differentavenuesneedtobefurtherexploredso
astopreventfastertransmission.Thesealsoincludesearlydetection,antibiotic
therapy,isolationprecautions,aswellashandwashing.Thispaperwillofferthe
bestevidenceforpreventingthespreadofthispossiblyfatalbacterium.
AimofthePaper
Whatdoliteraturesshowasthebestwayincontrollingthepossiblespreadof
MRSAwithinthehealthcaresetup?Theprimaryaimofthispaperistolookclosely
intothebestevidencesinvolvedincontrollingthepotentialspreadofthis
antibiotic-resistantbacteria.Itisveryimportanttoimplementeffectivestrategies
inpreventingwithinthehospitalsetting.Thiswillhelpprotectthecriticalmedical
resources,decreasemortalityandmorbidity,protectthepatientsandthefacility
workers,whiledecreasingtheoverallburdenbroughtbytheMRSAinthehealth
caresettingcaresetting.

2. PreventionofMRSAintheHealthcareSetting
SupportforRelevance
TheoccurrenceoftheMRSAwasreportedinitiallyin1961,inUnitedKingdom.It
wasdiscoveredthatStaphyloccocusAureusinfectionswerehighlybecoming
resistanttomethicillin,asabeta-lactuminhibitor(Romain,Tester&O’Neill,2008).
MRSAalsoranksasamongtheprevalentpathogensamonghospitalsworldwide
(Diethelm&Clima,2010).Infectionsthatarecausedbyamulti-drugresistantand
gram-positivebacteriafurtherrepresentsaprimarypublichealthburdenwhenit
comestomortalityandmorbidity,increasedexpensesinthefieldofpatient
managemenmanagement,aswellastheimplementationofmeasurestocontrolinfection.
(William&Langley,2011).StaphyloccocusAureusisarecognizedpathogeninthe
hospitalsetting.Whentalkingaboutmulti-drugresistance,ithasthetendencyto
complicatetherapy.Ithasalsobeenreferredtoasa“superbug”,regularlyattracting
interestfrom themedia.ThereisalsoapoliticalpressurethatreducesMRSA
infectionrates.
Somepatientsareusuallyatahigherriskofcontractingthisbacteria.This
includespatientswhohadpreviousMRSAinfection.Thesearepatientswhohave
previouslybeenhospitalized,atleastthriceormoretimesinasingleyear,those
whohavebeenlong-termresidentsoflong-termcarefacilities,aswellaspatients
whoaredealingwithchronicwounds.Throughscreeningofthesehigh-risk
patients,accurateisolationmeasurescanbeappliedrightintoplacesothatthe
transmissiontowardsotherpatients,aswellastotheircaregiversmayalsobe
prprevented.
Evidence-BasedPracticePaperSample

3. Antibiotictherapyandisolationalonearenotenoughtostoptransmissionof
StaphyloccocusAureusfromapersontoanother,whetheritwithinpatients,orto
thecaregivers.Theprimarymodeoftransmissionisthroughthehands,particularly
throughthehandsofthehealthcareworkers.Aspresentedbyvarioushand
washingstudies,theactofhandwashinghasbeenshowntobeaveryimportant
factorwhenitcomestoreducingthepotentialspreadofmicroorganisms.However,
allofthesestudiesshowthatalotofhealthcareworkersdonotpracticetheright
wawayofperforminghandhygienewhenitcomestotakingcareofvariouspatients.
SummaryoftheEvidence
AccordingtoRomainetal.(2008),about30%ofthepopulationofhealthypeople
carriestheStaphyloccocusAureuswithintheiranteriornares(p.42).Thisisoften
associatedwiththeincreaseinriskofinfectionsaftersurgery.Atthesametime,
about80%ofinfectionsthatarecategorizedasinvasivenosocomialcomesfrom
endogenousoriginamongnasalcarriers(Romain,etal.,2008).
Earlydetectionofthesecarriersisveryimportantwhenitcomestotheprevention
ofStaphyloccocusAureusinfection.Forstaffandhealthcareworkers,proper
protectiveattireshouldbechanged,whileappropriatehandhygieneshouldbe
observedinbetweenpatientcontacts.
References
Diethelm,H.&Clima,C(2010).StaphyloccocusAureusanditspoweronthehumanbody.PathologicalDisorder
Journal,23(2),134-144.
RRomain,H.D.,Tester,H.&O’Neill,A.(2008).StatisticsonMRSA–Updated.PathologicalDisorderJournal,12(2),
42-44.
William,H.&Langley,T.(2011).TransmissionofMRSAinthehealthcaresetting.HealthcareSociety,45(4),12-15.
PreventionofMRSAintheHealthcareSetting
Evidence-BasedPracticePaperSample