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Uterine arteriovenous
malformation
(Acquired)
Dr Mamta Lekhi
Sr Consultant Obstetrician and Gynaecologist
MAMTA MEDICARE CENTRE
East Delhi
Causes
• First reported 1982 - Forssmanet et al
• Secondary to
1. Dilatation and curettage
2. Caesarean section
3. Gestational trophoblastic disease
4. Uterine malignancies
• Trauma to endothelium during curettage
• Increased myometrial VEGF angiogenesis and
revascularisation have been noted after hysteroscopy for
Asherman`s.
• Biological aberration of the placental bed during
deplacentation
• Venous sinuses become incorporated within the
myometrium after necrosis of chorionic villi
CASE REPORT
• P1A2 with previous LSCS 6 years ago
• Previous history- medical abortion followed by D&C
• Present - failed medical abortion with retained pregnancy
• USG- 7 weeks IU pregnancy
• Severe chest infection
• Dilation , suction evacuation and curettage 15th march
• Preceded by Misoprost per vaginal and oxytocin in IV drip
• Under antibiotic cover
• Excess vascular arena observed
• Cavity felt empty
• Blood with ?conception product obtained and sent for
HPE
• HPE-
• Blood clots and fibrin
• Few chorionic villi
• partly degenerated
• Occasional decidua and neutrophilic infiltrates
USG
• Intensely vascular AV malformation with no
trophoblastic signals
Type to enter a caption.
• Beta HCG on 1month follow up
• Shows declining trend from 81.3 to 5.77
• PSTT has to be ruled out.
• Advised UA embolisation in view of extensive
malformation
• Delayed
• Massive bleed after a few days
MR imaging after bleeding
controlled
Increased T2 signal
Managed by UAE
• Under fluoroscopic guidance
• Right femoral artery access
• Bilateral uterine arteries selectively catheterised
• Contrast showed dilated and tortuous uterine arteries
suggestive of AVM
• 4ml 30% glue and 1.3ml 40 % glue
• Post UAE check ultrasound
• Echogenic focus seen in uterus- glue cast
• No residual nidus seen
• Lesion shown on colour doppler
Conclusion
1. AVM can lead to massive HMB
2. More number of cases need to be studied
3. Treatment modalities are
A. spontaneous resolution
B.Medical- GnRH, OCP , Methyl ergometrine
C.UAE
D.Hysterectomy in some cases
Thank you

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Uterine arteriovenous malformation Acquired Dr Mamta Lekhi

  • 1. Uterine arteriovenous malformation (Acquired) Dr Mamta Lekhi Sr Consultant Obstetrician and Gynaecologist MAMTA MEDICARE CENTRE East Delhi
  • 2. Causes • First reported 1982 - Forssmanet et al • Secondary to 1. Dilatation and curettage 2. Caesarean section 3. Gestational trophoblastic disease 4. Uterine malignancies
  • 3. • Trauma to endothelium during curettage • Increased myometrial VEGF angiogenesis and revascularisation have been noted after hysteroscopy for Asherman`s. • Biological aberration of the placental bed during deplacentation • Venous sinuses become incorporated within the myometrium after necrosis of chorionic villi
  • 4. CASE REPORT • P1A2 with previous LSCS 6 years ago • Previous history- medical abortion followed by D&C • Present - failed medical abortion with retained pregnancy • USG- 7 weeks IU pregnancy • Severe chest infection
  • 5. • Dilation , suction evacuation and curettage 15th march • Preceded by Misoprost per vaginal and oxytocin in IV drip • Under antibiotic cover • Excess vascular arena observed • Cavity felt empty • Blood with ?conception product obtained and sent for HPE
  • 6. • HPE- • Blood clots and fibrin • Few chorionic villi • partly degenerated • Occasional decidua and neutrophilic infiltrates
  • 7. USG • Intensely vascular AV malformation with no trophoblastic signals Type to enter a caption.
  • 8.
  • 9. • Beta HCG on 1month follow up • Shows declining trend from 81.3 to 5.77 • PSTT has to be ruled out. • Advised UA embolisation in view of extensive malformation • Delayed • Massive bleed after a few days
  • 10. MR imaging after bleeding controlled Increased T2 signal
  • 11. Managed by UAE • Under fluoroscopic guidance • Right femoral artery access • Bilateral uterine arteries selectively catheterised • Contrast showed dilated and tortuous uterine arteries suggestive of AVM • 4ml 30% glue and 1.3ml 40 % glue
  • 12. • Post UAE check ultrasound • Echogenic focus seen in uterus- glue cast • No residual nidus seen
  • 13.
  • 14. • Lesion shown on colour doppler
  • 15.
  • 16.
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  • 21.
  • 22. Conclusion 1. AVM can lead to massive HMB 2. More number of cases need to be studied 3. Treatment modalities are A. spontaneous resolution B.Medical- GnRH, OCP , Methyl ergometrine C.UAE D.Hysterectomy in some cases