2. Causes
• First reported 1982 - Forssmanet et al
• Secondary to
1. Dilatation and curettage
2. Caesarean section
3. Gestational trophoblastic disease
4. Uterine malignancies
3. • Trauma to endothelium during curettage
• Increased myometrial VEGF angiogenesis and
revascularisation have been noted after hysteroscopy for
Asherman`s.
• Biological aberration of the placental bed during
deplacentation
• Venous sinuses become incorporated within the
myometrium after necrosis of chorionic villi
4. CASE REPORT
• P1A2 with previous LSCS 6 years ago
• Previous history- medical abortion followed by D&C
• Present - failed medical abortion with retained pregnancy
• USG- 7 weeks IU pregnancy
• Severe chest infection
5. • Dilation , suction evacuation and curettage 15th march
• Preceded by Misoprost per vaginal and oxytocin in IV drip
• Under antibiotic cover
• Excess vascular arena observed
• Cavity felt empty
• Blood with ?conception product obtained and sent for
HPE
6. • HPE-
• Blood clots and fibrin
• Few chorionic villi
• partly degenerated
• Occasional decidua and neutrophilic infiltrates
9. • Beta HCG on 1month follow up
• Shows declining trend from 81.3 to 5.77
• PSTT has to be ruled out.
• Advised UA embolisation in view of extensive
malformation
• Delayed
• Massive bleed after a few days
22. Conclusion
1. AVM can lead to massive HMB
2. More number of cases need to be studied
3. Treatment modalities are
A. spontaneous resolution
B.Medical- GnRH, OCP , Methyl ergometrine
C.UAE
D.Hysterectomy in some cases