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NON-VENEREAL
TREPONEMATOSIS
18.3.19
Dr. Jerriton Brewin,
1St Year PG, DVL, SVMC
YAWS
CAUSE
T. Pallidum pertenue
EPIDEMIOLOGY
• Rural area
• Tropical belt
• High humidity
• Poor hygiene
• Early childhood
• M > F
TRANSMISSION
• Skin-to-skin
• Flies (Hippelates pallipes)
INCUBATION
3 – 6 weeks
PINTA
CAUSE
T. Pallidum carateum
EPIDEMIOLOGY
• Rural area
• Central and South America
• Poor hygiene
• Crowded area
• Half patients < 15 years
• M = F
TRANSMISSION
• Skin-to-skin
• Insects
INCUBATION
1 – 8 weeks
 Most benign
 Has only skin involvement
ENDEMIC SYPHILIS (BEJEL)
CAUSE
T. Pallidum endemicum
EPIDEMIOLOGY
• Nomads in the Arab Peninsula
• Dry and arid climates
• Poor hygiene
• Overcrowding
• Children < 15 years (80%)
TRANSMISSION
• Skin-to-skin/mucus membrane
• Shared food
• Fomites
INCUBATION
2 – 4 weeks
 C/F resemble venereal syphilis
 Has predominant mucosal involvement
DIAGNOSIS
• High endemicity – clinical diagnosis
• Eosinophilia (Pinta)
• Darkfield microscopy of serous exudate
• Serology (Treponemal & Non-treponemal)
• Skin biopsy (treponema identification with silver
stain & immunofluorescence)
WHO mass treatment eradication campaigns = 7- to 10-day
course of oral penicillin, at a dose of 50 mg/kg per day in four
divided doses up to 1,200 mg daily.
REFERENCES
• VK Sharma, STIs.
• Bhushan Kumar, STIs.
• Fitzpatrick’s Dermatology
• Rook’s Textbook of Dermatology

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Non Venereal Treponematosis

Editor's Notes

  1. West and Central Africa, South America
  2. West and Central Africa, South America
  3. Decapitated yaws – mother yaw is absent and directly goes to secondary stage, seen in 10%
  4. West and Central Africa, South America
  5. West and Central Africa, South America
  6. West and Central Africa, South America